Pragmatic randomised clinical trial of proton versus photon therapy for patients with non-metastatic breast cancer: the Radiotherapy Comparative Effectiveness (RadComp) Consortium trial protocol

Autor: Bonnie Ky, Justin E Bekelman, Hien Lu, Stephanie Pugh, Kaysee Baker, Christine D Berg, Amy Berrington de Gonzalez, Lior Z Braunstein, Walter Bosch, Cynthia Chauhan, Susan Ellenberg, L Christine Fang, Gary M Freedman, Elizabeth A Hahn, B G Haffty, Atif J Khan, Rachel B Jimenez, Christy Kesslering, Choonsik Lee, Hsiao-Ming Lu, Mark V Mishra, C Daniel Mullins, Robert W Mutter, Suneel Nagda, Mark Pankuch, Simon N Powell, Fred W Prior, Karen Schupak, Alphonse G Taghian, J Ben Wilkinson, Shannon M MacDonald, Oren Cahlon, David Gierga, Harald Paganetti, Daniel Soto, Aman Anand, Michele Halyard, Lisa A. McGee, Kimberly Corbin, Nicholas Remmes, Elizabeth Yan, Elizabeth S. Bloom, Karen E. Hoffman, Falk Poenisch, Benjamin Smith, Xiaorong Ronald Zhu, John Cuaron, Daphna Gelblum, Erin Gillespie, Linda Hong, Beryl McCormick, Borys Mychalczak, Preeti Parhar, Paul Romesser, Anne Marie Shepherd, Jaffa Bennouna, Marcio Fagundes, Alonso Gutierrez, Jennifer Yu, David Cella, Stephen Mihalcik, Michael Stutz, Tomas Dvorak, Omar Zeidan, Eugene Fourkal, David C. Weksberg, Dennis Mah, Henry Tsai, Jeffrey Campbell, Kiran Prabhu, Trevor Twyford, Allen Meek, Niek Schreuder, Sharad Goyal, Rihan Millevoi, Nisha Ohri, Chang Chang, Jared Sturgeon, William Bennet, Lawrence Tarbox, Jyoti Mayadev, Vitali Moiseenko, Dominique Rash, James Urbanic, Catheryn Yashar, Julie A. Bradley, Xiaoying Liang, Nancy Mendenhall, Michael Rutenberg, Chee-Wai Cheng, Janice Lyons, Katja Langen, Elizabeth Nichols, Abigail Berman, Steven Feigenberg, James Volker, Lilie Lin, Ann Marie Siegal, Neil Taunk, Tony Wong, Sasa Music, William Straube, Imran Zoberi, Peter Chen, Xuanfeng Ding, Phuong Daniella Dang, Sanford Katz, Lane R Rosen, Terry Wu

Publikováno v: BMJ Open, Vol 9, Iss 10 (2019)

Introduction A broad range of stakeholders have called for randomised evidence on the potential clinical benefits and harms of proton therapy, a type of radiation therapy, for patients with breast cancer. Radiation therapy is an important component o

Externí odkaz: https://doaj.org/article/9cffbe14e2d44b8eb8a4a5d432726a53

Long-term outcomes of intraoperatively-placed applicator brachytherapy for rapid completion of breast conserving treatment: An analysis of a prospective registry data

Autor: Haeyoung Kim, Tina J. Hieken, Feven Abraha, James W. Jakub, Kimberly S. Corbin, Keith M. Furutani, Judy C. Boughey, Bradley J. Stish, Christopher L. Deufel, Amy C. Degnim, Dean A. Shumway, Safia K. Ahmed, Mara A. Piltin, Nicole P. Sandhu, Amy L. Conners, Kathryn J. Ruddy, Robert W. Mutter, Sean S. Park

Publikováno v: Clinical and Translational Radiation Oncology, Vol 41, Iss , Pp 100639- (2023)

Background and purpose: To evaluate the long-term outcome of accelerated partial breast irradiation utilizing intraoperatively placed applicator-based brachytherapy (ABB) in early-stage breast cancer. Materials and methods: From our prospective regis

Externí odkaz: https://doaj.org/article/0f34b72eae2b49d190cb40579d87c058

Intensity Modulated Proton Therapy for Bilateral Breast or Chest Wall and Comprehensive Nodal Irradiation for Synchronous Bilateral Breast Cancer: Initial Clinical Experience and Dosimetric Comparison

Autor: Allison E. Garda, MD, Ashley E. Hunzeker, CMD, Ann K. Michel, RT(T), CMD, Sayeh Fattahi, BS, Satomi Shiraishi, PhD, Nicholas B. Remmes, PhD, Heather L. Schultz, RT(T), CMD, W. Scott Harmsen, MS, Dean A. Shumway, MD, Elizabeth S. Yan, MD, Sean S. Park, MD, PhD, Robert W. Mutter, MD, Kimberly S. Corbin, MD

Publikováno v: Advances in Radiation Oncology, Vol 7, Iss 3, Pp 100901- (2022)

Purpose: Synchronous bilateral breast cancer (SBBC) poses distinct challenges for radiation therapy planning. We report our proton therapy experience in treating patients with SBBC. We also provide a dosimetric comparison of intensity modulated proto

Externí odkaz: https://doaj.org/article/f5764ea206cf44b492dc71431a8f21e8

Author Correction: The bromodomain containing protein BRD-9 orchestrates RAD51–RAD54 complex formation and regulates homologous recombination-mediated repair

Autor: Qin Zhou, Jinzhou Huang, Chao Zhang, Fei Zhao, Wootae Kim, Xinyi Tu, Yong Zhang, Somaira Nowsheen, Qian Zhu, Min Deng, Yuping Chen, Bo Qin, Kuntian Luo, Baohua Liu, Zhenkun Lou, Robert W. Mutter, Jian Yuan

Publikováno v: Nature Communications, Vol 13, Iss 1, Pp 1-1 (2022)

Externí odkaz: https://doaj.org/article/205fe899bc10419db419cb385b54a7d3

Reirradiation for Locoregional Recurrent Breast Cancer

Autor: Sayeh Fattahi, BS, Safia K. Ahmed, MD, Sean S. Park, MD, PhD, Ivy A. Petersen, MD, Dean A. Shumway, MD, Bradley J. Stish, MD, Elizabeth S. Yan, MD, Nicholas B. Remmes, PhD, Robert W. Mutter, MD, Kimberly S. Corbin, MD

Publikováno v: Advances in Radiation Oncology, Vol 6, Iss 1, Pp 100640- (2021)

Purpose: Reirradiation poses a distinct therapeutic challenge owing to risks associated with exceeding normal tissue tolerances and possibly more therapeutically resistant disease biology. We report our experience with reirradiation for locoregional

Externí odkaz: https://doaj.org/article/f14adaacdb8445d7847830d651706b22