Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Robert V. Bruggner"'
Autor:
Sean C. Bendall, Connie J. Eaves, Robert V. Bruggner, Gabriela K. Fragiadakis, Nikolay Samusik, Pier Federico Gherardini, Karen Sachs, Erin F. Simonds, William A. Weiss, Garry P. Nolan, Brice Gaudilliere, Martin S. Angst, Anthony Culos, David J.H.F. Knapp, Nima Aghaeepour, Wendy J. Fantl
Publikováno v:
Bioinformatics (Oxford, England), vol 34, iss 23
Motivation High-parameter single-cell technologies can reveal novel cell populations of interest, but studying or validating these populations using lower-parameter methods remains challenging. Results Here, we present GateFinder, an algorithm that e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a4671bb5d57a349e737457536f3c1473
https://hdl.handle.net/2108/312261
https://hdl.handle.net/2108/312261
Autor:
Michael D. Linderman, Robert V. Bruggner, Garry P. Nolan, Teresa H. Meng, Narges Bani Asadi, Vivek R. Athalye
Publikováno v:
ICS
Aberrant intracellular signaling plays an important role in many diseases. The causal structure of signal transduction networks can be modeled as Bayesian Networks (BNs), and computationally learned from experimental data. However, learning the struc
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Elucidation and examination of cellular subpopulations that display condition-specific behavior can play a critical contributory role in understanding disease mechanism, as well as provide a focal point for development of diagnostic criteria linking
Autor:
Sergio Verjovski-Almeida, James E. Galagan, Ryan C. Kennedy, Zhiyong Xi, Jason R. Miller, Eric Eisenstadt, Kyanne R. Reidenbach, Robert V. Bruggner, Yu-Hui Rogers, Hadi Quesneville, Doreen Werner, Owen White, Alexander S. Raikhel, Mario Stanke, J. Spencer Johnston, Diane D. Lovin, Evgenia V. Kriventseva, Ian T. Paulsen, Kathryn S. Campbell, Norman H. Lee, Ewan Birney, Karyn Megy, Hean Koo, David Kulp, Shelby L. Bidwell, Jingsong Zhu, Philip Montgomery, Paolo Amedeo, Yongmei Zhao, Chinnappa D. Kodira, Javier Costas, Michael C. Schatz, Steven P. Sinkins, Claire M. Fraser-Liggett, Martin Shumway, Kurt LaButti, Akio Mori, Brendan J. Loftus, Manfred Grabherr, Eric O. Stinson, Frank H. Collins, Zhijian Jake Tu, Monique R. Coy, Matt Crawford, Janice P. Vanzee, William M. Gelbart, Joshua Orvis, Peter Arensburger, Chunhong Mao, Evgeny M. Zdobnov, Saul A. Kravitz, Suely Lopes Gomes, David DeCaprio, David G. Hogenkamp, Daniel Lawson, Dennis L. Knudson, David W. Severson, George Dimopoulos, Marcelo B. Soares, Sinéad B. O'Leary, Peter W. Atkinson, David M. Jaffe, Becky deBruyn, Martin Hammond, Ana L. T. O. Nascimento, Jim Biedler, Stefan Wyder, Jose M. C. Tubio, Bruce W. Birren, Catherine A. Hill, Chad Nusbaum, Eduardo Lee, Song Li, Susan E. Brown, Jennifer R. Wortman, James R. Hogan, Hamza El-Dorry, Qi Zhao, Linda Hannick, Carlos Frederico Martins Menck, Vishvanath Nene, Jonathan Crabtree, Steven L. Salzberg, Michael H. Holmes, Maria de Fatima Bonaldo, Quinghu Ren, Mihaela Pertea, Charles Roth, Evan Mauceli, Karin Eiglmeier, Horacio Naveira, Brian J. Haas, Qiandong Zeng, Neil F. Lobo, Jennifer R. Schneider
Publikováno v:
Science
Science, American Association for the Advancement of Science, 2007, 316 (5832), pp.1718-23. 〈10.1126/science.1138878〉
Science, American Association for the Advancement of Science, 2007, 316 (5832), pp.1718-23. ⟨10.1126/science.1138878⟩
Science, 2007, 316 (5832), pp.1718-23. ⟨10.1126/science.1138878⟩
Science, Vol. 316, No 5832 (2007) pp. 1718-1723
Science, American Association for the Advancement of Science, 2007, 316 (5832), pp.1718-23. 〈10.1126/science.1138878〉
Science, American Association for the Advancement of Science, 2007, 316 (5832), pp.1718-23. ⟨10.1126/science.1138878⟩
Science, 2007, 316 (5832), pp.1718-23. ⟨10.1126/science.1138878⟩
Science, Vol. 316, No 5832 (2007) pp. 1718-1723
We present a draft sequence of the genome of Aedes aegypti , the primary vector for yellow fever and dengue fever, which at ∼1376 million base pairs is about 5 times the size of the genome of the malaria vector Anopheles gambiae . Nearly 50% of the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::701bca49fefccd61cb20d80a44096035
https://doi.org/10.1126/science.1138878
https://doi.org/10.1126/science.1138878
Autor:
