Zobrazeno 1 - 10
of 87
pro vyhledávání: '"Robert T. LaLonde"'
Autor:
Mianji Zhang, Robert T. LaLonde
Publikováno v:
Journal of Natural Products. 67:697-699
Oxidation of alpha-conidendrin (3) by Fremy's salt favored formation of an o-quinone (4) at the pendant aromatic ring as opposed to the fused aromatic ring. Quinone reduction and phenolic methylation, followed by lactone reduction, and subsequent oxi
Autor:
Howard R. Leo, Robert T. LaLonde
Publikováno v:
Chemical Research in Toxicology. 7:779-783
Both bromine- and chlorine-substituted 2(5H)-furanones are produced by the chlorination of ligno-humic waters containing bromide ion. The molar mutagenicities of four bromine- and chlorine-substituted 2(5H)-furanones were determined by the Salmonella
Autor:
Shan Xie, Robert T. LaLonde
Publikováno v:
Chemical Research in Toxicology. 5:618-624
The Salmonella typhimurium (TA100) mutagenic compound, mucochloric acid [3,4-dichloro-5-hydroxy-2(5H)-furanone (MCA)], was inactivated by in vitro N-acetylcysteine (NAC). The reaction of MCA with NAC at pH7 was second order and gave products 4, 5, an
Publikováno v:
Chemical Research in Toxicology. 5:392-400
Electrophilicity as a general basis for both the mutagenicity and nucleophile inactivation of halogen-substituted 2(5H)-furanones was tested. Lowest unoccupied molecular orbital (LUMO) energy levels and stabilities of 2(5H)-furanone radical anions an
Publikováno v:
Chemical Research in Toxicology. 4:540-545
The Salmonella typhimurium (TA100) mutagenicities of six structural analogues of 3-chloro-4-(dichloromethyl)-5-hydroxy-2(5H)-furanone (MX) were determined and compared. These were also compared to previously determined mutagenicities for another four
Autor:
Robert T. Lalonde, Gary P. Cook, Hannu Perakyla, Carlton W. Dence, John G. Babish, J. H. Carver
Publikováno v:
Environmental and Molecular Mutagenesis. 17:40-48
The mutagenicities of 3-chloro-4-(dichloromethyl)-5-hydroxy-2(5H)-furanone (MX, compound 1), 3-chloro-4-(dichloromethyl)-2(5H)-furanone (RMX, compound 6), and 2-(dichloromethyl)-3,3-dichloropropenal (TCB, compound 7) were determined in the same assay
Publikováno v:
The Journal of Organic Chemistry. 64:4607-4609
Positional preferences for para benzylic oxygenation of tetrahydronaphthalenes by 2,3-dichloro-5,6-dicyano-1,4-benzoquinone (DDQ)-aqueous dioxane were investigated by comparing the tetralone products from 6-hydroxy-7-methoxy- and 6-acetoxy-7-methoxy-
Publikováno v:
Environmental Toxicology and Chemistry. 9:687-691
The sodium borohydride reduction of 3,4-dichloro-5-hydroxy-2(5H)-furanone (mucochloric acid) resulted in the formation of 3,4-dichloro-2(5H)-furanone and 4-chloro-2(5H)-furanone formed in relative amounts of 98 and 2%, respectively. Mucochloric acid
Publikováno v:
The Journal of Organic Chemistry. 55:2847-2855
The mutagen 3-chloro-4-(dichloromethyl)-5-hydroxy-2(5H)-furanone (MX), 1, and seven analogues of it were synthesized from 4-(hydroxymethyl)-2(5H)-furanone, 2
Autor:
Robert T. LaLonde
Publikováno v:
Van Nostrand's Encyclopedia of Chemistry
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::af9fb9118af1aac8066b5d35eff9d210
https://doi.org/10.1002/0471740039.vec2473
https://doi.org/10.1002/0471740039.vec2473