Zobrazeno 1 - 10
of 131
pro vyhledávání: '"Robert W Cross"'
Autor:
Robert W Cross, Ira M Longini, Stephan Becker, Karin Bok, David Boucher, Miles W Carroll, Janet V Díaz, William E Dowling, Ruxandra Draghia-Akli, James T Duworko, John M Dye, Michael A Egan, Patricia Fast, Amy Finan, Courtney Finch, Thomas R Fleming, Joan Fusco, Thomas W Geisbert, Anthony Griffiths, Stephan Günther, Lisa E Hensley, Anna Honko, Ruth Hunegnaw, Jocelyn Jakubik, Julie Ledgerwood, Kerstin Luhn, Demetrius Matassov, Jeffrey Meshulam, Emily V Nelson, Christopher L Parks, Roxana Rustomjee, David Safronetz, Lauren M Schwartz, Dean Smith, Paul Smock, Ydrissa Sow, Christina F Spiropoulou, Nancy J Sullivan, Kelly L Warfield, Daniel Wolfe, Courtney Woolsey, Roland Zahn, Ana María Henao-Restrepo, César Muñoz-Fontela, Andrea Marzi
Publikováno v:
PLoS Pathogens, Vol 18, Iss 10, p e1010805 (2022)
The emergence of Marburg virus (MARV) in Guinea and Ghana triggered the assembly of the MARV vaccine "MARVAC" consortium representing leaders in the field of vaccine research and development aiming to facilitate a rapid response to this infectious di
Externí odkaz:
https://doaj.org/article/593ffe829fc54b1d9a21138ad004f3f4
Autor:
Courtney Woolsey, Robert W Cross, Krystle N Agans, Viktoriya Borisevich, Daniel J Deer, Joan B Geisbert, Cheryl Gerardi, Theresa E Latham, Karla A Fenton, Michael A Egan, John H Eldridge, Thomas W Geisbert, Demetrius Matassov
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 16, Iss 5, p e0010433 (2022)
BackgroundMarburg virus (MARV), an Ebola-like virus, remains an eminent threat to public health as demonstrated by its high associated mortality rate (23-90%) and recent emergence in West Africa for the first time. Although a recombinant vesicular st
Externí odkaz:
https://doaj.org/article/03f5f518f8bc426ba64de4f125e7cfd9
Autor:
Robert W Cross, Abhishek N Prasad, Viktoriya Borisevich, Joan B Geisbert, Krystle N Agans, Daniel J Deer, Karla A Fenton, Thomas W Geisbert
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 14, Iss 8, p e0008637 (2020)
BackgroundDevelopment of vaccines and therapies against Crimean-Congo hemorrhagic fever virus (CCHFV) have been hindered by the lack of immunocompetent animal models. Recently, a lethal nonhuman primate model based on the CCHFV Hoti strain was report
Externí odkaz:
https://doaj.org/article/ff901c05cee941cb88ff3c3088fb873d
Autor:
Courtney Woolsey, Robert W. Cross, Abhishek N. Prasad, Krystle N. Agans, Viktoriya Borisevich, Daniel J. Deer, Natalie S. Dobias, Alyssa C. Fears, Mack B. Harrison, Megan L. Heinrich, Karla A. Fenton, Robert F. Garry, Luis M. Branco, Thomas W. Geisbert
Publikováno v:
Emerging Microbes and Infections, Vol 13, Iss 1 (2024)
ABSTRACTLassa virus (LASV) is a World Health Organization (WHO) priority pathogen that causes high morbidity and mortality. Recently, we showed that a combination of three broadly neutralizing human monoclonal antibodies known as Arevirumab-3 (8.9F,
Externí odkaz:
https://doaj.org/article/055f26a5860147ff8cc66a9db9b3c6b4
Autor:
Jeffrey G Shaffer, Donald S Grant, John S Schieffelin, Matt L Boisen, Augustine Goba, Jessica N Hartnett, Danielle C Levy, Rachael E Yenni, Lina M Moses, Mohammed Fullah, Mambo Momoh, Mbalu Fonnie, Richard Fonnie, Lansana Kanneh, Veronica J Koroma, Kandeh Kargbo, Darin Ottomassathien, Ivana J Muncy, Abigail B Jones, Megan M Illick, Peter C Kulakosky, Allyson M Haislip, Christopher M Bishop, Deborah H Elliot, Bethany L Brown, Hu Zhu, Kathryn M Hastie, Kristian G Andersen, Stephen K Gire, Shervin Tabrizi, Ridhi Tariyal, Mathew Stremlau, Alex Matschiner, Darryl B Sampey, Jennifer S Spence, Robert W Cross, Joan B Geisbert, Onikepe A Folarin, Christian T Happi, Kelly R Pitts, F Jon Geske, Thomas W Geisbert, Erica Ollmann Saphire, James E Robinson, Russell B Wilson, Pardis C Sabeti, Lee A Henderson, S Humarr Khan, Daniel G Bausch, Luis M Branco, Robert F Garry, Viral Hemorrhagic Fever Consortium
