Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Robert Wiesheu"'
Autor:
Sandeep Dhayade, Matthias Pietzke, Robert Wiesheu, Jacqueline Tait-Mulder, Dimitris Athineos, David Sumpton, Seth Coffelt, Karen Blyth, Alexei Vazquez
Publikováno v:
Nutrients, Vol 12, Iss 8, p 2181 (2020)
Current nutritional recommendations are focused on energy, fat, carbohydrate, protein and vitamins. Less attention has been paid to the nutritional demand of one-carbon units for nucleotide and methionine synthesis. Here, we investigated the impact o
Externí odkaz:
https://doaj.org/article/a633024cab7a40c69edb44820ab47d1d
Autor:
Daniel J. Murphy, Jennifer P. Morton, Owen J. Sansom, Seth B. Coffelt, Leo M. Carlin, Andrew V. Biankin, William Clark, Colin Nixon, Katarina Gyuraszova, Saadia A. Karim, Curtis Rink, Sarah Neidler, Robin Shaw, Rosanna Upstill-Goddard, Björn Kruspig, Sarah Laing, Ann Hedley, Declan Whyte, Robert Wiesheu, Ximena Raffo-Iraolagoitia, Tiziana Monteverde, Nathiya Muthalagu
Spreadsheet of genes co-regulated by MYC & Miz1 in KMC PDAC cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::85445eb0df2a3b684d67a96845226776
https://doi.org/10.1158/2159-8290.22535632.v1
https://doi.org/10.1158/2159-8290.22535632.v1
Autor:
Daniel J. Murphy, Jennifer P. Morton, Owen J. Sansom, Seth B. Coffelt, Leo M. Carlin, Andrew V. Biankin, William Clark, Colin Nixon, Katarina Gyuraszova, Saadia A. Karim, Curtis Rink, Sarah Neidler, Robin Shaw, Rosanna Upstill-Goddard, Björn Kruspig, Sarah Laing, Ann Hedley, Declan Whyte, Robert Wiesheu, Ximena Raffo-Iraolagoitia, Tiziana Monteverde, Nathiya Muthalagu
MYC is implicated in the development and progression of pancreatic cancer, yet the precise level of MYC deregulation required to contribute to tumor development has been difficult to define. We used modestly elevated expression of human MYC, driven f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0cd13536b16418ef57a51deb42fe2576
https://doi.org/10.1158/2159-8290.c.6547897.v1
https://doi.org/10.1158/2159-8290.c.6547897.v1
Autor:
Daniel J. Murphy, Jennifer P. Morton, Owen J. Sansom, Seth B. Coffelt, Leo M. Carlin, Andrew V. Biankin, William Clark, Colin Nixon, Katarina Gyuraszova, Saadia A. Karim, Curtis Rink, Sarah Neidler, Robin Shaw, Rosanna Upstill-Goddard, Björn Kruspig, Sarah Laing, Ann Hedley, Declan Whyte, Robert Wiesheu, Ximena Raffo-Iraolagoitia, Tiziana Monteverde, Nathiya Muthalagu
6 supplementary Figures with legends under each; 3 Supplementary Tables; Supplementary Methods and References
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::040c578ef9926147b6216f683a201ac6
https://doi.org/10.1158/2159-8290.22535635.v1
https://doi.org/10.1158/2159-8290.22535635.v1
Autor:
Toshiyasu Suzuki, Anna Kilbey, Rachel A. Ridgway, Hannah Hayman, Ryan Bryne, Nuria Casa Rodríguez, Anastasia Georgakopoulou, Lei Chen, Michael Verzi, David Gay, Ester G. Vázquez, Hayley L. Belnoue-Davis, Kathryn Gilroy, Anne Helene Køstner, Christian Kersten, Chanitra Thuwajit, Ditte Andersen, Robert Wiesheu, Anett Jandke, Natalie Roberts, Karen Blyth, Antonia Roseweir, Simon J. Leedham, Philip D. Dunne, Joanne Edwards, Adrian Hayday, Owen J. Sansom, Seth B. Coffelt
WNT/β-catenin signaling endows cancer cells with proliferative capacity and immune-evasive functions that impair anti-cancer immunosurveillance by conventional, cytoxtoic T cells. However, the impact of dysregulated WNT signalling on unconventional,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dda07a1fd5bdde7fa6e738a8786d603a
