Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Robert W E Crozier"'
Publikováno v:
Journal of Leukocyte Biology.
Mast cells are leukocytes that mediate various aspects of immunity and drive allergic hypersensitivity pathologies. Mast cells differentiate from hematopoietic progenitor cells in a manner that is largely IL-3 dependent. However, molecular mechanisms
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cda09ec44f0de24f83b219026a411981
https://doi.org/10.1093/jleuko/qiad050
https://doi.org/10.1093/jleuko/qiad050
Publikováno v:
The FASEB Journal. 37
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::69f183fbee67a7a6a026c219ef60cd5b
https://doi.org/10.1096/fj.202201272r
https://doi.org/10.1096/fj.202201272r
Publikováno v:
European journal of immunology.
Mast cells are granulated immune sentinels responsible for allergic inflammation. Allergen-induced FcεRI-signaling leads to rapid degranulation in the early-phase and sustained production and release of pro-inflammatory mediators in the late-phase.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::63d419bfc01f3b42f9480b0cfb99d076
https://pubmed.ncbi.nlm.nih.gov/36349527
https://pubmed.ncbi.nlm.nih.gov/36349527
Autor:
Jeremia M. Coish, Robert W. E. Crozier, John S. Schieffelin, Jens R. Coorssen, Fiona F. Hunter, Adam J. MacNeil
Publikováno v:
Microbiology spectrum. 10(4)
Antibodies generated against one dengue serotype can enhance infection of another by a phenomenon called antibody-dependent enhancement (ADE). Additionally, antigenic similarities between Zika and dengue viruses can promote Zika virus infection by wa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0382fd10308d5d923197e7f4fd2bb854
https://pubmed.ncbi.nlm.nih.gov/35862953
https://pubmed.ncbi.nlm.nih.gov/35862953
Autor:
Val A. Fajardo, Robert W. E. Crozier, Michael Yousef, Adam J. MacNeil, Colton J. F. Watson, Kelly Bruton, Melissa M. Rouillard, Aindriu R. R. Maguire
Publikováno v:
Journal of Leukocyte Biology. 107:649-661
Mast cells drive the inappropriate immune response characteristic of allergic inflammatory disorders via release of pro-inflammatory mediators in response to environmental cues detected by the IgE-FcεRI complex. The role of TGF-β-activated kinase 1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::913fe807fa8c999b256a19d3d559eb92
https://doi.org/10.1002/jlb.2a0220-401rrr
https://doi.org/10.1002/jlb.2a0220-401rrr
Autor:
Katie D Hunter, Adam J. MacNeil, Robert W. E. Crozier, Val A. Fajardo, Paul J. LeBlanc, Steven M. Claypool, Aindriu R. R. Maguire
Publikováno v:
ImmunoHorizons. 5(4)
Allergic inflammatory diseases are a steadily growing health concern. Mast cells, a driving force behind allergic pathologies, modulate metabolic pathways to carry out various functions following IgE-FcεRI–mediated activation. Tafazzin (TAZ) is a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2dcd131de39c029916985f79ce7b708b
https://pubmed.ncbi.nlm.nih.gov/33895725
https://pubmed.ncbi.nlm.nih.gov/33895725
Autor:
Robert W. E. Crozier, Tylar Boyd, Evangelia Tsiani, Michael Yousef, Adam J. MacNeil, Natalie J. Hicks, Colton J. F. Watson
Publikováno v:
Journal of leukocyte biologyREFERENCES. 107(5)
Mast cells are immune sentinels and a driving force in both normal and pathological contexts of inflammation, with a prominent role in allergic hypersensitivities. Crosslinking of FcεRI by allergen-bound IgE Abs leads to mast cell degranulation, res
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db40d045ce1decfa60626f3d6ad55652
https://pubmed.ncbi.nlm.nih.gov/32202360
https://pubmed.ncbi.nlm.nih.gov/32202360
Autor:
Jeremia M Coish, Robert W. E. Crozier, John S. Schieffelin, Jens R. Coorssen, Fiona F. Hunter, Adam J. MacNeil
Publikováno v:
The Journal of Immunology. 204:248.13-248.13
Dengue virus (DENV) infection is augmented by a process called antibody-dependent enhancement (ADE), in which pre-existing DENV immunity can render an individual more susceptible to a subsequent DENV exposure. Based on Zika virus (ZIKV) and DENV stru
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5a3535c992f486e68b30192e469fe508
https://doi.org/10.4049/jimmunol.204.supp.248.13
https://doi.org/10.4049/jimmunol.204.supp.248.13
Autor:
Colton J. F. Watson, Melissa M. Rouillard, Robert W. E. Crozier, Val A. Fajardo, Adam J. MacNeil
Publikováno v:
The Journal of Immunology. 204:66.1-66.1
Allergic inflammation is an inappropriate immune response, typically triggered by activated mast cells that have been IgE-sensitized to innocuous environmental agents. Allergic inflammatory events can be split into two phases, early and late, initiat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::126b033095437cde68c4ac1f6ad71836
https://doi.org/10.4049/jimmunol.204.supp.66.1
https://doi.org/10.4049/jimmunol.204.supp.66.1
Autor:
Robert W. E. Crozier, Danja J. Den Hartogh, Adam J. MacNeil, Lori A. MacNeil, Natalie J. Hicks
Publikováno v:
The FASEB Journal. 34:1-1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9e5a6b6369112011907f0e4949b4dbc0
https://doi.org/10.1096/fasebj.2020.34.s1.04523
https://doi.org/10.1096/fasebj.2020.34.s1.04523