Peter O. Krutzik, Karen Sachs, Rachel Finck, Eli R. Zunder, Robert V. Bruggner, Bernd Bodenmiller, Erin F. Simonds, Erica S. Savig, Garry P. Nolan, Tiffany J. Chen, Sean C. Bendall
Publikováno v:
Nature Biotechnology. 30:858-867
The ability to comprehensively explore the impact of bio-active molecules on human samples at the single-cell level can provide great insight for biomedical research. Mass cytometry enables quantitative single-cell analysis with deep dimensionality,
Autor:
Garry P. Nolan, Peng Qiu, Sean C. Bendall, Karen Sachs, Kenneth D. Gibbs, Robert V. Bruggner, Erin F. Simonds, Sylvia K. Plevritis, Michael D. Linderman
Publikováno v:
Nature biotechnology
Multiparametric single-cell analysis is critical for understanding cellular heterogeneity. Despite recent technological advances in single-cell measurements, methods for analyzing high-dimensional single-cell data are often subjective, labor intensiv
Autor:
Daniel Gerlach, Reed M. Johnson, Granger G. Sutton, Si Hyeock Lee, Didier Raoult, Hongmei Li, Weilin Sun, Robert V. Bruggner, Greg Madey, NaiKuan Wang, Ryan C. Kennedy, Joseph P. Strycharz, David L. Reed, Hugh M. Robertson, Stephen C. Barker, Ewen F. Kirkness, Jeanne Romero-Severson, Montserrat Aguadé, Janice P. Vanzee, Scott Christley, Emily C. Kraus, Frank H. Collins, Brian J. Haas, Shelby L. Bidwell, Evgenia V. Kriventseva, Stephen L. Cameron, Omprakash Mittapalli, Justin Johnson, J. Craig Venter, Venu M. Margam, Julio Rozas, Aleksandar Popadić, Juan Manuel Anzola, Yoshinori Tomoyasu, Jan A. Veenstra, Catherine A. Hill, Evgeny M. Zdobnov, Jose M. C. Tubio, Allison A. Regier, Elisabet Caler, Christine G. Elsik, Claudio J. Struchiner, David Alvarez-Ponce, Dan Graur, Gregory A. Dasch, Manfredo J. Seufferheld, Brian P. Walenz, Barry R. Pittendrigh, Linda Hannick, Robert L. Strausberg, Henk R. Braig, Renfu Shao, Sara Guirao-Rico, Neil F. Lobo, Justin T. Reese, Robert M. Waterhouse, Jason M. Meyer, José M. C. Ribeiro, Marta Tojo, M. Alejandra Perotti, John M. Clark, Eran Elhaik, Lakshmi D. Viswanathan, Filipe G. Vieira, Kyong Sup Yoon, J. Spencer Johnston, May R. Berenbaum, Daniel Lawson, Maria F. Unger, T. Utterback, Vinita Joardar
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Proceedings of the National Academy of Sciences, Vol. 107, No 27 (2010) pp. 12168-12173
Proceedings of the National Academy of Sciences, Vol. 107, No 27 (2010) pp. 12168-12173
As an obligatory parasite of humans, the body louse ( Pediculus humanus humanus ) is an important vector for human diseases, including epidemic typhus, relapsing fever, and trench fever. Here, we present genome sequences of the body louse and its pri
Publikováno v:
Infection, Genetics and Evolution. 9:308-313
High-throughput genome sequencing techniques have now reached vector biology with an emphasis on those species that are vectors of human pathogens. The first mosquito to be sequenced was Anopheles gambiae, the vector for Plasmodium parasites that cau
Autor:
William M. Gelbart, Fotis C. Kafatos, Robert V. Bruggner, Peter W. Atkinson, Ryan Butler, Nora J. Besansky, Karyn Megy, Scott Christley, Frank H. Collins, Peter Arensburger, Jason M. Meyer, Daniel Lawson, George K. Christophides, Robert M. MacCallum, Nathan Konopinski, Pantelis Topalis, Martin Hammond, Catherine A. Hill, Gregory R. Madey, Emmanuel Dialynas, Kathryn S. Campbell, Eric O. Stinson, David W. Severson, Christos Louis, Neil F. Lobo, Seth Redmond, Ewan Birney
Publikováno v:
Nucleic Acids Research
VectorBase (http://www.vectorbase.org) is an NIAID-funded Bioinformatic Resource Center focused on invertebrate vectors of human pathogens. VectorBase annotates and curates vector genomes providing a web accessible integrated resource for the researc
Autor:
Rachel Finck, James I. Huddleston, Robert V. Bruggner, Garry P. Nolan, William J. Maloney, Martha Tingle, Gabriela K. Fragiadakis, Martin S. Angst, Stuart B. Goodman, Monica Nicolau, Julian Silva, Wendy J. Fantl, Mark M. Davis, Brice Gaudilliere, Christine G. Yeh, Edward A. Ganio, Sean C. Bendall
Publikováno v:
Science Translational Medicine. 6
Delayed recovery from surgery causes personal suffering and substantial societal and economic costs. Whether immune mechanisms determine recovery after surgical trauma remains ill-defined. Single-cell mass cytometry was applied to serial whole-blood