Zobrazeno 1 - 10
of 73
pro vyhledávání: '"Robert W. Peoples"'
Autor:
Braulio Muñoz, Trinidad Mariqueo, Pablo Murath, Christian Peters, Gonzalo E. Yevenes, Gustavo Moraga-Cid, Robert W. Peoples, Luis G. Aguayo
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 14 (2021)
Alpha1-containing glycine receptors (GlyRs) are major mediators of synaptic inhibition in the spinal cord and brain stem. Recent studies reported the presence of α2-containing GlyRs in other brain regions, such as nucleus accumbens and cerebral cort
Externí odkaz:
https://doaj.org/article/a1e12b7b340445f3965359c8b8f2cef4
Autor:
Eduardo J. Fernández-Pérez, Fernando J. Sepúlveda, Christian Peters, Denisse Bascuñán, Nicolás O. Riffo-Lepe, Juliana González-Sanmiguel, Susana A. Sánchez, Robert W. Peoples, Benjamín Vicente, Luis G. Aguayo
Publikováno v:
Frontiers in Aging Neuroscience, Vol 10 (2018)
Background: The beta-amyloid peptide (Aβ) involved in Alzheimer’s disease (AD) has been described to associate/aggregate on the cell surface disrupting the membrane through pore formation and breakage. However, molecular determinants involved for
Externí odkaz:
https://doaj.org/article/c0d52c8ea990403dbddd559f6d98363d
Publikováno v:
Neurobiology of Disease, Vol 25, Iss 2, Pp 360-366 (2007)
The idea that the environmental toxin β-N-methylamino-l-alanine (BMAA) is involved in neurodegenerative diseases on Guam has risen and fallen over the years. The theory has gained greater interest with recent reports that BMAA is biomagnified, is wi
Externí odkaz:
https://doaj.org/article/a31e5a8c2f6945dd87d225411e861cd6
Publikováno v:
Alcohol Clin Exp Res
BACKGROUND: Alcohol alters synaptic transmission in the brain. The N-methyl-D-aspartate (NMDA) receptor, a subtype of glutamate-gated ion channel, is an important synaptic target of alcohol in the brain. We and others have previously identified four
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9181ba8d3db4984517ea58e7e580346f
https://pubmed.ncbi.nlm.nih.gov/30964201
https://pubmed.ncbi.nlm.nih.gov/30964201
Publikováno v:
British Journal of Pharmacology. 173:1950-1965
Background and purpose The NMDA receptor is an important target of alcohol action in the brain. Recent studies in this laboratory have demonstrated that alcohol-sensitive positions in the intersubunit interfaces of the M3 and M4 domains of GluN1 and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::614213b53d4c8d48d25f3c818c6f35de
https://doi.org/10.1111/bph.13487
https://doi.org/10.1111/bph.13487
Autor:
Benjamín Vicente, Nicolas O Riffo-Lepe, Juliana González-Sanmiguel, Eduardo J Fernández-Pérez, Christian Peters, Fernando J. Sepúlveda, Denisse Bascuñán, Luis G. Aguayo, Robert W. Peoples, Susana A. Sanchez
Publikováno v:
Frontiers in Aging Neuroscience
Frontiers In Aging Neuroscience
Artículos CONICYT
CONICYT Chile
instacron:CONICYT
Frontiers in Neuroscience
Frontiers in Aging Neuroscience, Vol 10 (2018)
Frontiers In Aging Neuroscience
Artículos CONICYT
CONICYT Chile
instacron:CONICYT
Frontiers in Neuroscience
Frontiers in Aging Neuroscience, Vol 10 (2018)
Background: The beta-amyloid peptide (Aβ) involved in Alzheimer’s disease (AD) has been described to associate/aggregate on the cell surface disrupting the membrane through pore formation and breakage. However, molecular determinants involved for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::341a75516dfa7081f917a0122733e0ed
https://doi.org/10.3389/fnagi.2018.00226
https://doi.org/10.3389/fnagi.2018.00226
Autor:
C. Strother, S. Urban, Robert W. Peoples, C. Kuehn, M. Jessick, E. Bauer, S. Franczak, L. Schraufnagel, E. Fricker, L. Thota, Stacey Strandberg, A. Griffith‐Topps, C. Lois, J. Strother, C. Sargent, S. Strandberg, Scott Fleischmann
Publikováno v:
The FASEB Journal. 32
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a4c59ab1e017600b908fd723c6159b7f
https://doi.org/10.1096/fasebj.2018.32.1_supplement.lb204
https://doi.org/10.1096/fasebj.2018.32.1_supplement.lb204
Publikováno v:
Neuropharmacology. 97:240-250
The NMDA receptor is a major target of alcohol action in the CNS, and recent behavioral and cellular studies have pointed to the importance of the GluN2B subunit in alcohol action. We and others have previously characterized four amino acid positions
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::628615379353c0c475db9454acf56ff4
https://doi.org/10.1016/j.neuropharm.2015.05.018
https://doi.org/10.1016/j.neuropharm.2015.05.018
Publikováno v:
Biochimica Et Biophysica Acta-Molecular Basis Of Disease
Artículos CONICYT
CONICYT Chile
instacron:CONICYT
Artículos CONICYT
CONICYT Chile
instacron:CONICYT
The ability of beta-amyloid peptide (Aβ) to disrupt the plasma membrane through formation of pores and membrane breakage has been previously described. However, the molecular determinants for these effects are largely unknown. In this study, we exam
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6bc7db2f9aebaefe18b3e9f9bb630521
https://pubmed.ncbi.nlm.nih.gov/28844949
https://pubmed.ncbi.nlm.nih.gov/28844949
Autor:
Chaoying Li, Keming Xiong, Yuwei Liu, Lin Chen, Chu-Li Yi, Robert W. Peoples, Yuxiang Wu, Randall R. Stewart
Publikováno v:
European Journal of Pharmacology. 707:11-16
One feature of the amino acid sequence of P2X receptors identified from mammalian species, Xenopus laevis and zebrafish is the conservation of ten cysteines in the extracellular loop. Little information is available about the role of these conserved
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::66c978f9c4695721bce6fc2fd0fe7cdf
https://doi.org/10.1016/j.ejphar.2013.03.011
https://doi.org/10.1016/j.ejphar.2013.03.011