Zobrazeno 1 - 10
of 60
pro vyhledávání: '"Robert Vendramelli"'
Autor:
Amrit S. Boese, Bryce M. Warner, Peter McQueen, Robert Vendramelli, Nikesh Tailor, Bryan D. Griffin, Mable Chan, Jonathan Audet, Anders Leung, Stuart McCorrister, Chris Grant, Garrett Westmacott, Darwyn Kobasa
Publikováno v:
npj Viruses, Vol 2, Iss 1, Pp 1-11 (2024)
Abstract Long COVID or post-acute sequelae of COVID-19 (PASC) remains an ongoing public health issue that causes impairment for those afflicted and diminishes their ability to contribute to society. To address the host response underpinning respirato
Externí odkaz:
https://doaj.org/article/e9b2d7eed93843c38410c3049f38af04
Autor:
Bryce M. Warner, Jacob G. E. Yates, Robert Vendramelli, Thang Truong, Courtney Meilleur, Lily Chan, Alexander Leacy, Phuc H. Pham, Yanlong Pei, Leonardo Susta, Sarah K. Wootton, Darwyn Kobasa
Publikováno v:
npj Vaccines, Vol 9, Iss 1, Pp 1-16 (2024)
Abstract The rapid development and deployment of vaccines following the emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has been estimated to have saved millions of lives. Despite their immense success, there remains a need
Externí odkaz:
https://doaj.org/article/b78b1299d4d84b4391ebcbff29360bfd
Autor:
Bryce M. Warner, Mable Chan, Nikesh Tailor, Robert Vendramelli, Jonathan Audet, Courtney Meilleur, Thang Truong, Lauren Garnett, Marnie Willman, Geoff Soule, Kevin Tierney, Alixandra Albietz, Estella Moffat, Rick Higgins, Lisa A. Santry, Alexander Leacy, Phuc H. Pham, Jacob G. E. Yates, Yanlong Pei, David Safronetz, James E. Strong, Leonardo Susta, Carissa Embury-Hyatt, Sarah K. Wootton, Darwyn Kobasa
Publikováno v:
Vaccines, Vol 12, Iss 4, p 404 (2024)
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) emerged following an outbreak of unexplained viral illness in China in late 2019. Since then, it has spread globally causing a pandemic that has resulted in millions of deaths and has had e
Externí odkaz:
https://doaj.org/article/5e4cccc3f31e4e15bd81f344156fe762
Autor:
Kyle LeBlanc, Jessie Lynch, Christine Layne, Robert Vendramelli, Angela Sloan, Nikesh Tailor, Yvon Deschambault, Fushun Zhang, Darwyn Kobasa, David Safronetz, Yan Xiang, Jingxin Cao
Publikováno v:
Microbiology Spectrum, Vol 11, Iss 3 (2023)
ABSTRACT Coronaviruses (CoVs), including severe acute respiratory syndrome CoV (SARS-CoV), Middle East respiratory syndrome CoV (MERS-CoV), and SARS-CoV-2, produce double-stranded RNA (dsRNA) that activates antiviral pathways such as PKR and OAS/RNas
Externí odkaz:
https://doaj.org/article/73fcb0d71715445dbe5f0a8ebe2b1962
Autor:
Bryan D. Griffin, Mable Chan, Nikesh Tailor, Emelissa J. Mendoza, Anders Leung, Bryce M. Warner, Ana T. Duggan, Estella Moffat, Shihua He, Lauren Garnett, Kaylie N. Tran, Logan Banadyga, Alixandra Albietz, Kevin Tierney, Jonathan Audet, Alexander Bello, Robert Vendramelli, Amrit S. Boese, Lisa Fernando, L. Robbin Lindsay, Claire M. Jardine, Heidi Wood, Guillaume Poliquin, James E. Strong, Michael Drebot, David Safronetz, Carissa Embury-Hyatt, Darwyn Kobasa
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-10 (2021)
Deer mice are natural hosts for a number of human pathogens. Here, Griffin et al. report that intranasal exposure of the North American deer mouse to SARS-CoV-2 results in virus replication and shedding, despite causing only mild or asymptomatic illn
Externí odkaz:
https://doaj.org/article/9da1c4d9e45e4f76a8779fa6d68d2b3b
Autor:
Bryan D. Griffin, Bryce M. Warner, Mable Chan, Emelissa Valcourt, Nikesh Tailor, Logan Banadyga, Anders Leung, Shihua He, Amrit S. Boese, Jonathan Audet, Wenguang Cao, Estella Moffat, Lauren Garnett, Kevin Tierney, Kaylie N. Tran, Alixandra Albietz, Kathy Manguiat, Geoff Soule, Alexander Bello, Robert Vendramelli, Jessica Lin, Yvon Deschambault, Wenjun Zhu, Heidi Wood, Samira Mubareka, David Safronetz, James E. Strong, Carissa Embury-Hyatt, Darwyn Kobasa
Publikováno v:
iScience, Vol 24, Iss 12, Pp 103530- (2021)
