Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Robert W. McGuffin"'
Publikováno v:
PharmacoEconomics. 9:134-145
Alcohol (ethanol) use disorders are prevalent in many countries and are associated with significant social and health costs. Little is known, however, about the comparative cost effectiveness of treatments for alcoholism. Pharmacoeconomic evaluations
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd66664d0510de00e85d643b823bcf31
https://doi.org/10.2165/00019053-199609020-00005
https://doi.org/10.2165/00019053-199609020-00005
Publikováno v:
Biochemical Pharmacology. 44:1917-1920
The human 5-HT 1Ds serotonin receptor and its rat homolog (also called the 5-HT 1B receptor) share 93% amino acid identity, yet display markedly different pharmacological specificities. Comparison of deduced amino acid sequences among these and other
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ffad3b3a05d6fe309464c63797a821a8
https://doi.org/10.1016/0006-2952(92)90092-w
https://doi.org/10.1016/0006-2952(92)90092-w
Publikováno v:
Biochemical and Biophysical Research Communications. 184:752-759
We describe a genomic clone encoding the human 5-HT1B receptor. This apparently intronless gene encodes a 390 amino acid polypeptide homologous to the rat 5-HT1B serotonin receptor, with which it shares 93% amino acid sequence identity. Remarkably, [
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::66884b7a4befced5b7bb47eb1b452f80
https://doi.org/10.1016/0006-291x(92)90654-4
https://doi.org/10.1016/0006-291x(92)90654-4
Publikováno v:
Journal of substance abuse treatment. 14(4)
An open trial of transdermal nicotine replacement for smoking cessation was conducted. Over a 7-month period, all patients admitted to the inpatient alcohol and drug treatment unit of the Seattle Veterans Affairs Medical Center, (n = 207) were offere
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e648d239239592fdc6fff154d5aacd09
https://pubmed.ncbi.nlm.nih.gov/9368209
https://pubmed.ncbi.nlm.nih.gov/9368209
Publikováno v:
Molecular and cellular neurosciences. 3(6)
We and others have recently cloned the genes encoding the human 5-HT(1D) (5-HT(1Dalpha)) and 5-HT(1B) (5-HT(1Dbeta)) serotonin receptors. Because of the history of profound species differences in the pharmacology of these receptor subtypes, we also c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::acbd95181aa0394e2705093f3cd32fa0
https://pubmed.ncbi.nlm.nih.gov/19912901
https://pubmed.ncbi.nlm.nih.gov/19912901
Autor:
Philip J. Fialkow, Robert W. McGuffin, John R. Neefe, Ronald A. Sacher, Robert Jacobson, Jack W. Singer
Publikováno v:
Blood. 56:70-73
It has been shown with glucose 6-phosphate dehydrogenase (G-6-PD) mosaicism that Ph1-positive chronic myelogenous leukemia (CML) is a clonal disease that involves multipotent hematopoietic stem cells. We now report G-6-PD studies of a 79-yr-old woman
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a5dd9f4e49098f9e88dc34a9b1e63dad
https://doi.org/10.1182/blood.v56.1.70.70
https://doi.org/10.1182/blood.v56.1.70.70
Autor:
Robert W. McGuffin, A Keating, Jean E. Sanders, R Ramberg, J. W. Singer, P. J. Fialkow, George E. Sale, Thomas Ed
Publikováno v:
Scopus-Elsevier
This article describes the course of a patient who received an allogeneic marrow graft from his HLA-identical sister for acute lymphoblastic leukemia in second remission. In the second month after grafting, marrow aspirates showed the presence of 7%-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c62ae0d12ba983a1ad1392b1e5f792bf
https://doi.org/10.1182/blood.v62.4.869.bloodjournal624869
https://doi.org/10.1182/blood.v62.4.869.bloodjournal624869
Publikováno v:
Journal of Antimicrobial Chemotherapy. 12:181-193
Despite the lack of virus-specified thymidine kinase activity, human cytomegalovirus may be sensitive to acyclovir in vitro at concentrations between 10 and 25 mg/l. The inhibitory effect of acyclovir can be further increased by the presence of small
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6bf59207fb6aa76dbf052245a7d39da4
https://doi.org/10.1093/jac/12.suppl_b.181
https://doi.org/10.1093/jac/12.suppl_b.181
Publikováno v:
Journal of Infectious Diseases. 146:80-84
Seven marrow transplant recipients were treated with human leukocyte interferon and vidarabine for cytomegalovirus pneumonia. Although the mean virus titer in biopsy and autopsy lung specimens from five patients decreased from 5 x 10(4) to 1 x 10(2)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f261fef4f0b4ae0e22278fbedd48bda6
https://doi.org/10.1093/infdis/146.1.80
https://doi.org/10.1093/infdis/146.1.80
Autor:
James D. Connor, James C. Wade, Robert W. McGuffin, Marie A. Hintz, Steven C. Springmeyer, Joel D. Meyers
Publikováno v:
The American Journal of Medicine. 73:249-256
Cytomegalovirus pneumonia is a serious complication of marrow transplantation, with a 90 percent fatality rate. Acyclovir, a new antiviral agent with variable in vitro activity against cytomegalovirus, was administered to eight marrow transplant pati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::90b826b5e92e07f6db7bd1a01d48cb13
https://doi.org/10.1016/0002-9343(82)90100-0
https://doi.org/10.1016/0002-9343(82)90100-0