Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Robert T. Elder"'
Publikováno v:
BioTechniques, Vol 25, Iss 3, Pp 438-444 (1998)
A pYZ series of fission yeast expression vectors, derivatives of the pREP series, was designed to allow positive identification of cloned gene insertion and fusion to the green fluorescent protein (GFP) gene for in vivo analysis of gene expression. T
Externí odkaz:
https://doaj.org/article/086c8e7911d243a89618b672e538109c
Publikováno v:
PLoS ONE, Vol 11, Iss 3, p e0151286 (2016)
BACKGROUND:HIV-1 protease (PR) is an essential viral enzyme. Its primary function is to proteolyze the viral Gag-Pol polyprotein for production of viral enzymes and structural proteins and for maturation of infectious viral particles. Increasing evid
Externí odkaz:
https://doaj.org/article/8248cff04f9f4b0691ff34430f572a9d
Autor:
Ge Li, Robert T Elder, Larisa Dubrovsky, Dong Liang, Tatiana Pushkarsky, Karen Chiu, Tao Fan, Josephine Sire, Michael Bukrinsky, Richard Y Zhao
Publikováno v:
PLoS ONE, Vol 5, Iss 6, p e11371 (2010)
HIV-1 Vpr is a virion-associated protein. Its activities link to viral pathogenesis and disease progression of HIV-infected patients. In vitro, Vpr moderately activates HIV-1 replication in proliferating T cells, but it is required for efficient vira
Externí odkaz:
https://doaj.org/article/313e82aa97d542b7932285f675fac46c
Autor:
Richard Y. Zhao, Timea Stromájer-Rácz, Eszter Virág, Zoltán Gazdag, Miklós Pesti, Robert T. Elder, Joseph Belagyi
Publikováno v:
Acta Biologica Hungarica. 66:326-338
The wild-type viral protein R (Vpr) of human immunodeficiency virus type 1 exerts multiple effects on cellular activities during infection, including the induction of cell cycle G2 arrest and the death of human cells and cells of the fission yeast Sc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e8d8a9e7a7449baaa68531260d7a782f
https://doi.org/10.1556/018.66.2015.3.8
https://doi.org/10.1556/018.66.2015.3.8
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Molecular Cell Research. 1746(2):155-162
A fission yeast (Schizosaccharomyces pombe) gene encoding a member of the TIP41-like protein family was identified and characterized. Deletion of the fission yeast tip41 gene leads to slower growth when ammonium chloride is the nitrogen source, but t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bebbbbdc1625b2f16b649b630ca94a3d
Publikováno v:
Virology. 287:359-370
Viral protein R (Vpr) of human immunodeficiency virus type 1 induces G2 arrest in cells from distantly related eukaryotes including human and fission yeast through inhibitory phosphorylation of tyrosine 15 (Tyr15) on Cdc2. Since the DNA damage and DN
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ebe7c7dfb8efa72af422c02b109d020d
https://doi.org/10.1006/viro.2001.1007
https://doi.org/10.1006/viro.2001.1007
Publikováno v:
International Journal of High Throughput Screening.
Zsigmond Benko1, Robert T Elder2, Dong Liang1, Richard Y Zhao11Department of Pathology, Department of Microbiology-Immunology, Institute of Human Virology, University of Maryland Medical School, Baltimore, MD, USA; 2Children’s Memorial Research Cen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a9a4ae418ef592920a0557671c0a983
https://www.dovepress.com/fission-yeast-as-a-hts-platform-for-molecular-probes-of-hiv-1-vpr-indu-peer-reviewed-article-IJHTS
https://www.dovepress.com/fission-yeast-as-a-hts-platform-for-molecular-probes-of-hiv-1-vpr-indu-peer-reviewed-article-IJHTS
Autor:
Karen Chiu, Dong Liang, Joséphine Sire, Ge Li, Richard Y. Zhao, Tatiana Pushkarsky, Michael Bukrinsky, Tao Fan, Robert T. Elder, Larisa Dubrovsky
Publikováno v:
PLoS ONE, Vol 5, Iss 6, p e11371 (2010)
PLoS ONE
PLoS ONE
HIV-1 Vpr is a virion-associated protein. Its activities link to viral pathogenesis and disease progression of HIV-infected patients. In vitro, Vpr moderately activates HIV-1 replication in proliferating T cells, but it is required for efficient vira
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b2886bdd3f51c6281f45ee8fab27e23
http://europepmc.org/articles/PMC2894085?pdf=render
http://europepmc.org/articles/PMC2894085?pdf=render
Autor:
Min Yu, Kristen E Burdette, Csaba Fenyvuesvolgyi, Robert T. Elder, Sylvain Huard, Mingzhong Chen, Richard Y. Zhao
Publikováno v:
Cell research. 18(9)
Human immunodeficiency virus type 1 (HIV-1) Vpr induces cell death in mammalian and fission yeast cells, suggesting that Vpr may affect a conserved cellular process. It is unclear, however, whether Vpr-induced yeast cell death mimics Vpr-mediated apo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e140605f5a8ccd96a1f0b6d2a172d6c1
https://pubmed.ncbi.nlm.nih.gov/19160543
https://pubmed.ncbi.nlm.nih.gov/19160543
Human immunodeficiency virus type 1 (HIV-1) viral protein R (Vpr) is a virion-associated accessory protein with an average length of 96 amino acids and a calculated molecular mass of 12.7 kDa (14). Increasing evidence suggests that Vpr plays an impor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::282816e3039de9c0339de5c96380c9b5
https://europepmc.org/articles/PMC2259012/
https://europepmc.org/articles/PMC2259012/
