Výsledky vyhledávání - "Robert Walls"

Akademický článek

Use of Patient Health Records to Quantify Drug-Related Pro-arrhythmic Risk

Autor: Mark R. Davies, Michael Martinec, Robert Walls, Roman Schwarz, Gary R. Mirams, Ken Wang, Guido Steiner, Andy Surinach, Carlos Flores, Thierry Lavé, Thomas Singer, Liudmila Polonchuk

Publikováno v: Cell Reports Medicine, Vol 1, Iss 5, Pp 100076- (2020)

Summary: There is an increasing expectation that computational approaches may supplement existing human decision-making. Frontloading of models for cardiac safety prediction is no exception to this trend, and ongoing regulatory initiatives propose us

Externí odkaz: https://doaj.org/article/8ab556035a2b4ff38523463e38599500

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Impact of Immune Checkpoint Inhibitors on COVID-19 Severity in Patients with Cancer

Autor: Ruoding Tan, Cindy Yun, Arpamas Seetasith, Daniel Sheinson, Robert Walls, Innocent Ngwa, Josina C Reddy, Qing Zhang, Matthew H Secrest, Peter Lambert, Khaled Sarsour

Publikováno v: The Oncologist. 27:236-243

Background Amid continued uncertainty about the management of cancer patients during the pandemic, this study sought to obtain real-world data on the use of immune checkpoint inhibitors (ICIs) before COVID-19 diagnosis and its association with severi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a12940e12962f5906750416306b1e96
https://doi.org/10.1093/oncolo/oyab083

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Use of Patient Health Records to Quantify Drug-Related Pro-arrhythmic Risk

Autor: Roman Schwarz, Andy Surinach, Robert Walls, Michael Martinec, Guido Steiner, Thierry Lavé, Liudmila Polonchuk, Mark R. Davies, Thomas Singer, Gary R. Mirams, Carlos Flores, Ken Wang

Publikováno v: Cell Reports Medicine, Vol 1, Iss 5, Pp 100076-(2020)
Cell Reports Medicine

Summary There is an increasing expectation that computational approaches may supplement existing human decision-making. Frontloading of models for cardiac safety prediction is no exception to this trend, and ongoing regulatory initiatives propose use

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::224b7222a23bc35d0395d3d3ff1fc1d8
http://www.sciencedirect.com/science/article/pii/S2666379120300975

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C-type lectin, hellercetin, negatively regulates melanoma cell adhesion and increases permeability

Autor: Montamas Suntravat, Jonathan Ortegon, Shelby Szteiter, Robert Walls, Elda E. Sánchez, Jacob A. Galan

Publikováno v: Toxicon. 159:S15

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::98cc81bad46795da34190c6f046ec7c1
https://doi.org/10.1016/j.toxicon.2018.11.367

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Functional characterizations of venom phenotypes in the eastern diamondback rattlesnake (Crotalus adamanteus) and evidence for expression-driven divergence in toxic activities among populations

Autor: Mark J. Margres, Elda E. Sánchez, Darin R. Rokyta, Montamas Suntravat, Robert Walls, Sara Lucena

Publikováno v: Toxicon : official journal of the International Society on Toxinology. 119

Phenotypes frequently vary across and within species. The connection between specific phenotypic effects and function, however, is less understood despite being essential to our understanding of the adaptive process. Snake venoms are ideal for identi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f31feee6223fcc08aaa31245489b0d4
https://pubmed.ncbi.nlm.nih.gov/27179420

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Impact of varying outcomes and definitions of suicidality on the associations of antiepileptic drugs and suicidality:comparisons from UK Clinical Practice Research Datalink (CPRD) and Danish national registries (DNR)

Autor: Jakob Christensen, Yolanda Alvarez, Ulrik Hesse, Robert Walls, Ole Mors, Raymond G. Schlienger, Mark C.H. De Groot, Olaf H. Klungel, Frank de Vries, Christiane Gasse, Robert F. Reynolds, Markus Schuerch, Noah Jamie Robinson

Publikováno v: Schuerch, M, Gasse, C, Robinson, N J, Alvarez, Y, Walls, R, Mors, O, Christensen, J, Hesse, U, de Groot, M, Schlienger, R, Reynolds, R, Klungel, O & de Vries, F 2016, ' Impact of varying outcomes and definitions of suicidality on the associations of antiepileptic drugs and suicidality : comparisons from UK Clinical Practice Research Datalink (CPRD) and Danish national registries (DNR) ', Pharmacoepidemiology and Drug Safety, vol. 25, no. Supplement S1, pp. 142-55 . https://doi.org/10.1002/pds.3928
Pharmacoepidemiology and Drug Safety, 25(Suppl 1), 142-155. Wiley
Pharmacoepidemiology and Drug Safety, 25(S1), 142. John Wiley and Sons Ltd
Pharmacoepidemiology and Drug Safety, 25(Suppl S1), 142. John Wiley and Sons Ltd

PURPOSE: The purpose of this study is to quantify the impact of the different outcomes and definitions of suicidality on the association between antiepileptic drugs (AEDs) and suicidality.METHODS: Retrospective cohort studies of selected AEDs (carbam

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d6028632aaf149693f6c0b34fc2e6400
https://pure.au.dk/portal/da/publications/impact-of-varying-outcomes-and-definitions-of-suicidality-on-the-associations-of-antiepileptic-drugs-and-suicidality(715e9c33-75a5-49c8-b245-e5b356bc883e).html

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Biological and biochemical characterization of venom from the broad-banded copperhead (Agkistrodon contortrix laticinctus): isolation of two new dimeric disintegrins

Autor: Elda E. Sánchez, Andrea Alfonso, Montamas Suntravat, Robert Walls, Alexis Rodríguez-Acosta, Sara Lucena, Amber Goins, Belsy Guerrero

Disintegrins represent a family of effective cell-cell and cell-matrix inhibitors by binding to integrin receptors. Integrins are heterodimeric, transmembrane receptors that are the bridges for these cell interactions. Disintegrins have been shown to

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a7ba9044b543f2fa71728e0cbc6bdb52
https://europepmc.org/articles/PMC5235361/

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The characterization of trans-pecos copperhead (Agkistrodon contortrix pictigaster) venom and isolation of two new dimeric disintegrins

Autor: Ifunanya Ogbata, Néstor L. Uzcátegui, Elda E. Sánchez, Alexis Rodríguez-Acosta, Elyse Grilli, Montamas Suntravat, Amber Goins, Andrea Alfonso, Robert Walls, Belsy Guerrero, Sara Lucena

Publikováno v: Biologicals : journal of the International Association of Biological Standardization. 44(4)

The vast amounts of toxins within the venom of snakes, while known to cause medical emergencies, display various biological functions. Trans-pecos copperhead (Agkistrodon contortrix pictigaster) crude venom separated by cation-exchange chromatography

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d9979dd89f031dcffbb04380e12c69ad
https://pubmed.ncbi.nlm.nih.gov/27068364

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A European inventory of data elements for patient recruitment

Autor: Justin, Doods, Caroline, Lafitte, Nadine, Ulliac-Sagnes, Johan, Proeve, Florence, Botteri, Robert, Walls, Andy, Sykes, Martin, Dugas, Fleur, Fritz

Publikováno v: Studies in health technology and informatics. 210

In the last few years much work has been conducted in creating systems that support clinical trials for example by utilizing electronic health record data. One of these endeavours is the Electronic Health Record for Clinical Research project (EHR4CR)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::4afd87b8b6a32de0ddf7b5e11161c573
https://pubmed.ncbi.nlm.nih.gov/25991199

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