Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Robert T. Buckler"'
Publikováno v:
Clinical Chemistry. 27:22-26
A substrate-labeled fluorescent immunoassay for theophylline in serum is described. 8-(3-Aminopropyl)-theophylline is covalently attached to a fluorogenic enzyme substrate, 7-beta-galactosylcoumarin-3-carboxylic acid. Hydrolysis of this theophylline-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7f4a4042b54502785cd757d15083a1e4
https://doi.org/10.1093/clinchem/27.1.22
https://doi.org/10.1093/clinchem/27.1.22
Publikováno v:
Journal of Medicinal Chemistry. 24:1073-1077
The antimicrobial activity previously attributed to flavanone Mannich bases was found to be due to their breakdown products, 3-methyleneflavanones. Among the latter compounds, highest potency was observed when the flavanone phenyl ring contained brom
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb3442ab0bf8d20b2533731ac4a43678
https://doi.org/10.1021/jm00141a011
https://doi.org/10.1021/jm00141a011
Publikováno v:
Analytical Chemistry. 48:1933-1937
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::08d1b400e9eff842a3f0f4fc64efff83
https://doi.org/10.1021/ac50007a032
https://doi.org/10.1021/ac50007a032
Publikováno v:
Clinical Chemistry. 29:1051-1056
This assay system for simultaneously determining phenytoin and phenobarbital in serum and plasma is based on the substrate-labeled fluorescent immunoassay technique. A beta-galactosylcoumarin derivative of phenobarbital and a 4-methylcoumarin phospho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7bf1c167991ea261d6947ec11f685a56
https://doi.org/10.1093/clinchem/29.6.1051
https://doi.org/10.1093/clinchem/29.6.1051
Autor:
Robert C. Boguslaski, Robert J. Carrico, James Edward Christner, Robert T. Buckler, Hartmut R. Schroeder, Kwok-Kam Yeung
Publikováno v:
Analytical Biochemistry. 76:95-110
A new method was developed to monitor specific protein binding reactions with an ATP-labeled ligand and firefly luciferase. The ligand, 2,4-dinitrobenzene, was covalently coupled to four ATP derivatives and three of these conjugates were measured qua
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f73e0194661530132a5cca23d1ecea43
https://doi.org/10.1016/0003-2697(76)90267-0
https://doi.org/10.1016/0003-2697(76)90267-0
Autor:
Robert T. Buckler, David L. Garling
Publikováno v:
Tetrahedron Letters. 19:2257-2260
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e69150d8e8c7ecc9dd3a6be5cb2b2857
https://doi.org/10.1016/s0040-4039(01)91506-0
https://doi.org/10.1016/s0040-4039(01)91506-0
Autor:
Frederick E. Ward, Robert T. Buckler
Publikováno v:
The Journal of Organic Chemistry. 45:4608-4611
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ff5c9cbf694a2e1cc43ac3b7354b5938
https://doi.org/10.1021/jo01311a012
https://doi.org/10.1021/jo01311a012
Publikováno v:
Journal of Medicinal Chemistry. 18:509-513
A series of 34 beta-arylamidoacrylic acids was prepared and examined for antiinflammatory activity. These compounds are vinylogous carbamic acids, and several displayed activity equal to phenylbutazone in the rat pleural effusion model. Highest activ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18d09066232869390863c71d20604fba
https://doi.org/10.1021/jm00239a015
https://doi.org/10.1021/jm00239a015
Publikováno v:
Clinical Chemistry. 25:686-691
A homogeneous substrate-labeled fluorescent immunoassay has been applied to the measurement of phenytoin concentrations in human serum. We coupled a fluorogenic enzyme substrate, galactosyl-umbelliferone, covalently to a derivative of phenytoin. Unde
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::25680121b17d25d78a45b612bda78360
https://doi.org/10.1093/clinchem/25.5.686
https://doi.org/10.1093/clinchem/25.5.686
Autor:
Olfeo J. Lorenzetti, Wallace Glenn Strycker, Shin Hayao, L. F. Sancilio, Harold E. Hartzler, Robert T. Buckler
Publikováno v:
Journal of Medicinal Chemistry. 13:725-729
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b754d0e6d9c5d19c75cdbcae475413c
https://doi.org/10.1021/jm00298a032
https://doi.org/10.1021/jm00298a032