Zobrazeno 1 - 10
of 128
pro vyhledávání: '"Robert W. Putnam"'
Publikováno v:
PLoS Computational Biology, Vol 13, Iss 12, p e1005853 (2017)
Central chemoreceptors are highly sensitive neurons that respond to changes in pH and CO2 levels. An increase in CO2/H+ typically reflects a rise in the firing rate of these neurons, which stimulates an increase in ventilation. Here, we present an io
Externí odkaz:
https://doaj.org/article/5810c4631db1416782c59a5b6ab53c05
Publikováno v:
PLoS ONE, Vol 9, Iss 2, p e88161 (2014)
NK1 receptors, which bind substance P, are present in the majority of brainstem regions that contain CO2/H(+)-sensitive neurons that play a role in central chemosensitivity. However, the effect of substance P on the chemosensitive response of neurons
Externí odkaz:
https://doaj.org/article/6e84fb8c1a564021bfa25ff996d3dc8d
Autor:
Ke-Yong Li, Luis Gustavo Alexandre Patrone, Luciane H. Gargaglioni, Ann N. Imber, Robert W. Putnam
Publikováno v:
Scopus
Repositório Institucional da UNESP
Universidade Estadual Paulista (UNESP)
instacron:UNESP
Repositório Institucional da UNESP
Universidade Estadual Paulista (UNESP)
instacron:UNESP
Made available in DSpace on 2018-12-11T17:20:03Z (GMT). No. of bitstreams: 0 Previous issue date: 2018-06-15 Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP) National Heart, Lung, and Blood Institute Wright State University The cellu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8483dbcc6e1e089845d5f7f98092e6b2
https://doi.org/10.1016/j.neuroscience.2018.03.031
https://doi.org/10.1016/j.neuroscience.2018.03.031
Publikováno v:
Neuroscience. 270:98-122
We tested the hypothesis that decreasing the control level of O2 from 95% to 40% reduces tissue partial pressure of oxygen (pO2), decreases extracellular nitric oxide ( NO) and decreases intracellular superoxide ( O2−) while maintaining viability i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2b65114346cc8a7f49e919fba418b4c5
https://doi.org/10.1016/j.neuroscience.2014.03.017
https://doi.org/10.1016/j.neuroscience.2014.03.017
Publikováno v:
American Journal of Physiology-Regulatory, Integrative and Comparative Physiology. 305:R1451-R1464
The locus coeruleus (LC) is a chemoreceptive brain stem region in anuran amphibians and contains neurons sensitive to physiological changes in CO2/pH. The ventilatory and central sensitivity to CO2/pH is proportional to the temperature in amphibians,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3aa13e23d2e30d370792a6ddf091b723
https://doi.org/10.1152/ajpregu.00348.2013
https://doi.org/10.1152/ajpregu.00348.2013
Autor:
Ryan W. Bavis, Ke-Yong Li, Ryan J. March, Sarah Logan, Kathryn J. DeAngelis, Josefine A. Wallace, Robert W. Putnam
Publikováno v:
Respiratory physiologyneurobiology. 237
Rats reared in hyperoxia hypoventilate in normoxia and exhibit progressive blunting of the hypoxic ventilatory response, changes which are at least partially attributed to abnormal carotid body development. Since the carotid body also responds to cha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::83a5b1f6b76cecc3fb397d93b3567e81
https://pubmed.ncbi.nlm.nih.gov/28034711
https://pubmed.ncbi.nlm.nih.gov/28034711
Autor:
Robert W. Putnam, Jay B. Dean
Publikováno v:
Respiratory Physiology & Neurobiology. 173:274-287
The solitary complex is comprised of the nucleus tractus solitarius (NTS, sensory) and dorsal motor nucleus of the vagus (DMV, motor), which functions as an integrative center for neural control of multiple systems including the respiratory, cardiova
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::96486cdb5ad862c12309062daab8521c
https://doi.org/10.1016/j.resp.2010.07.002
https://doi.org/10.1016/j.resp.2010.07.002
Publikováno v:
Journal of Applied Physiology. 109:804-819
Breathing hyperbaric oxygen (HBO) is common practice in hyperbaric and diving medicine. The benefits of breathing HBO, however, are limited by the risk of central nervous system O2 toxicity, which presents as seizures. We tested the hypothesis that e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7fe2ca1cac4ba2e1f82db635a86b8bc1
https://doi.org/10.1152/japplphysiol.91429.2008
https://doi.org/10.1152/japplphysiol.91429.2008
Autor:
Robert W. Putnam
Publikováno v:
Journal of Applied Physiology. 108:1796-1802
Considerable progress has been made elucidating the cellular signals and ion channel targets involved in the response to increased CO2/H+ of brain stem neurons from chemosensitive regions. Intracellular pH (pHi) does not exhibit recovery from an acid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf8a4a7ac8df113f87f5dc693ea3a8dd
https://doi.org/10.1152/japplphysiol.01169.2009
https://doi.org/10.1152/japplphysiol.01169.2009
pH regulating transporters in neurons from various chemosensitive brainstem regions in neonatal rats
Autor:
Robert W. Putnam, Avash Kalra, Lynn K. Hartzler, Anna E. Kersh, Brittany Belcastro Hubbell, Nick A. Ritucci, Jason Chua, Jay B. Dean, Vivian C. Nanagas, Kevin Havlin, Ryan Whitesell
Publikováno v:
American Journal of Physiology-Regulatory, Integrative and Comparative Physiology. 297:R1409-R1420
We studied the membrane transporters that mediate intracellular pH (pHi) recovery from acidification in brainstem neurons from chemosensitive regions of neonatal rats. Individual neurons within brainstem slices from the retrotrapezoid nucleus (RTN),
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::834cfeca8d5dcc2f51d0be8ff86b947f
https://doi.org/10.1152/ajpregu.91038.2008
https://doi.org/10.1152/ajpregu.91038.2008