Zobrazeno 1 - 10
of 45
pro vyhledávání: '"Robert W. Brock"'
Autor:
Brayden D. Halvorson, Nithin J. Menon, Daniel Goldman, Stephanie J. Frisbee, Adam G. Goodwill, Joshua T. Butcher, Phoebe A. Stapleton, Steven D. Brooks, Alexandre C. d’Audiffret, Robert W. Wiseman, Julian H. Lombard, Robert W. Brock, I. Mark Olfert, Paul D. Chantler, Jefferson C. Frisbee
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 323:H475-H489
The study of peripheral vasculopathy with chronic metabolic disease is challenged by divergent contributions from spatial (the level of resolution or specific tissue being studied) and temporal origins (evolution of the developing impairments in time
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::abf289216649d0ddc8dbcc88b3deed2f
https://doi.org/10.1152/ajpheart.00264.2022
https://doi.org/10.1152/ajpheart.00264.2022
Autor:
Martin Alexander Schick, Christian Wunder, Robert W Brock, Reinhard Schneider, Jakob Wollborn, Nicolas Schlegel, Sven Flemming, Wolfgang Baar, Natalie Burkard
Publikováno v:
Journal of visualized experiments : JoVE. (180)
AKI in septic patients is associated with increased mortality and poor outcome despite major efforts to refine the understanding of its pathophysiology. Here, an in vivo model is presented that combines a standardized septic focus to induce AKI and a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ecfd25c7543eaf1add38b487446db29a
https://pubmed.ncbi.nlm.nih.gov/35253793
https://pubmed.ncbi.nlm.nih.gov/35253793
Autor:
Robert W. Brock, Paul Ndebele, Lehana Thabane, Nancy L. Jones, Kathleen H. Moore, Marion G. Ben-Jacob
Publikováno v:
International Journal of Ethics Education. 3:125-133
Scientific endeavor is the pursuit of knowledge with the aim of advancing the welfare of all human beings. This endeavor is built on the ideology of science; thus, society relies on the integrity of the practice of science and of scientists themselve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::587d6cd7c5a960facd0d6e54dccecb97
https://doi.org/10.1007/s40889-018-0060-8
https://doi.org/10.1007/s40889-018-0060-8
Autor:
Zahra Farid, Carl D. Shrader, Daniel Goldman, Kent A. Lemaster, Robert W. Brock, Dwayne N. Jackson, Jefferson C. Frisbee
Publikováno v:
The Journal of Physiology. 595:5159-5174
Key points With the development of the metabolic syndrome, both post-capillary and collecting venular dilator reactivity within the skeletal muscle of obese Zucker rats (OZR) is impaired. The impaired dilator reactivity in OZR reflects a loss in venu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1440f963e3549d99cf295b55a801dea6
https://doi.org/10.1113/jp274291
https://doi.org/10.1113/jp274291
Autor:
Paul D. Chantler, Stephanie J. Frisbee, I. Mark Olfert, Carl D. Shrader, Jefferson C. Frisbee, Lawrence E. Tabone, Phoebe A. Stapleton, Julian H. Lombard, Steven D. Brooks, Robert W. Brock, Joshua T. Butcher, Adam G. Goodwill, Alexandre d'Audiffret
To determine the impact of progressive elevations in peripheral vascular disease (PVD) risk on microvascular function, we utilized eight rat models spanning “healthy” to “high PVD risk” and used a multiscale approach to interrogate microvascu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d7d1763fdd9632dee0e420d990c8967b
https://europepmc.org/articles/PMC4796615/
https://europepmc.org/articles/PMC4796615/
Publikováno v:
American Journal of Physiology-Regulatory, Integrative and Comparative Physiology. 296:R1771-R1782
Previous study suggests that with evolution of the metabolic syndrome, patterns of arteriolar reactivity are profoundly altered and may constrain functional hyperemia. This study investigated interactions between parameters of vascular reactivity at
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d90890d1607ea907a94fe506d69b5800
https://doi.org/10.1152/ajpregu.00096.2009
https://doi.org/10.1152/ajpregu.00096.2009
Autor:
Robert B. Dorman, Robert W. Brock
Publikováno v:
Microcirculation. 14:339-347
Insulin resistance brings together the collection of hyperglycemia, hyperinsulinemia, and dyslipidemia associated with pathologies such as obesity and type 2 diabetes. As such, it is an important target for the prevention of complications linked with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dfe59227895911ad382884b2ba829d44
https://doi.org/10.1080/10739680701282986
https://doi.org/10.1080/10739680701282986
Autor:
Philip R. Mayeux, Kurt J. Messer, Robert W. Brock, Joseph H. Holthoff, Neriman Gokden, Liping Wu, Manish M. Tiwari
Publikováno v:
American Journal of Physiology-Renal Physiology. 292:F261-F268
The mortality rate for septic patients with acute renal failure is extremely high. Since sepsis is often caused by lipopolysaccharide (LPS), a model of LPS challenge was used to study the development of kidney injury. Intravital video microscopy was
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f01b55b2cda16b3e65b91e6709e8e96a
https://doi.org/10.1152/ajprenal.00263.2006
https://doi.org/10.1152/ajprenal.00263.2006
Publikováno v:
The FASEB Journal. 29
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7079a4e87700de0ce434f54e59765793
https://doi.org/10.1096/fasebj.29.1_supplement.664.5
https://doi.org/10.1096/fasebj.29.1_supplement.664.5
Publikováno v:
American Journal of Physiology-Renal Physiology. 289:F1324-F1332
Acute renal failure (ARF) is a frequent and serious complication of endotoxemia caused by lipopolysaccharide (LPS) and contributes significantly to mortality. The present studies were undertaken to examine the roles of nitric oxide (NO) and caspase a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d8a6210e30ca51362e12a8ca40a65a3
https://doi.org/10.1152/ajprenal.00124.2005
https://doi.org/10.1152/ajprenal.00124.2005