Summary: The golden hamster model of SARS-CoV-2 infection recapitulates key characteristics of COVID-19. In this work we examined the influence of the route of exposure, sex, and age on SARS-CoV-2 pathogenesis in hamsters. We report that delivery of
Externí odkaz:
https://doaj.org/article/1dddd0fc2f9b4f73a788f89eb812218d
Autor:
Nikesh Tailor, Bryce M. Warner, Bryan D. Griffin, Kevin Tierney, Estella Moffat, Kathy Frost, Robert Vendramelli, Anders Leung, Marnie Willman, Sylvia P. Thomas, Yanlong Pei, Stephanie A. Booth, Carissa Embury-Hyatt, Sarah K. Wootton, Darwyn Kobasa
Publikováno v:
Viruses, Vol 15, Iss 1, p 85 (2022)
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the aetiological agent of coronavirus disease 2019 (COVID-19) that has caused a pandemic with millions of human infections. There continues to be a pressing need to develop potential the
Externí odkaz:
https://doaj.org/article/c282f1928b30468bada1eb6ce5ae4f2a
Autor:
Bryce M. Warner, Lisa A. Santry, Alexander Leacy, Mable Chan, Phuc H. Pham, Robert Vendramelli, Yanlong Pei, Nikesh Tailor, Emelissa Valcourt, Anders Leung, Shihua He, Bryan D. Griffin, Jonathan Audet, Marnie Willman, Kevin Tierney, Alixandra Albietz, Kathy L. Frost, Jacob G.E. Yates, Robert C. Mould, Lily Chan, Yeganeh Mehrani, Jason P. Knapp, Jessica A. Minott, Logan Banadyga, David Safronetz, Heidi Wood, Stephanie Booth, Pierre P. Major, Byram W. Bridle, Leonardo Susta, Darwyn Kobasa, Sarah K. Wootton
Publikováno v:
iScience, Vol 24, Iss 11, Pp 103219- (2021)
Summary: The pandemic severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the cause of coronavirus disease 2019 (COVID-19). Worldwide efforts are being made to develop vaccines to mitigate this pandemic. We engineered two recombinant Newc
Externí odkaz:
https://doaj.org/article/a9d6cd355eb7470ba0489696155667f5
Autor:
Ebony N. Gary, Bryce M. Warner, Elizabeth M. Parzych, Bryan D. Griffin, Xizhou Zhu, Nikesh Tailor, Nicholas J. Tursi, Mable Chan, Mansi Purwar, Robert Vendramelli, Jihae Choi, Kathy L. Frost, Sophia Reeder, Kevin Liaw, Edgar Tello, Ali R. Ali, Kun Yun, Yanlong Pei, Sylvia P. Thomas, Amira D. Rghei, Matthew M. Guilleman, Kar Muthumani, Trevor Smith, Sarah K. Wootton, Ami Patel, David B. Weiner, Darwyn Kobasa
Publikováno v:
iScience, Vol 24, Iss 7, Pp 102699- (2021)
Summary: More than 100 million people have been infected with severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2). Common laboratory mice are not susceptible to wild-type SARS-CoV-2 infection, challenging the development and testing of effec
Externí odkaz:
https://doaj.org/article/c729d41c6d47484fbcc09aab37def4d6
Autor:
Guillaume Poliquin, Duane Funk, Shane Jones, Kaylie Tran, Charlene Ranadheera, Mable Hagan, Kevin Tierney, Allen Grolla, Amrinder Dhaliwal, Alexander Bello, Anders Leung, Cory Nakamura, Darwyn Kobasa, Darryl Falzarano, Lauren Garnett, Hugues Fausther Bovendo, Heinz Feldmann, Murray Kesselman, Gregory Hansen, Jason Gren, George Risi, Mia Biondi, Todd Mortimer, Trina Racine, Yvon Deschambault, Sam Aminian, Jocelyn Edmonds, Ray Sourette, Mark Allan, Lauren Rondeau, Sharron Hadder, Christy Press, Christine DeGraff, Stephanie Kucas, Bradley W. M. Cook, B. J. Hancock, Anand Kumar, Reeni Soni, Darryl Schantz, Jarrid McKitrick, Bryce Warner, Bryan D. Griffin, Xiangguo Qiu, Gary P. Kobinger, Dave Safronetz, Derek Stein, Todd Cutts, James Kenny, Geoff Soule, Robert Kozak, Steven Theriault, Liam Menec, Robert Vendramelli, Sean Higgins, Guodong Liu, Niaz Md Rahim, Samantha Kasloff, Angela Sloan, Shihua He, Nikesh Tailor, Michael Gray, James E. Strong
Publikováno v:
Intensive Care Medicine Experimental, Vol 7, Iss 1, Pp 1-13 (2019)
Abstract Background There are currently limited data for the use of specific antiviral therapies for the treatment of Ebola virus disease (EVD). While there is anecdotal evidence that supportive care may be effective, there is a paucity of direct exp
Externí odkaz:
https://doaj.org/article/877aaa5f56994221966d8a8be6302d4a