Výsledky vyhledávání - "Robert Vinkler"

Comparison of multiparametric MRI ‐based and transrectal ultrasound‐based preplans with intraoperative ultrasound‐based planning for low dose rate interstitial prostate seed implantation

Autor: Rodney J. Ellis, Robert Vinkler, Elisha T. Fredman, Andrew Gross, Bryan Traughber, Mitchell Machtay, Tarun Podder, Valdir C. Colussi

Publikováno v: Journal of Applied Clinical Medical Physics

Purpose Transrectal ultrasound images are routinely acquired for low dose rate (LDR) prostate brachytherapy dosimetric preplanning (pTRUS), although diagnostic multiparametric magnetic resonance imaging (mpMRI) may serve this purpose as well. We comp

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f32b2cad23a9ab378206da3bf80d2c7b
https://doi.org/10.1002/acm2.12592

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MCT4 regulates de novo pyrimidine biosynthesis in GBM in a lactate-independent manner

Autor: Norbert Avril, Eli E. Bar, Robert Vinkler, Anthony Sloan, Jason W. Sohn, Scott M. Welford, Dillon M. Voss, Julianna Schraner, Heather M. Ames, Graeme F. Woodworth, Xiaohua Yang, Raffaella Spina

Publikováno v: Neuro-Oncology Advances

Background Necrotic foci with surrounding hypoxic cellular pseudopalisades and microvascular hyperplasia are histological features found in glioblastoma (GBM). We have previously shown that monocarboxylate transporter 4 (MCT4) is highly expressed in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc3ff5f6aec65f7ba98b3c0df271a0f4
https://doi.org/10.1093/noajnl/vdz062

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The Ig superfamily protein PTGFRN coordinates survival signaling in Glioblastoma multiforme

Autor: Robert Vinkler, Brittany Aguila, Scott M. Welford, Julie Schraner, Adina Brett Morris, Eli E. Bar, Raffaella Spina, Jason W. Sohn

Publikováno v: Cancer Lett

Glioblastoma multiforme (GBM) is the most malignant primary brain tumor with a median survival of approximately 14 months. Despite aggressive treatment of surgical resection, chemotherapy and radiation therapy, only 3-5% of GBM patients survive more

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b066597c473404afd4ea19a29c282a65
https://europepmc.org/articles/PMC6705426/

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STEM-19. MONOCARBOXYLATE TRANSPORTER-4 DEPLETION INHIBITS STEMNESS, PROMOTES DNA DAMAGE AND RADIOSENSITIZES GLIOBLASTOMA STEM CELLS

Autor: Eli E. Bar, Anthony Sloan, Jason W. Sohn, Scott M. Welford, Dillon M. Voss, Julianna Schraner, Raffaella Spina, Robert Vinkler

Glioblastoma multiforme (GBM) is the most aggressive brain tumor in adults, with a median survival for patients of 12–15 months after diagnosis. Standard therapy includes radiation and chemotherapy, with GBM recurrences refractory to second line tr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba435f3d5dfc5f58b72202b9ed9e7e5a
https://europepmc.org/articles/PMC6216210/

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Phase II Trial of Radiosurgery to Magnetic Resonance Spectroscopy–Defined High-Risk Tumor Volumes in Patients With Glioblastoma Multiforme

Autor: Jonathan S. Lewin, Douglas B. Einstein, Barbara A. Bangert, Valdir C. Colussi, Stephen M. Sagar, Jordonna Williams, Robert Vinkler, Pingfu Fu, Mark L. Cohen, A. Dennis Nelson, Barry W. Wessels, Y. Zheng, Robert J. Maciunas, Andrew E. Sloan

Publikováno v: International Journal of Radiation Oncology*Biology*Physics. 84:668-674

Purpose To determine the efficacy of a Gamma Knife stereotactic radiosurgery (SRS) boost to areas of high risk determined by magnetic resonance spectroscopy (MRS) functional imaging in addition to standard radiotherapy for patients with glioblastoma

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::50edfec0f7a72348366c74339c3137af
https://doi.org/10.1016/j.ijrobp.2012.01.020

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Interstitial Prostate Brachytherapy Outcomes (1992-2002): Late Urinary Function Following Molecular Image-Guided Therapy

Autor: Rodney J. Ellis, Shree Agrawal, Mitchell Machtay, Valdir C. Colussi, Robert Abouassaly, Bryan Traughber, Lee Ponsky, Deborah A. Kaminsky, Robert Vinkler, Tarun Podder, April Deters

Publikováno v: Brachytherapy. 13:S119

treatments using BED 5 nd [1þ (d/a/b)] and for low-dose-rate I125 or Pd103 BED 5 (R0/l) {1þ[R0 ⁄(mþl)(a/b)]} a/b of 1.86 and 3 Gy were applied for prostate cancer and normal tissue respectively. The BED values for treatments involving both impla

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::d90adadb2c8431e87b21738928e1bc95
https://doi.org/10.1016/j.brachy.2014.02.425

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