Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Robert W. Price"'
Autor:
Maralyssa Bann, Brenda D. Moore, Neill R. Graff-Radford, Jungsu Kim, Fanggeng Zou, Lisa A. Smithson, Vijayaraghavan Rangachari, Dennis W. Dickson, Victor M. Miller, Terrone L. Rosenberry, Fredrick J. Troendle, Robert W. Price, Leilani K. Sonoda, Karen Jansen West, Christophe Verbeeck, Craig W. Zwizinski, Kayleigh Wagg, Yona Levites, Steven G. Younkin, Todd E. Golde
Publikováno v:
Journal of Neuroscience. 28:6030-6036
Analyses of the biologic effects of mutations in the BRI2 (ITM2b) and the amyloid β precursor protein (APP) genes support the hypothesis that cerebral accumulation of amyloidogenic peptides in familial British and familial Danish dementias and Alzhe
Autor:
Thomas B. Ladd, Bernadette Cusack, Debra Yager, Dominic M. Walsh, Thomas Kukar, Ghulam M. Maharvi, Robert Chapman, Alfred T. Welzel, Vijayaraghavan Rangachari, Christopher B. Eckman, Wenjuan Ye, Christophe Verbeeck, Sarah A. Sagi, Maralyssa Bann, Todd E. Golde, Robert W. Price, Terrone L. Rosenberry, Boris Schmidt, Justin W. Torpey, Brent Healy, Barbara A. Cottrell, Karen Jansen-West, Jason L. Eriksen, Edward H. Koo, Abdul H. Fauq, Patrick C. Fraering, Rajeshwar Narlawar, Michael S. Wolfe, Brenda D. Moore
Publikováno v:
Nature. 453:925-929
Selective lowering of Abeta42 levels (the 42-residue isoform of the amyloid-beta peptide) with small-molecule gamma-secretase modulators (GSMs), such as some non-steroidal anti-inflammatory drugs, is a promising therapeutic approach for Alzheimer's d
Publikováno v:
Echocardiography. 13:57-63
In this study, isovolumetric relaxation time (IVRT) flow velocities recorded by pulsed Doppler were induced or augmented in nine patients (aged 60 +/- 20 years) with permanent pacemakers. Six subjects had evidence of IVRT flow (/=0.2 m/sec) during na
Autor:
Vijayaraghavan Rangachari, Maralyssa Bann, V. Shane Pankratz, Steven G. Younkin, David J. Cangemi, Todd E. Golde, Fredrick J. Troendle, Karen Jansen-West, Yona Levites, Jungsu Kim, Christophe Verbeeck, Fanggeng Zou, Terrone L. Rosenberry, Victor M. Miller, Robert W. Price, Kayleigh Wagg, Li Ma, Craig W. Zwizinski, Dennis W. Dickson, Lisa A. Smithson, Samuel Younkin, Ronald C. Petersen, Brenda D. Moore, Leilani K. Sonoda
Publikováno v:
Alzheimer's & Dementia. 4
Autor:
Suzanne Randle, Craig W. Zwizinski, Luisa Onstead, Robert W. Price, Lisa A. Smithson, Dennis W. Dickson, Todd E. Golde, Eileen McGowan, Jungsu Kim
Numerous studies have established a pivotal role for Abeta42 in Alzheimer's disease (AD) pathogenesis. In contrast, although Abeta40 is the predominant form of amyloid beta (Abeta) produced and accumulates to a variable degree in the human AD brain,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a88df07d7645a01ce1493888efaac3b
https://europepmc.org/articles/PMC6672801/
https://europepmc.org/articles/PMC6672801/
Autor:
Yona Levites, Lisa A. Smithson, Robert W. Price, Rachel S. Dakin, Bin Yuan, Michael R. Sierks, Jungsu Kim, Eileen McGowan, Dana Kim Reed, Terrone L. Rosenberry, Pritam Das, Todd E. Golde
Publikováno v:
FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 20(14)
A number of hypotheses regarding how anti-Abeta antibodies alter amyloid deposition have been postulated, yet there is no consensus as to how Abeta immunotherapy works. We have examined the in vivo binding properties, pharmacokinetics, brain penetran
Autor:
Judith Wilson, Amanda Hanna, Robert W. Price, Jungsu Kim, Eileen McGowan, Dennis W. Dickson, Christopher Janus, Todd E. Golde
Publikováno v:
Alzheimer's & Dementia. 2
Autor:
Suzanne Randle, Eileen McGowan, Cindy Yu, Luisa Onstead, Lisa A. Smithson, Dennis W. Dickson, Todd E. Golde, Robert W. Price, Jungsu Kim
Publikováno v:
Alzheimer's & Dementia. 2
Autor:
Robert W. Price, Michael P. Murphy, Yona Levites, Marjorie J. Rochette, Lisa A. Kostura, Eileen McGowan, Pritam Das, Todd E. Golde
Accumulation and aggregation of amyloid beta peptide 1-42 (Abeta42) in the brain has been hypothesized as triggering a pathological cascade that causes Alzheimer disease (AD). To determine whether selective targeting of Abeta42 versus Abeta40 or tota
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a606abd5cfe1255fe046a7ff24a0575
https://europepmc.org/articles/PMC1307561/
https://europepmc.org/articles/PMC1307561/
Autor:
Robert W. Price
Publikováno v:
SAE Technical Paper Series.