Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Robert W. Schroff"'
Autor:
John E. Taylor, Michael D. Culler, Thurieau Christophe Alain, Caroline Touvay, Elaine McKilligin, Robert W. Schroff, Jesse Z. Dong
Publikováno v:
Mini-Reviews in Medicinal Chemistry. 5:849-855
The dividing line between essential physiological inflammatory processes and excessive pathological inflammation is often very thin - in some circumstances, indeed, it may be non-existent. Devising anti-inflammatory medications that effectively targe
Autor:
Lawrence L. Kunz, Robert W. Schroff
Publikováno v:
Gene Transfer in the Cardiovascular System ISBN: 9781461378815
There are presently a number of applications for gene therapy, and a number of promising approaches. This chapter describes a variety of methodologies that could potentially be employed to address some of the deficiencies of current delivery vehicles
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::62868037c92c4252dbf40b6b647159d9
https://doi.org/10.1007/978-1-4615-6277-1_9
https://doi.org/10.1007/978-1-4615-6277-1_9
Publikováno v:
Journal of the American College of Cardiology. 25(2)
The predominant role of geometric remodeling in restenosis after percutaneous coronary angioplasty (PTCA) has recently been described. In this study, Cytochalasin B (CB), a compound which reversibly blocks actin polymerization and thereby inhibits sm
Publikováno v:
Blood. 60:1-19
Recent advances in immunology have led to important insights into leukocyte differentiation and the cellular origin of leukemia. It is now possible to precisely define stages of human lymphocyte and granulocyte differentiation utilizing highly specif
Publikováno v:
Blood. 59:207-215
A panel of monoclonal antibodies reactive with normal lymphocyte subsets was used to classify cases of lymphocytic leukemia on the basis of cell surface antigen expression. The antibodies employed were commercially available and included a common fra
Autor:
Michael S. Gottlieb, Robert A. Wolf, J.D. Weisman, Andrew Saxon, Robert W. Schroff, P.T. Fan, Howard M. Schanker
Publikováno v:
New England Journal of Medicine. 305:1425-1431
Four previously healthy homosexual men contracted Pneumocystis carinii pneumonia, extensive mucosal candidiasis, and multiple viral infections. In three of the patients these infections followed prolonged fevers of unknown origin. In all four cytomeg
Autor:
S L Giardina, N Pritikin, David W. Golde, RK Oldham, J Sklar, Kenneth A. Foon, Robert W. Schroff, ML Cleary, CS Woodhouse
Publikováno v:
Blood. 66:1017-1021
Immunoglobulin gene rearrangement analysis and somatic cell hybridization techniques were used to examine the malignant cell population in an unusual patient with hairy cell leukemia and macroglobulinemia (N Engl J Med 296:92, 1977). Although previou
Autor:
Paul G. Abrams, Clive S. Woodhouse, Kenneth A. Foon, Robert W. Schroff, Robert K. Oldham, A. Charles Morgan
Publikováno v:
Medical Oncology and Tumor Pharmacotherapy. 1:51-62
The need for improved specificity in cancer therapy is apparent. With the advent of monoclonal antibodies, the possibility of specifically targeted therapy is here. Early trials with monoclonal antibody in experimental animals and in man have demonst
Publikováno v:
Blood. 66:620-626
We have previously reported that the addition of monocytes results in enhanced modulation of the T65 antigen when normal or leukemic lymphoid cells were cultured in vitro with the T101 monoclonal antibody. In the present investigation, we extend thes
Autor:
J J Ochs, M Fer, Deborah K. Mayer, GC Bottino, Kenneth A. Foon, Paul G. Abrams, DJ Carlo, Paul A. Bunn, Robert W. Schroff, SA Sherwin
Publikováno v:
Blood. 64:1085-1093
A phase I clinical trial was initiated to treat patients with stage IV B-derived chronic lymphocytic leukemia (CLL) with the IgG2a murine monoclonal antibody T101. This antibody binds to a 65,000-mol wt (T65) antigen found on normal T lymphocytes, ma