Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Robert W. Zajdel"'
Publikováno v:
Journal of Cellular Biochemistry. 95:840-848
Striated muscle tropomyosin (TM) is described as containing ten exons; 1a, 2b, 3, 4, 5, 6b, 7, 8, and 9a/b. Exon 9a/b has critical troponin binding domains and is found in striated muscle isoforms. We have recently discovered a smooth (exon 2a)/stria
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a022c4f25d0dfc111403bf710fa9827
https://doi.org/10.1002/jcb.20456
https://doi.org/10.1002/jcb.20456
Autor:
Masako Nakatsugawa, Dipak K. Dube, Aruna Narshi, Bernard J. Poiesz, Syamalima Dube, Robert W. Zajdel, Christopher R. Denz
Publikováno v:
Cardiovascular Toxicology. 5:001-008
Although the role of tropomyosin is well-defined in striated muscle, the precise mechanism of how tropomyosin functions is still unclear. It has been shown that extension of either N- or C-terminal ends of sarcomeric tropomyosin do not affect cardiac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7fc3eb50faddbf1560f118859aea0329
https://doi.org/10.1385/ct:5:1:001
https://doi.org/10.1385/ct:5:1:001
Autor:
Chi Zhang, Robert W. Zajdel, Xupei Huang, Dipak K. Dube, Dalton Foster, Larry F. Lemanski, Sharon L. Lemanski, Rajula Bhatia
Publikováno v:
Anatomy and Embryology. 206:495-506
Ambystoma mexicanum is an intriguing animal model for studying heart development because it carries a mutation in gene c. Hearts of homozygous recessive (c/c) mutant embryos do not contain organized myofibrils and fail to beat. The defect can be corr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::213048bf9c51f042827b3c79f46421a6
https://doi.org/10.1007/s00429-003-0315-8
https://doi.org/10.1007/s00429-003-0315-8
Autor:
Belinda J. Spinner, Nancy Dobbins, Matthew D. McLean, Dipak K. Dube, Larry F. Lemanski, Christopher R. Denz, Robert W. Zajdel, Aruna Choudhury, Masako Nakatsugawa, Syamalima Dube, Sonali Mehta
Publikováno v:
Journal of Cellular Biochemistry. 85:747-761
A striated muscle isoform of a Tropomyosin (TM-4) gene was characterized and found to be necessary for contractile function in embryonic heart. The full-length clone of this isoform was isolated from the Mexican axolotl (Ambystoma mexicanum) and name
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e5e384f6d10291e2620b693be6e67a3f
https://doi.org/10.1002/jcb.10178
https://doi.org/10.1002/jcb.10178
Autor:
Douglas R. Robertson, Christopher R. Denz, Dipak K. Dube, Robert W. Zajdel, Larry F. Lemanski, Arun Gaur, Gulbu Isitmangil, Rajula Bhatia
Publikováno v:
Cardiovascular Toxicology. 1:225-236
Widespread external and internal changes in body morphology have long been known to be hallmarks of the process of metamorphosis. However, more subtle changes, particularly at the molecular level, are only now beginning to be understood. A number of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::72ef831a1df5452660d13129f0ab3dfe
https://doi.org/10.1385/ct:1:3:225
https://doi.org/10.1385/ct:1:3:225
Publikováno v:
Experimental Cell Research. 248:557-566
Hearts from cardiac mutant Mexican axolotl, Ambystoma mexicanum, do not form organized myofibrils and fail to beat. Though previous biochemical and immunohistochemical experiments showed a possible reduction of cardiac tropomyosin it was not clear th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a2278a32f26f06bfeb57560afd491d14
https://doi.org/10.1006/excr.1999.4419
https://doi.org/10.1006/excr.1999.4419
Autor:
David F. Wieczorek, Larry F. Lemanski, Matthew D. McLean, Sharon L. Lemanski, Robert W. Zajdel, Mariappan Muthuchamy, Dipak K. Dube
Publikováno v:
Developmental Dynamics. 213:412-420
Expression of tropomyosin protein, an essential component of the thin filament, has been found to be drastically reduced in cardiac mutant hearts of the Mexican axolotl (Ambystoma mexicanum) with no formation of sarcomeric myofibrils. Therefore, this
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::029a7b8b956adf3f2085c99722b711ca
https://doi.org/10.1002/(sici)1097-0177(199812)213:4<412::aid-aja6>3.0.co
https://doi.org/10.1002/(sici)1097-0177(199812)213:4<412::aid-aja6>3.0.co
Publikováno v:
In Vitro Cellular & Developmental Biology - Animal. 33:677-680
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a4d7b35c8d5e03f02a3b9b1e83ceb4b
https://doi.org/10.1007/s11626-997-0124-0
https://doi.org/10.1007/s11626-997-0124-0
Publikováno v:
Journal of Clinical & Experimental Cardiology.
Copyright: © 2013 Dubev DK, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5d398d476cdd53dd70e17cde8027e71b
https://doi.org/10.4172/2155-9880.1000e132
https://doi.org/10.4172/2155-9880.1000e132
Autor:
Jean M. Sanger, Mary Otoo, Arun Rajan, Mingda Han, Harold L. Thurston, Syamalima Dube, Dipak K. Dube, Jushuo Wang, Joseph W. Sanger, Kersti K. Linask, Robert W. Zajdel, Eugene Essandoh
Publikováno v:
Cell motility and the cytoskeleton. 65(5)
The expression of striated muscle proteins occurs early in the developing embryo in the somites and forming heart. A major component of the assembling myofibrils is the actin-binding protein tropomyosin. In vertebrates, there are four genes for tropo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ecfab7ff56632e7d087307d328a53ac4
https://pubmed.ncbi.nlm.nih.gov/18302173
https://pubmed.ncbi.nlm.nih.gov/18302173