https://doi.org/10.1101/2022.06.10.495115
https://doi.org/10.1101/2022.06.10.495115
Autor:
Sophie Curio, Sarah C Edwards, Toshiyasu Suzuki, Jenny McGovern, Chiara Triulzi, Nagisa Yoshida, Gustav Jonsson, Teresa Glauner, Damiano Rami, Robert Wiesheu, Anna Kilbey, Rachel Violet Purcell, Seth B Coffelt, Nadia Guerra
Publikováno v:
Discovery immunology. 1(1)
γδT cells are unconventional T cells particularly abundant in mucosal tissues that play an important role in tissue surveillance, homeostasis, and cancer. γδT cells recognize stressed cells or cancer cells through the NKG2D receptor to kill these
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bffc51f4c494889fc2741c81fcbf242c
https://pubmed.ncbi.nlm.nih.gov/36277678
https://pubmed.ncbi.nlm.nih.gov/36277678
Autor:
Glauner T, Crispin J. Miller, Kristina Kirschner, Robert Wiesheu, Robin M. Shaw, Ann Hedley, Sarah C. Edwards, Nizar N. Batada, Anna Kilbey, Seth B. Coffelt, Katerina Boufea, Kevin G. Blyth, Hoevenaar Whm
IL-17A-producing γδ T cells within the lung consist of both Vγ6+tissue-resident cells and Vγ4+circulating cells that play important roles in homeostasis, inflammation, infection, tumor progression and metastasis. How these γδ T cell subsets are
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cd600705e571a8aad7bc4e88faf79af2
https://doi.org/10.1101/2021.07.04.451035
https://doi.org/10.1101/2021.07.04.451035
Autor:
Sarah C. Edwards, Ann Hedley, Wilma H.M. Hoevenaar, Robert Wiesheu, Teresa Glauner, Anna Kilbey, Robin Shaw, Katerina Boufea, Nizar Batada, Shinya Hatano, Yasunobu Yoshikai, Karen Blyth, Crispin Miller, Kristina Kirschner, Seth B. Coffelt
Publikováno v:
The Journal of experimental medicine. 220(2)
IL-17A–producing γδ T cells in mice consist primarily of Vγ6+ tissue-resident cells and Vγ4+ circulating cells. How these γδ T cell subsets are regulated during homeostasis and cancer remains poorly understood. Using single-cell RNA sequencin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f5331d7f2008a745797a43a4383c0cbc
https://pubmed.ncbi.nlm.nih.gov/36480166
https://pubmed.ncbi.nlm.nih.gov/36480166
Autor:
Seth B. Coffelt, Sarah-Jane Remak, Sarah C. Edwards, Kristina Kirschner, Anna Kilbey, Karen Blyth, Ann Hedley, Marie Tosolini, Crispin J. Miller, Jean-Jacques Fournié, Robert Wiesheu
In mice, IFNγ-producing γδ T cells that express the co-stimulatory molecule, CD27, play a critical role in host defence and anti-tumour immunity. However, their phenotypic diversity, composition in peripheral and secondary lymphoid organs, similar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d4cecc8bf0407ffc0d85a35820de8bd5
https://doi.org/10.1101/2020.09.08.287854
https://doi.org/10.1101/2020.09.08.287854
Autor:
Jacqueline Tait-Mulder, Seth B. Coffelt, Matthias Pietzke, Dimitris Athineos, Robert Wiesheu, Alexei Vazquez, Sandeep Dhayade, Karen Blyth, David Sumpton
Publikováno v:
Nutrients
Nutrients, Vol 12, Iss 2181, p 2181 (2020)
Volume 12
Issue 8
Nutrients, Vol 12, Iss 2181, p 2181 (2020)
Volume 12
Issue 8
Current nutritional recommendations are focused on energy, fat, carbohydrate, protein and vitamins. Less attention has been paid to the nutritional demand of one-carbon units for nucleotide and methionine synthesis. Here, we investigated the impact o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::355f269ac1cfbb756ab6520cbea7042f
https://eprints.gla.ac.uk/218979/1/218979.pdf
https://eprints.gla.ac.uk/218979/1/218979.pdf