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 8, Iss 3, p e2748 (2014)
BACKGROUND:Lassa fever (LF), an often-fatal hemorrhagic disease caused by Lassa virus (LASV), is a major public health threat in West Africa. When the violent civil conflict in Sierra Leone (1991 to 2002) ended, an international consortium assisted i
Externí odkaz:
https://doaj.org/article/55ad3c3b355949c08ef8d3693670c434
Autor:
Robert W. Cross, Abhishek N. Prasad, Courtney B. Woolsey, Krystle N. Agans, Viktoriya Borisevich, Natalie S. Dobias, Jason E. Comer, Daniel J. Deer, Joan B. Geisbert, Angela L. Rasmussen, Walter Ian Lipkin, Karla A. Fenton, Thomas W. Geisbert
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-12 (2023)
Abstract Transmission of Ebola virus (EBOV) primarily occurs via contact exposure of mucosal surfaces with infected body fluids. Historically, nonhuman primate (NHP) challenge studies have employed intramuscular (i.m.) or small particle aerosol expos
Externí odkaz:
https://doaj.org/article/e50fc8bae44c4bac9ac933f1779af9f9
Autor:
Robert W. Cross, Christopher M. Wiethoff, Patricia Brown-Augsburger, Shawn Berens, Jamie Blackbourne, Ling Liu, Xiaohua Wu, Jonathan Tetreault, Carter Dodd, Ramtin Sina, Derrick R. Witcher, Deanna Newcomb, Denzil Frost, Angela Wilcox, Viktoriya Borisevich, Krystle N. Agans, Courtney Woolsey, Abhishek N. Prasad, Daniel J. Deer, Joan B. Geisbert, Natalie S. Dobias, Karla A. Fenton, Beth Strifler, Philip Ebert, Richard Higgs, Anne Beall, Sumit Chanda, Laura Riva, Xin Yin, Thomas W. Geisbert
Publikováno v:
Pathogens, Vol 12, Iss 12, p 1408 (2023)
As part of the non-clinical safety package characterizing bamlanivimab (SARS-CoV-2 neutralizing monoclonal antibody), the risk profile for antibody-dependent enhancement of infection (ADE) was evaluated in vitro and in an African green monkey (AGM) m
Externí odkaz:
https://doaj.org/article/f7f4761387234185a8923bd4c6b15ef6
Autor:
Courtney Woolsey, Viktoriya Borisevich, Alyssa C. Fears, Krystle N. Agans, Daniel J. Deer, Abhishek N. Prasad, Rachel O’Toole, Stephanie L. Foster, Natalie S. Dobias, Joan B. Geisbert, Karla A. Fenton, Robert W. Cross, Thomas W. Geisbert
Publikováno v:
The Journal of Clinical Investigation, Vol 133, Iss 3 (2023)
The emergence of the novel henipavirus, Langya virus, received global attention after the virus sickened over three dozen people in China. There is heightened concern that henipaviruses, as respiratory pathogens, could spark another pandemic, most no
Externí odkaz:
https://doaj.org/article/6fae00c584d04cfdac053badea1f2c59
Autor:
Moushimi Amaya, Randy Yin, Lianying Yan, Viktoriya Borisevich, Bishwo N. Adhikari, Andrew Bennett, Francisco Malagon, Regina Z. Cer, Kimberly A. Bishop-Lilly, Antony S. Dimitrov, Robert W. Cross, Thomas W. Geisbert, Christopher C. Broder
Publikováno v:
Viruses, Vol 15, Iss 5, p 1077 (2023)
The henipaviruses, Nipah virus (NiV), and Hendra virus (HeV) can cause fatal diseases in humans and animals, whereas Cedar virus is a nonpathogenic henipavirus. Here, using a recombinant Cedar virus (rCedV) reverse genetics platform, the fusion (F) a
Externí odkaz:
https://doaj.org/article/335eab983bc343c08d5dd66d42df9af6
Autor:
Xin Ye, Richard Holland, Mark Wood, Chris Pasetka, Lorne Palmer, Eleni Samaridou, Kevin McClintock, Viktoriya Borisevich, Thomas W. Geisbert, Robert W. Cross, James Heyes
Publikováno v:
Molecular Therapy. 31:269-281
Marburg virus (MARV) infection results in severe viral hemorrhagic fever with mortalities up to 90%, and there is a pressing need for effective therapies. Here, we established a small interfering RNA (siRNA) conjugate platform that enabled successful