Zobrazeno 1 - 10
of 141
pro vyhledávání: '"Robert T, Clubb"'
Autor:
Hui S. Tsui, NguyenV.B. Pham, Brendan R. Amer, Michelle C. Bradley, Jason E. Gosschalk, Marcus Gallagher-Jones, Hope Ibarra, Robert T. Clubb, Crysten E. Blaby-Haas, Catherine F. Clarke
Publikováno v:
Journal of Lipid Research, Vol 60, Iss 7, Pp 1293-1310 (2019)
Coenzyme Q (CoQ or ubiquinone) serves as an essential redox-active lipid in respiratory electron and proton transport during cellular energy metabolism. CoQ also functions as a membrane-localized antioxidant protecting cells against lipid peroxidatio
Externí odkaz:
https://doaj.org/article/b7349ba5f90843f1bb6432c5f15a3f0b
Publikováno v:
Frontiers in Microbiology, Vol 11 (2021)
Iron is an important micronutrient that is required by bacteria to proliferate and to cause disease. Many bacterial pathogens forage iron from human hemoglobin (Hb) during infections, which contains this metal within heme (iron–protoporphyrin IX).
Externí odkaz:
https://doaj.org/article/0c61017d304d47718c09e5627675cd5e
Autor:
Michele D Kattke, Jason E Gosschalk, Orlando E Martinez, Garima Kumar, Robert T Gale, Duilio Cascio, Michael R Sawaya, Martin Philips, Eric D Brown, Robert T Clubb
Publikováno v:
PLoS Pathogens, Vol 15, Iss 4, p e1007723 (2019)
Staphylococcus aureus and other bacterial pathogens affix wall teichoic acids (WTAs) to their surface. These highly abundant anionic glycopolymers have critical functions in bacterial physiology and their susceptibility to β-lactam antibiotics. The
Externí odkaz:
https://doaj.org/article/7f0a8bf7318548a9bcafd1c36499c5bd
Autor:
Sara D. Siegel, Brendan R. Amer, Chenggang Wu, Michael R. Sawaya, Jason E. Gosschalk, Robert T. Clubb, Hung Ton-That
Publikováno v:
mBio, Vol 10, Iss 2 (2019)
Externí odkaz:
https://doaj.org/article/b9d1b7c32a82485d87e64bd426f97bdd
Autor:
Sara D. Siegel, Brendan R. Amer, Chenggang Wu, Michael R. Sawaya, Jason E. Gosschalk, Robert T. Clubb, Hung Ton-That
Publikováno v:
mBio, Vol 10, Iss 1 (2019)
ABSTRACT The widely conserved LytR-CpsA-Psr (LCP) family of enzymes in Gram-positive bacteria is known to attach glycopolymers, including wall teichoic acid, to the cell envelope. However, it is undetermined if these enzymes are capable of catalyzing
Externí odkaz:
https://doaj.org/article/012fcfa94d5c4b6d879eedef1c81d734
Autor:
Christopher K. Sue, Nicole A. Cheung, Brendan J. Mahoney, Scott A. McConnell, Jack M. Scully, Janine Y. Fu, Chungyu Chang, Hung Ton-That, Joseph A. Loo, Robert T. Clubb
Publikováno v:
bioRxiv
Many species of pathogenic gram-positive bacteria display covalently crosslinked protein polymers (called pili or fimbriae) that mediate microbial adhesion to host tissues. These structures are assembled by pilus-specific sortase enzymes that join th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::206654ed6d28a52e3139e686c80ebd96
https://europepmc.org/articles/PMC9980135/
https://europepmc.org/articles/PMC9980135/
Autor:
Ramsay Macdonald, Brendan J. Mahoney, Jess Soule, Andrew K. Goring, Jordan Ford, Joseph A. Loo, Duilio Cascio, Robert T. Clubb
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America, vol 120, iss 5
Streptococcus pyogenes (group A Streptococcus ) is a clinically important microbial pathogen that requires iron in order to proliferate. During infections, S. pyogenes uses the surface displayed Shr receptor to capture human hemoglobin (Hb) and acqui
Publikováno v:
Proteins
Clostridium thermocellum is actively being developed as a microbial platform to produce biofuels and chemicals from renewable plant biomass. An attractive feature of this bacterium is its ability to efficiently degrade lignocellulose using surface-di
Autor:
Debjit Roy, Xavier Michalet, Kiran Bharadwaj, Evan W. Miller, Yijie Wang, Arjun Deb, Michael A. Wayne, Claudio Bruschini, Edoardo Charbon, Mahbanoo Vakili, Robert Gunsalus, Robert T. Clubb, Shimon Weiss
Publikováno v:
Biophysical Journal. 122:176a
Autor:
Michele D Kattke, Albert H Chan, Andrew Duong, Danielle L Sexton, Michael R Sawaya, Duilio Cascio, Marie A Elliot, Robert T Clubb
Publikováno v:
PLoS ONE, Vol 11, Iss 12, p e0167763 (2016)
Many species of Gram-positive bacteria use sortase transpeptidases to covalently affix proteins to their cell wall or to assemble pili. Sortase-displayed proteins perform critical and diverse functions for cell survival, including cell adhesion, nutr
Externí odkaz:
https://doaj.org/article/1db9d06ae8d24b11b2dbb3eb13673102