Zobrazeno 1 - 10
of 141
pro vyhledávání: '"Robert T Clubb"'
Autor:
Michele D Kattke, Jason E Gosschalk, Orlando E Martinez, Garima Kumar, Robert T Gale, Duilio Cascio, Michael R Sawaya, Martin Philips, Eric D Brown, Robert T Clubb
Publikováno v:
PLoS Pathogens, Vol 15, Iss 4, p e1007723 (2019)
Staphylococcus aureus and other bacterial pathogens affix wall teichoic acids (WTAs) to their surface. These highly abundant anionic glycopolymers have critical functions in bacterial physiology and their susceptibility to β-lactam antibiotics. The
Externí odkaz:
https://doaj.org/article/7f0a8bf7318548a9bcafd1c36499c5bd
Autor:
Michele D Kattke, Albert H Chan, Andrew Duong, Danielle L Sexton, Michael R Sawaya, Duilio Cascio, Marie A Elliot, Robert T Clubb
Publikováno v:
PLoS ONE, Vol 11, Iss 12, p e0167763 (2016)
Many species of Gram-positive bacteria use sortase transpeptidases to covalently affix proteins to their cell wall or to assemble pili. Sortase-displayed proteins perform critical and diverse functions for cell survival, including cell adhesion, nutr
Externí odkaz:
https://doaj.org/article/1db9d06ae8d24b11b2dbb3eb13673102
Autor:
Christopher K. Sue, Nicole A. Cheung, Brendan J. Mahoney, Scott A. McConnell, Jack M. Scully, Janine Y. Fu, Chungyu Chang, Hung Ton-That, Joseph A. Loo, Robert T. Clubb
Publikováno v:
bioRxiv
Many species of pathogenic gram-positive bacteria display covalently crosslinked protein polymers (called pili or fimbriae) that mediate microbial adhesion to host tissues. These structures are assembled by pilus-specific sortase enzymes that join th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::206654ed6d28a52e3139e686c80ebd96
https://europepmc.org/articles/PMC9980135/
https://europepmc.org/articles/PMC9980135/
Autor:
Ramsay Macdonald, Brendan J. Mahoney, Jess Soule, Andrew K. Goring, Jordan Ford, Joseph A. Loo, Duilio Cascio, Robert T. Clubb
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America, vol 120, iss 5
Streptococcus pyogenes (group A Streptococcus ) is a clinically important microbial pathogen that requires iron in order to proliferate. During infections, S. pyogenes uses the surface displayed Shr receptor to capture human hemoglobin (Hb) and acqui
Publikováno v:
Proteins
Clostridium thermocellum is actively being developed as a microbial platform to produce biofuels and chemicals from renewable plant biomass. An attractive feature of this bacterium is its ability to efficiently degrade lignocellulose using surface-di
Autor:
Debjit Roy, Xavier Michalet, Kiran Bharadwaj, Evan W. Miller, Yijie Wang, Arjun Deb, Michael A. Wayne, Claudio Bruschini, Edoardo Charbon, Mahbanoo Vakili, Robert Gunsalus, Robert T. Clubb, Shimon Weiss
Publikováno v:
Biophysical Journal. 122:176a
Autor:
Joseph Clayton, Kat Ellis-Guardiola, Brendan Mahoney, Jess Soule, Robert T. Clubb, Jeff Wereszczynski
Pathogenic Staphylococcus aureus actively acquires iron from human hemoglobin (Hb) using the IsdH surface receptor. Heme extraction is mediated by a tridomain unit within the receptor that contains its second (N2) and third (N3) NEAT domains joined b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a67c759f0e7b837d15f062da7980bc7d
https://doi.org/10.1101/2021.12.28.474365
https://doi.org/10.1101/2021.12.28.474365
Autor:
Orlando E. Martinez, Xi Chen, Duilio Cascio, Robert T. Clubb, Michael E. Jung, Joseph A. Loo, Sung-Wook Yi, Musleh M. Muthana, Brendan J. Mahoney, Andrew K. Goring, Denise P. Tran, Martin L. Phillips
Publikováno v:
The Journal of Biological Chemistry
The Journal of biological chemistry, vol 298, iss 2
The Journal of biological chemistry, vol 298, iss 2
Wall teichoic acid (WTA) polymers are covalently affixed to the Gram-positive bacterial cell wall and have important functions in cell elongation, cell morphology, biofilm formation, and β-lactam antibiotic resistance. The first committed step in WT
Autor:
Chungyu Chang, Jerzy Osipiuk, Sara D. Siegel, Shiwei Zhu, Andrzej Joachimiak, Robert T. Clubb, Chenggang Wu, Xiangan Liu, Asis Das, Hung Ton-That
Publikováno v:
Proceedings of the National Academy of Sciences. 116:18041-18049
Assembly of pili on the gram-positive bacterial cell wall involves 2 conserved transpeptidase enzymes named sortases: One for polymerization of pilin subunits and another for anchoring pili to peptidoglycan. How this machine controls pilus length and
Autor:
Brendan J. Mahoney, Ken Ellis-Guardiola, Ramsay Macdonald, Robert T. Clubb, Anthony William Maresso
Publikováno v:
Protein Sci
Iron is a versatile metal cofactor that is used in a wide range of essential cellular processes. During infections, many bacterial pathogens acquire iron from human hemoglobin (Hb), which contains the majority of the body's total iron content in the