Zobrazeno 1 - 8 of 8 pro vyhledávání: '"Robert Thomas Forbes"'
1
A Combined Rheological and Thermomechanical Analysis Approach for the Assessment of Pharmaceutical Polymer Blends
Autor: Mohammad Isreb, Marianiki Chalkia, Timothy Gough, Robert Thomas Forbes, Peter Timmins
Publikováno v: Polymers; Volume 14; Issue 17; Pages: 3527
Polymers
The viscoelastic nature of polymeric formulations utilised in drug products imparts unique thermomechanical attributes during manufacturing and over the shelf life of the product. Nevertheless, it adds to the challenge of understanding the precise me
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ef569a0177d3c0e5ef0874b5f3017bd
https://pubmed.ncbi.nlm.nih.gov/36080602
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2
Aromatic Stacking Facilitated Self-Assembly of Ultrashort Ionic Complementary Peptide Sequence: β-Sheet Nanofibers with Remarkable Gelation and Interfacial Properties
Autor: Jacek K. Wychowaniec, Rachel Thelma Mathomes, Yogita Patil-Sen, James Leach, Mohamed A. Elsawy, Robert Thomas Forbes, Joseph Hayes, Ronak Y. Patel, Araida Hidalgo-Bastida, Vikesh Chhabria
Publikováno v: Wychowaniec, J K, Patel, R, Leach, J, Mathomes, R, Chhabria, V, Patil-sen, Y, Hidalgo-bastida, A, Forbes, R T, Hayes, J M & Elsawy, M A 2020, ' Aromatic stacking facilitated self-assembly of ultra-short ionic complementary peptide sequence: β-sheet nanofibres with remarkable gelation and interfacial properties ', Biomacromolecules . https://doi.org/10.1021/acs.biomac.0c00366
open access article Understanding peptide self-assembly mechanisms and stability of the formed assemblies is crucial for the development of functional nanomaterials. Herein, we have adopted a rational design approach to demonstrate how a minimal stru
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3
Additive manufacturing of a point-of-care 'polypill': Fabrication of concept capsules of complex geometry with bespoke release against cardiovascular disease
Autor: Beatriz C. Pereira, Abdullah Isreb, Enoche Florence Oga, Robert Thomas Forbes, Mohammad Isreb, Mohamed Albed Alhnan
Publikováno v: Pereira, B C, Isreb, A, Isreb, M, Forbes, R T, Oga, E F & Alhnan, M A 2020, ' Additive Manufacturing of a Point-of-Care “Polypill:” Fabrication of Concept Capsules of Complex Geometry with Bespoke Release against Cardiovascular Disease ', Advanced Healthcare Materials, vol. 9, no. 13, 2000236 . https://doi.org/10.1002/adhm.202000236
Polypharmacy is often needed for the management of cardiovascular diseases and is associated with poor adherence to treatment. Hence, highly flexible and adaptable systems are of in high demand to accommodate complex therapeutic regimens. A novel des
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4
Tailored on demand anti-coagulant dosing: An in vitro and in vivo evaluation of 3D printed purpose-designed oral dosage forms
Autor: Robert Thomas Forbes, Mohamed Albed Alhnan, Milena Cieszynska, Nidal A. Qinna, Basel Arafat
Publikováno v: European Journal of Pharmaceutics and Biopharmaceutics. 128:282-289
Coumarin therapy has been associated with high levels of inter- and intra-individual variation in the required dose to reach a therapeutic anticoagulation outcome. Therefore, a dynamic system that is able to achieve accurate delivery of a warfarin do
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e8dc70834a6a82c6605f98b7d7f243a
https://doi.org/10.1016/j.ejpb.2018.04.010
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5
Channelled tablets: An innovative approach to accelerating drug release from 3D printed tablets
Autor: Robert Thomas Forbes, Waqar Ahmed, Muzna Sadia, Mohamed Albed Alhnan, Basel Arafat
Publikováno v: Journal of Controlled Release. 269:355-363
Conventional immediate release dosage forms involve compressing the powder with a disintegrating agent that enables rapid disintegration and dissolution upon oral ingestion. Among 3D printing technologies, the fused deposition modelling (FDM) 3D prin
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f1ddefdf6d4e8129190563d8608beed
https://doi.org/10.1016/j.jconrel.2017.11.022
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6
‘Temporary Plasticiser’: A Novel Solution to Fabricate 3D Printed Patient-Centred Cardiovascular ‘Polypill’ Architectures
Autor: Abdullah Isreb, Rober Habashy, Filipa Dores, Beatriz C. Pereira, Jean-Baptiste Petit, Mohamed Albed Alhnan, Enoche Florence Oga, Robert Thomas Forbes
Hypertension and dyslipidaemia are modifiable risk factors associated with cardiovascular diseases (CVDs) and often require a complex therapeutic regimen. The administration of several medicines is commonly associated with poor levels of adherence am
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8
Tablet fragmentation without a disintegrant: A novel design approach for accelerating disintegration and drug release from 3D printed cellulosic tablets
Autor: Robert Thomas Forbes, Waqar Ahmed, Mohammad Isreb, Abdullah Isreb, Mohamed Albed Alhnan, Magdalena Wojsz, Tawfiq Arafat, Basel Arafat
Fused deposition modelling (FDM) 3D printing has shown the most immediate potential for on-demand dose personalisation to suit particular patient's needs. However, FDM 3D printing often involves employing a relatively large molecular weight thermopla
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