Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Robert T. Youker"'
Publikováno v:
Journal of Respiration, Vol 1, Iss 3, Pp 204-215 (2021)
Cystic Fibrosis (CF) is caused by loss of function mutations in the Cystic Fibrosis transmembrane conductance regulator (CFTR). The folding and assembly of CFTR is inefficient. Deletion of F508 in the first nucleotide binding domain (NBD1-ΔF508) fur
Externí odkaz:
https://doaj.org/article/657a10d156a742af8015a7da946b5179
Publikováno v:
PeerJ, Vol 5, p e3492 (2017)
Understanding how proteins mutate is critical to solving a host of biological problems. Mutations occur when an amino acid is substituted for another in a protein sequence. The set of likelihoods for amino acid substitutions is stored in a matrix and
Externí odkaz:
https://doaj.org/article/1d235b16cb5845f0afc425289bfb8f39
Autor:
Danielle Voet, Robert T. Youker
Publikováno v:
Fluorescence Methods for Investigation of Living Cells and Microorganisms
Fluorescence Methods for Investigation of Living Cells and Microorganisms ISBN: 9781839680397
Fluorescence Methods for Investigation of Living Cells and Microorganisms ISBN: 9781839680397
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::33a194d8989bfb2da9426e2f40536629
http://www.intechopen.com/articles/show/title/fluorescence-fluctuation-techniques-for-the-investigation-of-structure-function-relationships-of-g-p
http://www.intechopen.com/articles/show/title/fluorescence-fluctuation-techniques-for-the-investigation-of-structure-function-relationships-of-g-p
Publikováno v:
Journal of Teaching and Learning, Vol 14, Iss 1 (2020)
The commercialization of Virtual Reality (VR) hardware has enabled the use of VR as an educational tool. We describe how a VR platform was used to create molecular visualizations using standard PDB files with the purpose of delivering biochemistry an
Autor:
Gabrianne Ivey, Robert T. Youker
Publikováno v:
PLoS ONE, Vol 15, Iss 2, p e0229986 (2020)
[This corrects the article DOI: 10.1371/journal.pone.0227668.].
Autor:
Gudrun Ihrke, Núria M. Pastor-Soler, Rebecca P. Hughey, Robert T. Youker, Simone A. Costa, Ora A. Weisz, Di Mo
Publikováno v:
Molecular Biology of the Cell
The sialomucin endolyn is implicated in adhesion, migration, and differentiation of various cell types. Apical delivery of endolyn requires recognition of sialic acids on its N-glycans possibly (or likely) mediated by galectin-9.
The sialomucin
The sialomucin
Autor:
Jennifer R. Bruns, Gudrun Ihrke, Rebecca P. Hughey, Robert T. Youker, Kerry O. Cresawn, Ora A. Weisz, Polly E. Mattila, Di Mo
Publikováno v:
Traffic. 13:433-442
Many newly synthesized membrane proteins traverse endocytic intermediates en route to the surface in polarized epithelial cells; however, the biosynthetic itinerary of secreted proteins has not been elucidated. We monitored the trafficking route of t
Publikováno v:
Biochemical Journal. 421:1-15
The endomembrane system in mammalian cells has evolved over the past two billion years from a simple endocytic pathway in a single-celled primordial ancestor to complex networks supporting multicellular structures that form metazoan tissue and organ
Autor:
Matthew H. Brush, Huihong You, Douglas N. Runckel, Joseph E. Aslan, Robert T. Youker, Laurel Thomas, Robert L. Milewski, Arndt Vogel, Jessica Endig, Hongjun Shu, Gary Thomas, Danielle M. Williamson, Haian Fu, Kam Sprott, Kenneth D. Greis, Yuhong Du, Anthony Possemato
Publikováno v:
Molecular Cell. 34:497-509
TRAIL selectively kills diseased cells in vivo, spurring interest in this death ligand as a potential therapeutic. However, many cancer cells are resistant to TRAIL, suggesting the mechanism mediating TRAIL-induced apoptosis is complex. Here we ident