Zobrazeno 1 - 10
of 104
pro vyhledávání: '"Robert Wattiaux"'
Publikováno v:
OENO One, Vol 34, Iss 4, Pp 177-180 (2000)
Several observations suggest that wine consumption could have beneficial effects on health by preventing cardiovascular diseases. Apparently, ethanol is not the only component responsible for these effects, phenolic substances: tanins, flavonoids may
Externí odkaz:
https://doaj.org/article/8a189bfdaae74a8980e5f5f665dd3691
Autor:
J. Mertens-Strijthagen, Simone Wattiaux-De Coninck, Michel Jadot, Jacqueline Thirion, Bruno Flamion, Robert Wattiaux, Marie-Christine Gasingirwa
Publikováno v:
Biochemical Journal
Biochemical Journal, Portland Press, 2010, 430 (2), pp.305-313. ⟨10.1042/BJ20100711⟩
Biochemical Journal, Portland Press, 2010, 430 (2), pp.305-313. ⟨10.1042/BJ20100711⟩
It has been suggested that intracellular Hyal-1 (hyaluronidase-1), which is considered a lysosomal enzyme, originates via endocytosis of the serum enzyme. To test this proposal we have investigated the uptake and intracellular distribution of rhHyal-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18e97d2b97f080c25fbecae356a89341
https://doi.org/10.1042/BJ20100711
https://doi.org/10.1042/BJ20100711
Autor:
Simone Wattiaux-De Coninck, Marie Christine Gasingirwa, Robert Wattiaux, Michel Jadot, Jacqueline Thirion
Publikováno v:
Biochemical Journal
Biochemical Journal, Portland Press, 2006, 403 (1), pp.89-95. ⟨10.1042/BJ20061738⟩
Biochemical Journal, Portland Press, 2006, 403 (1), pp.89-95. ⟨10.1042/BJ20061738⟩
International audience; A number of studies, mostly performed « ex vivo », suggest that lysosomes are involved in apoptosis as a result of a release of their cathepsins into the cytosol. These enzymes could then be contributing to the permeabilizat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8bb740d65ec99cab69f5da06111d3d98
https://doi.org/10.1042/bj20061738
https://doi.org/10.1042/bj20061738
Autor:
Michèle Lecocq, Fanjam Andrianaivo, Robert Wattiaux, Michel Jadot, Simone Wattiaux-De Coninck
Publikováno v:
The Journal of Gene Medicine. 6:877-883
Background The mechanism of gene transfer into hepatocytes by the hydrodynamics-based transfection procedure is not clearly understood. It has been shown that, after a hydrodynamic injection, a large proportion of plasmid DNA remains intact in the li
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6494ff1f6402df3ea079913173d118a2
https://doi.org/10.1002/jgm.574
https://doi.org/10.1002/jgm.574
Publikováno v:
Biochemical and Biophysical Research Communications. 319:1299-1306
Intravenous injection of gelonin and deglycosylated gelonin led to rapid clearance from the blood. Both molecules distributed similarly in liver and kidney suggesting that they followed the same pathway. Deglycosylation reduced the uptake by a third
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d3bd6053937445109d1605f04aca8114
https://doi.org/10.1016/j.bbrc.2004.05.117
https://doi.org/10.1016/j.bbrc.2004.05.117
Publikováno v:
European Journal of Biochemistry. 268:1392-1399
The cholesterol complexing agent methyl-cyclodextrin (MCD) provides an efficient mean for the removal of cholesterol from biological membranes. In order to study the effects of this agent on the lysosomal membrane in situ, we treated HepG2 cells with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6ff4de29303e826e6d5ea77cd4b7cf08
https://doi.org/10.1046/j.1432-1327.2001.02006.x
https://doi.org/10.1046/j.1432-1327.2001.02006.x
Autor:
David E. Sleat, Peter Lobel, Michel Jadot, Robert Wattiaux, Anthony H. Fensom, Marie T. Vanier, Saule Naureckiene, Henry Lackland
Publikováno v:
Science. 290:2298-2301
Niemann-Pick type C2 disease (NP-C2) is a fatal hereditary disorder of unknown etiology characterized by defective egress of cholesterol from lysosomes. Here we show that the disease is caused by a deficiency in HE1, a ubiquitously expressed lysosoma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3fbc175aaab34e7a8d3cbaa5766c1718
https://doi.org/10.1126/science.290.5500.2298
https://doi.org/10.1126/science.290.5500.2298
Publikováno v:
Biochemical and Biophysical Research Communications. 278:414-418
Branched polyamines are extensively used as nonviral vectors for plasmid DNA in transfection experiments. Moreover, recently it has been shown that these compounds are able to eliminate prions from infected cells in cultures. It has been proposed tha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f595eedc2e804874d6c41e612a39d046
https://doi.org/10.1006/bbrc.2000.3809
https://doi.org/10.1006/bbrc.2000.3809
Autor:
David E. Sleat, Peter Lobel, Li Lin, Istvan Sohar, Robert Wattiaux, Ming Sing Hsu, Franz Dubois, Michel Jadot, John E. Pintar, Simone Wattiaux-De Coninck
Publikováno v:
The Journal of Biological Chemistry. 274(30):21104-21113
The intracellular transport of soluble lysosomal enzymes relies on the post-translational modification of N-linked oligosaccharides to generate mannose 6-phosphate (Man 6-P) residues. In most cell types the Man 6-P signal is rapidly removed after tar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e3b289b63a3294a935f62628e57af096
https://researchportal.unamur.be/en/publications/4d4d6580-685c-4ac9-ae78-a98d48a4febc
https://researchportal.unamur.be/en/publications/4d4d6580-685c-4ac9-ae78-a98d48a4febc
Publikováno v:
Experimental Cell Research. 242(1):144-152
We have studied the localization of mutant cystic fibrosis transmembrane regulator delta F508CFTR in pancreatic adenocarcinoma cells (CFPAC), which naturally express the mutant protein. Our goal was to investigate whether delta F508CFTR is strictly r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71e1a42f4c4191b7a341aab94e5d4e36
https://researchportal.unamur.be/en/publications/ac581945-6ce1-417e-8518-c16c95592dab
https://researchportal.unamur.be/en/publications/ac581945-6ce1-417e-8518-c16c95592dab