Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Robert Szpera"'
Publikováno v:
Beilstein Journal of Organic Chemistry, Vol 13, Iss 1, Pp 2883-2887 (2017)
The diastereoselective synthesis of fluorinated building blocks that contain chiral fluorine substituents is of interest. Here we describe optimisation efforts in the synthesis of anti-2,3-difluorobutane-1,4-diol, as well as the synthesis of the corr
Externí odkaz:
https://doaj.org/article/21161b8923cc4b34bd071368d7fbf1f9
Autor:
Véronique Gouverneur, David C. Blakemore, Maxime Ghosez, Patrick G. Isenegger, Natan J. W. Straathof, Rosa Cookson, Paul G. Richardson, Robert Szpera
Publikováno v:
Organic Letters
Herein, we report a highly effective protocol for the cross-coupling of (hetero)aryl bromides with fluorinated alcohols using the commercially available precatalyst tBuBrettPhos Pd G3 and Cs2CO3 in toluene. This Pd-catalyzed coupling features a short
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::50dce21552554ed845a46a7a5647b211
https://doi.org/10.1021/acs.orglett.0c02347
https://doi.org/10.1021/acs.orglett.0c02347
Autor:
Bruno Linclau, Jean-Baptiste Vendeville, Clement Q. Fontenelle, Robert Szpera, Mark E. Light, Ramakrishna Kuppala, Edward L Briggs, David E Wheatley, Neil J. Wells
Protein-carbohydrate interactions are implicated in many biochemical/biological processes that are fundamental to life and to human health. Fluorinated carbohydrate analogues play an important role in the study of these interactions and find applicat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7084be9f42955cdf4ef449719b539715
https://eprints.soton.ac.uk/450092/
https://eprints.soton.ac.uk/450092/
Publikováno v:
Angewandte Chemie. 131:14966-14991
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ccfee541441caaf56ce9c175ff3c1df6
https://doi.org/10.1002/ange.201814457
https://doi.org/10.1002/ange.201814457
Autor:
David E, Wheatley, Clement Q, Fontenelle, Ramakrishna, Kuppala, Robert, Szpera, Edward L, Briggs, Jean-Baptiste, Vendeville, Neil J, Wells, Mark E, Light, Bruno, Linclau
Publikováno v:
The Journal of organic chemistry. 86(11)
Protein-carbohydrate interactions are implicated in many biochemical/biological processes that are fundamental to life and to human health. Fluorinated carbohydrate analogues play an important role in the study of these interactions and find applicat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::de605cea69bd18ea52ed43c7397e7b94
https://pubmed.ncbi.nlm.nih.gov/34029099
https://pubmed.ncbi.nlm.nih.gov/34029099
Publikováno v:
Beilstein Journal of Organic Chemistry, Vol 13, Iss 1, Pp 2883-2887 (2017)
Beilstein Journal of Organic Chemistry
Beilstein Journal of Organic Chemistry
The diastereoselective synthesis of fluorinated building blocks that contain chiral fluorine substituents is of interest. Here we describe optimisation efforts in the synthesis of anti-2,3-difluorobutane-1,4-diol, as well as the synthesis of the corr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::49fd8b62f97dd4afa56d7fbe7337ac14
https://doaj.org/article/21161b8923cc4b34bd071368d7fbf1f9
https://doaj.org/article/21161b8923cc4b34bd071368d7fbf1f9
Autor:
David M. H. Ascough, Stephen C. Hyde, Robert S. Paton, Janis Veliks, Véronique Gouverneur, Robert Szpera
Aryl substituted 2,2,2-trifluorodiazoethanes undergo rhodium(II)-catalysed insertion reactions with tin hydrides affording the corresponding α-(trifluoromethyl)benzyl stannanes. This reactivity contrasts with that of diazo esters which predominantly
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::035208309212136750f9546385eb11f1
https://ora.ox.ac.uk/objects/uuid:6651cb0f-de92-4b1d-b0a7-2227a4f9e4cf
https://ora.ox.ac.uk/objects/uuid:6651cb0f-de92-4b1d-b0a7-2227a4f9e4cf
Publikováno v:
POLYMER
The interplay of the relative configuration of diastereomeric vicinal difluoride groups on the conformational properties of polyesters has been investigated and compared to their non-fluorinated and per-fluorinated counterparts. The incorporation of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14144f9523ba250c25e74a58f79b5664
https://biblio.ugent.be/publication/8605245/file/8605246
https://biblio.ugent.be/publication/8605245/file/8605246
Publikováno v:
Angewandte Chemie (International ed. in English). 58(42)
This Review summarizes the advances in fluorination via C(sp2)–H and C(sp3)–H activation. Transition metal catalyzed approaches championed by palladium have allowed the installation of a fluorine substituent at C(sp2) and C(sp3) sites exploiting
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6336e8a126f6ca6070519d7163e14ea3
https://pubmed.ncbi.nlm.nih.gov/30759327
https://pubmed.ncbi.nlm.nih.gov/30759327
Autor:
Lucy van Dijk, Stephen P. Fletcher, Holly A. P. Bunce, Owen A. Smith, Robert Szpera, Michael J. Tilby
Publikováno v:
Nature Reviews Chemistry. 2
The past few decades have seen tremendous progress in the synthesis and operation of molecular systems capable of controlled mechanical movement. Here, we review the use of molecular machines as catalysts for controlling chemical reactions. We highli
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fe9e4448f906d5c916f72f1a47539c33
https://doi.org/10.1038/s41570-018-0117
https://doi.org/10.1038/s41570-018-0117