Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Robert Wellings"'
Autor:
Mitch Dowsett, Lesley-Ann Martin, Irene Kuter, Jill Walker, Robert Wellings, Justin Lindemann, Alan Mackay, Roger A'hern, Qiong Gao, Elizabeth Anderson, Ricardo Ribas, Zara Ghazoui, Helen Anderson, Anita K. Dunbier, Neill Patani
PDF file - 556KB, Supplementary Figure 1a: Overview of pre-surgical studies: Fulvestrant (NEWEST), detailing study design (i) and samples (ii). S1b: Anastrozole (FAIMoS), detailing study design (i) and samples (ii). S1c: Summary of patient demographi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::111e13ef549e981ecf054f8f3de8a756
https://doi.org/10.1158/1078-0432.22451022
https://doi.org/10.1158/1078-0432.22451022
Autor:
Mitch Dowsett, Lesley-Ann Martin, Irene Kuter, Jill Walker, Robert Wellings, Justin Lindemann, Alan Mackay, Roger A'hern, Qiong Gao, Elizabeth Anderson, Ricardo Ribas, Zara Ghazoui, Helen Anderson, Anita K. Dunbier, Neill Patani
PDF file - 29KB
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::61de8e34e2e274518b28685f3f88fc68
https://doi.org/10.1158/1078-0432.22451025
https://doi.org/10.1158/1078-0432.22451025
Autor:
Mitch Dowsett, Lesley-Ann Martin, Irene Kuter, Jill Walker, Robert Wellings, Justin Lindemann, Alan Mackay, Roger A'hern, Qiong Gao, Elizabeth Anderson, Ricardo Ribas, Zara Ghazoui, Helen Anderson, Anita K. Dunbier, Neill Patani
PDF file - 33KB, Impact of fulvestrant and E-deprivation on selected index proliferation-associated or E-regulated genes.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d5c1ce69d785e1bd0d98d989ec96531
https://doi.org/10.1158/1078-0432.22451019
https://doi.org/10.1158/1078-0432.22451019
Autor:
Mitch Dowsett, Lesley-Ann Martin, Irene Kuter, Jill Walker, Robert Wellings, Justin Lindemann, Alan Mackay, Roger A'hern, Qiong Gao, Elizabeth Anderson, Ricardo Ribas, Zara Ghazoui, Helen Anderson, Anita K. Dunbier, Neill Patani
PDF file - 147KB, S7: Ingenuity based analysis of genes affected by E-deprivation: (a) In vitro and (b) FAIMoS (two weeks) detailing (i) canonical pathways (p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a8fd6597129e57d38a7284b6cdacb57
https://doi.org/10.1158/1078-0432.22451007
https://doi.org/10.1158/1078-0432.22451007
Autor:
Mitch Dowsett, Lesley-Ann Martin, Irene Kuter, Jill Walker, Robert Wellings, Justin Lindemann, Alan Mackay, Roger A'hern, Qiong Gao, Elizabeth Anderson, Ricardo Ribas, Zara Ghazoui, Helen Anderson, Anita K. Dunbier, Neill Patani
PDF file - 127KB, S9: Fold-changes and statistical significance of genes significantly and differentially affected by fulvestrant and E-deprivation in pre-surgical studies and in vitro models: (a) Up-regulated and (b) Down-regulated. Probes are annot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::292cdcf698e8543d18b01c4aa3c5cbd0
https://doi.org/10.1158/1078-0432.22451004.v1
https://doi.org/10.1158/1078-0432.22451004.v1
Autor:
Mitch Dowsett, Lesley-Ann Martin, Irene Kuter, Jill Walker, Robert Wellings, Justin Lindemann, Alan Mackay, Roger A'hern, Qiong Gao, Elizabeth Anderson, Ricardo Ribas, Zara Ghazoui, Helen Anderson, Anita K. Dunbier, Neill Patani
PDF file - 58KB, S11: Summary of Spearman correlations between up-regulated (n=13) and down-regulated (n=28) genes which were fulvestrant-related (n=41), AURKA and ESR1, in pre-treatment in samples from (a) NEWEST and (b) FAIMoS; S12: Summary of trea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6bf24d755240702e625cb973b5ae4004
https://doi.org/10.1158/1078-0432.22451013
https://doi.org/10.1158/1078-0432.22451013
Autor:
Mitch Dowsett, Lesley-Ann Martin, Irene Kuter, Jill Walker, Robert Wellings, Justin Lindemann, Alan Mackay, Roger A'hern, Qiong Gao, Elizabeth Anderson, Ricardo Ribas, Zara Ghazoui, Helen Anderson, Anita K. Dunbier, Neill Patani
XLSX file - 1531KB, Details of transcripts and Gene Ontology (GO) functional sets resulting from comparative analyses. Probes are annotated with gene symbols where available.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::845bf058b7743f4094431700ba451e17
https://doi.org/10.1158/1078-0432.22451016
https://doi.org/10.1158/1078-0432.22451016
Autor:
Mitch Dowsett, Lesley-Ann Martin, Irene Kuter, Jill Walker, Robert Wellings, Justin Lindemann, Alan Mackay, Roger A'hern, Qiong Gao, Elizabeth Anderson, Ricardo Ribas, Zara Ghazoui, Helen Anderson, Anita K. Dunbier, Neill Patani
PDF file - 134KB, S3: Top 30 genes significantly affected by E-deprivation: (a) In vitro and (b) FAIMoS (two weeks), (i) Up-regulated and (ii) Down-regulated. Probes are annotated with gene symbols where available; S4: Top 30 genes significantly affe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71da84f941795c2e5fbd069dcf8dd442
https://doi.org/10.1158/1078-0432.22451010.v1
https://doi.org/10.1158/1078-0432.22451010.v1
Autor:
Mitch Dowsett, Lesley-Ann Martin, Irene Kuter, Jill Walker, Robert Wellings, Justin Lindemann, Alan Mackay, Roger A'hern, Qiong Gao, Elizabeth Anderson, Ricardo Ribas, Zara Ghazoui, Helen Anderson, Anita K. Dunbier, Neill Patani
Purpose: Endocrine therapies include aromatase inhibitors and the selective estrogen receptor (ER) downregulator fulvestrant. This study aimed to determine whether the reported efficacy of fulvestrant over anastrozole, and high- over low-dose fulvest
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5014894e906ae8400628ba07959eb66c
https://doi.org/10.1158/1078-0432.c.6522078
https://doi.org/10.1158/1078-0432.c.6522078
Autor:
Byung Lan Lee, Robert Wellings, Hee Sung Kim, Darren Hodgson, Christopher Womack, Woo Ho Kim, Seok-Ah Im, Mi-Na Kim, Xiaolu Yin, Mark J. O'Connor, Christopher George Harbron, Yung-Jue Bang
Publikováno v:
Pathobiology. 80:127-137
ATM (ataxia telangiectasia mutated) is one of several DNA repair proteins that are suggested to sensitize tumor cells to the poly(ADP-ribose) polymerase inhibitor olaparib when deficient. The aim of this study was to assess the spatiotemporal concord