Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Robert W. Huigens, III"'
Autor:
Jana R. Jenquin, Alana P. O’Brien, Kiril Poukalov, Yidan Lu, Jesus A. Frias, Hannah K. Shorrock, Jared I. Richardson, Hormoz Mazdiyasni, Hongfen Yang, Robert W. Huigens, III, David Boykin, Laura P.W. Ranum, John Douglas Cleary, Eric T. Wang, J. Andrew Berglund
Publikováno v:
iScience, Vol 25, Iss 5, Pp 104198- (2022)
Summary: Myotonic dystrophy type 1 (DM1) and type 2 (DM2) are common forms of adult onset muscular dystrophy. Pathogenesis in both diseases is largely driven by production of toxic-expanded repeat RNAs that sequester MBNL RNA-binding proteins, causin
Externí odkaz:
https://doaj.org/article/58816a4f83314c1bbc07ac1339b064d0
Publikováno v:
SynOpen, Vol 07, Iss 02, Pp 165-185 (2023)
Externí odkaz:
https://doaj.org/article/7ee0a4f96b674cdc8a7355b2c66e0a7f
Autor:
Maria V. Guijarro, Patrick C. Kellish, Peter E. Dib, Nicholas G. Paciaroni, Akbar Nawab, Jacob Andring, Lidia Kulemina, Nicholas V. Borrero, Carlos Modenutti, Michael Feely, Elham Nasri, Robert P. Seifert, Xiaoping Luo, Richard L. Bennett, Daniil Shabashvili, Jonathan D. Licht, Robert McKenna, Adrian Roitberg, Robert W. Huigens III, Frederic J. Kaye, Maria Zajac-Kaye
Publikováno v:
JCI Insight, Vol 8, Iss 10 (2023)
Although thymidylate synthase (TYMS) inhibitors have served as components of chemotherapy regimens, the currently available inhibitors induce TYMS overexpression or alter folate transport/metabolism feedback pathways that tumor cells exploit for drug
Externí odkaz:
https://doaj.org/article/880157298af5466e978ad20aa4f783da
Publikováno v:
SynOpen. :165-185
This graphical review provides a concise overview of indole alkaloids and chemical reactions that have been reported to transform both these natural products and derivatives to rapidly access new molecular scaffolds. Select biologically active compou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5db6d85d178f1e9e00184c5ffca46fe4
https://doi.org/10.1055/a-2048-8412
https://doi.org/10.1055/a-2048-8412
Publikováno v:
ACS infectious diseases. 8(8)
Bacterial biofilms are surface-attached communities of slow- or non-replicating cells embedded within a protective matrix of biomolecules. Unlike free-floating planktonic bacteria, biofilms are innately tolerant to conventional antibiotics and are pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d6d525f20525a13a9a53949a34190b89
https://pubmed.ncbi.nlm.nih.gov/35830188
https://pubmed.ncbi.nlm.nih.gov/35830188
Publikováno v:
MedChemComm. 10(5)
While a number of disinfection techniques are employed in healthcare units, the eradication of drug-resistant microorganisms remains a challenge. We recently reported N-arylated NH125 analogue 1, which demonstrated potent biofilm eradication and anti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::036a96bd8c8db8560b1a580567125f49
https://pubmed.ncbi.nlm.nih.gov/31191861
https://pubmed.ncbi.nlm.nih.gov/31191861
Autor:
Justin J. Richards, Robert W. Huigens III, T. Eric Ballard, Anne Basso, John Cavanagh, Christian Melander
Publikováno v:
Chemical Communications; Mar2008, Vol. 2008 Issue 14, p1698-1700, 3p
Autor:
Garrison AT, Huigens Iii RW; Department of Medicinal Chemistry, Prof. Robert W. Huigens III, University of Florida, Gainesville, USA.
Publikováno v:
Current topics in medicinal chemistry [Curr Top Med Chem] 2016 Dec 14, pp. . Date of Electronic Publication: 2016 Dec 14.