Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Robert T. Breckenridge"'
Publikováno v:
The Journal of Immunology. 120:9-14
Analysis of the zymosan (Z)-induced human platelet response with washed platelets, fresh agammaglobulinemic plasma, and purified human IgG has identified a previously unrecognized role of IgG in this reaction, in addition to the previously reported r
Publikováno v:
Blood. 46:189-197
Plasma proteins which interfere with blood coagulation have often been described in patients with systemic lupus erythematosus (SLE). The most frequent type interferes with the conversion of prothrombin to thrombin and thus prolongs the prothrombin t
Publikováno v:
Blood. 20:137-149
Modification of the kaolin clotting time has produced a reliable, simple assay system for antihemophilic factor. This system has been utilized for an investigation of the nature and mode of action of the circulating anticoagulant directed against ant
Publikováno v:
British Journal of Haematology. 13:898-914
SUMMARY An incubation mixture of activated Stuart factor, calcium, phospholipid and proaccelerin caused the generation of thrombin from prothrombin. The activity of this prothrombin- converting principle was measured by the rate at which it converted
Autor:
Robert T. Breckenridge, Leon W. Hoyer
Publikováno v:
Blood. 32:962-971
Immunologic studies have identified two genetically distinct types of hemophilia A. While a majority of patients apparently fail to synthesize AHF, a variant has been recognized in which a nonfunctional but antigenically cross-reacting AHF-like prote
Autor:
Leon W. Hoyer, Robert T. Breckenridge
Publikováno v:
Blood. 35:809-820
Patients with a genetic variant of hemophilia A have in their plasmas material which has antigenic characteristics similar to those of antihemophilic factor (AHF). The physical properties of the biologically inactive cross-reacting material (CRM) are
Publikováno v:
Blood. 30:39-53
Sixty-nine cases of thrombocytopenia in which splenectomy had been performed have been reviewed. New cytological criteria are described for the diagnosis of disseminated lupus erythematosus by the examination of the splenic tissue. Six cases of throm
Publikováno v:
Blood. 27:527-536
Through the kindness of Dr. J. H. Milstone we were able to perform clotting studies with purified bovine thrombokinase. Phenylmethyl sulfonylfluoride was found to inactivate bovine thrombin. Bovine thrombokinase, freed of traces of contaminating thro
Publikováno v:
The American Journal of Medicine. 35:813-819
A circulating anticoagulant found in lupus erythematosus and certain other states has been studied by means of a sequential clotting system utilizing crude clotting factors to convert prothrombin to thrombin. These studies demonstrate that the antico
Autor:
Robert T. Breckenridge
Publikováno v:
The American Journal of the Medical Sciences. 263:275-280