Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Robert T.C. Ju"'
Publikováno v:
Journal of Pharmaceutical Sciences. 84:1455-1463
Two scaling laws for predicting polymer and drug release profiles from hydrophilic matrices were developed. They were developed on the basis of the diffusion layer and the polymer disentanglement concentration, rho p,dis, the critical polymer concent
Publikováno v:
Journal of pharmaceutical sciences. 86(11)
A semiempirical formula was developed for the diffusion coefficient, Dp, of polymer within the diffusion layer adjacent to a matrix undergoing swelling and dissolution. This formula of Dp was a key element in a comprehensive mathematical model that d
Publikováno v:
Journal of pharmaceutical sciences. 84(12)
A comprehensive model is developed to describe the swelling/dissolution behaviors and drug release from hydrophilic matrices. The major thrust of this model is to employ an important physical property of the polymer, the polymer disentanglement conce