Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Robert W. Link"'
Autor:
Will Dampier, Robert W. Link, Joshua P. Earl, Mackenzie Collins, Diehl R. De Souza, Kelvin Koser, Michael R. Nonnemacher, Brian Wigdahl
Publikováno v:
Frontiers in Virology, Vol 2 (2022)
The human immunodeficiency virus type 1 (HIV-1) is a global health threat that is characterized by extensive genetic diversity both within and between patients, rapid mutation to evade immune controls and antiretroviral therapies, and latent cellular
Externí odkaz:
https://doaj.org/article/c805edf8da864e5c85df36ae9c98a0b5
Autor:
Robert W. Link, Diehl R. De Souza, Cassandra Spector, Anthony R. Mele, Cheng-Han Chung, Michael R. Nonnemacher, Brian Wigdahl, Will Dampier
Publikováno v:
Frontiers in Virology, Vol 2 (2022)
Accounting for genetic variation is an essential consideration during human immunodeficiency virus type 1 (HIV-1) investigation. Nanopore sequencing preserves proviral integrity by passing long genomic fragments through ionic channels, allowing reads
Externí odkaz:
https://doaj.org/article/b676a6913bc4468e80a81ca26ae87455
Autor:
Cheng-Han Chung, Alexander G. Allen, Andrew Atkins, Robert W. Link, Michael R. Nonnemacher, Will Dampier, Brian Wigdahl
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 11 (2021)
Clustered regularly interspaced short palindromic repeats (CRISPR)-based HIV-1 genome editing has shown promising outcomes in in vitro and in vivo viral infection models. However, existing HIV-1 sequence variants have been shown to reduce CRISPR-medi
Externí odkaz:
https://doaj.org/article/ea35d33ad04a48eaa63b98608e3704b4
Publikováno v:
The CRISPR Journal. 1:294-302
Chronic human immunodeficiency virus type 1 (HIV-1) disease is characterized by the retention of provirus within latently infected cells. Anti-HIV-1 CRISPR-Cas9 gene editing is an attractive strategy to excise or inactivate the HIV-1 genome. Recent s
Autor:
Robert W. Link, Jeffrey M. Jacobson, Kim Malone, Gregory C. Antell, Will Dampier, Shendra Passic, Katherine Kercher, Anthony R. Mele, Brian Wigdahl, Wen Zhong, Zsofia Szep, Vanessa Pirrone, Michael R. Nonnemacher
Publikováno v:
Virus Res
Human immunodeficiency virus type 1 (HIV-1) encodes for Tat, a multi-functional regulatory protein involved in transcriptional enhancement and in causing neurotoxicity/central nervous system (CNS) dysfunction. This study examines Sanger sequencing of
Publikováno v:
Expert Review of Vaccines, Vol 16, Iss 12, Pp 1203-1216 (2017)
Introduction: In 1988, an estimated 350,000 children were paralyzed by polio and 125 countries reported polio cases, the World Health Assembly passed a resolution to achieve polio eradication by 2000, and the Global Polio Eradication Initiative (GPEI
Externí odkaz:
https://doaj.org/article/f6d7500491d647e491e3d639b27e3c9d
Publikováno v:
Carbohydrate Research. 118:C5-C6