Zobrazeno 1 - 10
of 40
pro vyhledávání: '"Robert W. Coatney"'
Autor:
Santhosh M. Baby, Faisal Zaidi, Gerald E. Hunsberger, David Sokal, Isha Gupta, Silvia V. Conde, Daniel Chew, Kristen Rall, Robert W. Coatney
Publikováno v:
Experimental Physiology, Vol 108, Iss 2, Pp 280-295 (2023)
Abstract The carotid body chemoreceptors (CBC) play an important role in the adaptive counter‐regulatory response to hypoglycaemia by evoking the CBC‐mediated sympathetic neuronal system to restore normoglycaemia. Ex vivo studies have shown varie
Externí odkaz:
https://doaj.org/article/d532d0dd1b3b4818b89b67f0ba51c881
Autor:
David J. Brinkman, Isha Gupta, Paul B. Matteucci, Sebastien Ouchouche, Wouter J. de Jonge, Robert W. Coatney, Tariqus Salam, Daniel J. Chew, Eric Irwin, R. Firat Yazicioglu, Grard A. P. Nieuwenhuizen, Margriet J. Vervoordeldonk, Misha D. P. Luyer
Publikováno v:
Frontiers in Neuroscience, Vol 16 (2022)
IntroductionThe autonomic nervous system is a key regulator of inflammation. Electrical stimulation of the vagus nerve has been shown to have some preclinical efficacy. However, only a few clinical studies have been reported to treat inflammatory dis
Externí odkaz:
https://doaj.org/article/46ffb830c318473e9a85ffb7ff010f4c
Autor:
Santhosh M. Baby, Faisal Zaidi, Gerald E. Hunsberger, David Sokal, Isha Gupta, Silvia V. Conde, Daniel Chew, Kristen Rall, Robert W. Coatney
Publikováno v:
Experimental physiologyREFERENCES.
Funding: Silvia V. Conde declares that Galvani Bioelectronics provided funds to support their work associated with Type 2 diabetic project. New Findings: What is the central question of this study? What are the effects of insulin and insulin-induced
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::194ecb57b46e1da17e1116602a91fcf2
https://pubmed.ncbi.nlm.nih.gov/36459572
https://pubmed.ncbi.nlm.nih.gov/36459572
Autor:
Melissa H Costell, Nicolas eAncellin, Roberta E Bernard, Shufang eZhao, John J Upson, Lisa A Morgan, Kristeen eHauk, Alan R Olzinski, Victoria L T Ballard, Kenny eHerry, Pascal eGrondin, Nerina eDodic, Olivier eMirguet, Anne eBouillot, Francoise eGellibert, Robert W Coatney, John J Lepore, Beat M. Jucker, Larry J Jolivette, Robert N Willette, Christine G Schnackenberg, David J Behm
Publikováno v:
Frontiers in Pharmacology, Vol 3 (2012)
Soluble guanylate cyclase (sGC), the primary mediator of nitric oxide (NO) bioactivity, exists as reduced (NO-sensitive) and oxidized (NO-insensitive) forms. We tested the hypothesis that the cardiovascular protective effects of NO-insensitive sGC ac
Externí odkaz:
https://doaj.org/article/7de0d838ef7f45aba69ae237f3a44947
Publikováno v:
Journal of Pharmacological and Toxicological Methods. 73:15-20
Introduction Advances in echocardiography, including 2-D speckle tracking to quantitate myocardial strain and strain rate, have improved myocardial functional and mechanical evaluation and may provide a more sensitive assessment of cardiac functional
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a4267b7a45427b2fcb5b70e736f2e7ca
https://doi.org/10.1016/j.vascn.2015.02.004
https://doi.org/10.1016/j.vascn.2015.02.004
Publikováno v:
Journal of Pharmaceutical Sciences. 101:2439-2448
To further characterize the time course of gastric pH with respect to meals and gastric residence times (GRTs) in dogs, continuous pH measurements were recorded with Bravo capsules, which were attached to the dogs' stomach mucosa or administered as f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::952b36534f4a7e32d631e6a69275ba58
https://doi.org/10.1002/jps.23159
https://doi.org/10.1002/jps.23159
Autor:
Shufang Zhao, Laura M. Storck, Charles B. Davis, Jeanelle McSurdy-Freed, Robert W. Coatney, Kendall S. Frazier, Catherine X. Hu, Jon Renninger, Tracy L. Gales, Kevin French, Emile Chen
Publikováno v:
Toxicologic Pathology. 38:691-702
Several multikinase angiogenesis inhibitors demonstrate mitochondrial and/or cardiovascular toxicity, suggesting an on-target pharmacologic effect. To evaluate whether cardiotoxicity is directly related to vascular endothelial growth factor receptor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff8d4a5772d8c94ac8da7b11bb9b9753
https://doi.org/10.1177/0192623310373775
https://doi.org/10.1177/0192623310373775
Autor:
Timothy D. Westfall, Chris P. Doe, Shufang Zhao, Ross G. Bentley, Alan R. Olzinski, Robert W. Coatney, Marianne E. Eybye, Kristeen Maniscalco, Robert N. Willette, Nambi Aiyar, David J. Behm
Publikováno v:
Journal of Pharmacology and Experimental Therapeutics. 330:964-970
The evidence is compelling for a role of inflammation in cardiovascular diseases; however, the chronic use of anti-inflammatory drugs for these indications has been disappointing. The recent study compares the effects of two anti-inflammatory agents
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad4afb6033e6cd0e7c28aaf30d94e8b7
https://doi.org/10.1124/jpet.109.154443
https://doi.org/10.1124/jpet.109.154443
Publikováno v:
Journal of Urology. 181:1444-1451
Urodynamics have been traditionally recorded in anesthetized or conscious animals implanted with a bladder catheter that is used to artificially fill the bladder while measuring intravesicular bladder pressure. Anesthesia alters the urodynamics and i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a39991239d761ee16a0cd9952158a809
https://doi.org/10.1016/j.juro.2008.10.137
https://doi.org/10.1016/j.juro.2008.10.137
Autor:
Erin S. Riedel, Christopher P. Evans, Gerald P. McCafferty, Gian C Rivera, Nambi Aiyar, Robert W. Coatney, Trudy D Luce, Timothy D. Westfall, Mark Pullen, J. Paul Hieble, Alexandra Hicks
Publikováno v:
Journal of Pharmacology and Experimental Therapeutics. 323:202-209
Functional studies have demonstrated that adrenoceptor agonist-evoked relaxation is mediated primarily by beta3-adrenergic receptors (ARs) in human bladder. Thus, the use of selective beta3-AR agonists in the pharmacological treatment of overactive b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d17cdfb1ca21c612e6d9888dac476f51
https://doi.org/10.1124/jpet.107.125757
https://doi.org/10.1124/jpet.107.125757