Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Robert W. Oberfelder"'
Publikováno v:
Biochemistry. 23:3813-3821
The mechanism of allosteric regulation of rabbit muscle pyruvate kinase (PK) was examined in the presence of the allosteric inhibitor phenylalanine (Phe). Steady-state kinetic, equilibrium binding, and structural studies were conducted to provide a b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1255931192cccf730bfd05df1033a959
https://doi.org/10.1021/bi00312a004
https://doi.org/10.1021/bi00312a004
Publikováno v:
Biochemistry. 23:3822-3826
A concerted, allosteric model is developed, and equations are derivsd for quantitative interpretation of the kinetic and equilibrium binding data of rabbit muscle pyruvate kinase at pH 7.5 and 23 OC. The simplest model which seems likely to rationali
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c8088e06dd2c132e731fc2ce862b2d28
https://doi.org/10.1021/bi00312a005
https://doi.org/10.1021/bi00312a005
Publisher Summary This chapter discusses measurement of changes of hydrodynamic properties by sedimentation. To define accurately the conformational change in question, and to differentiate between local and global structural change, the overall pict
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d1f14c543724bcea1696772f122c3497
https://doi.org/10.1016/s0076-6879(85)17004-7
https://doi.org/10.1016/s0076-6879(85)17004-7
Autor:
James Lee, Robert W. Oberfelder
Publisher Summary Determination of the equilibrium binding constant and the stoichiometry for a protein-ligand interaction requires an appropriate choice of methodology. Each technique has advantages and disadvantages, and practical and theoretical l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::80e7e9ae281561db52b18105a0678f05
https://doi.org/10.1016/s0076-6879(85)17023-0
https://doi.org/10.1016/s0076-6879(85)17023-0