Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Robert Stainforth"'
Considerations for application of benchmark dose modeling in radiation research: workshop highlights
Autor:
Vinita Chauhan, Jihang Yu, Ngoc Vuong, Lynne T. Haber, Andrew Williams, Scott S. Auerbach, Danielle Beaton, Yi Wang, Robert Stainforth, Ruth C. Wilkins, Edouard I. Azzam, Richard B. Richardson, Md Gulam Musawwir Khan, Ashok Jadhav, Julie J. Burtt, Julie Leblanc, Kristi Randhawa, Knut Erik Tollefsen, Carole L. Yauk
Publikováno v:
International Journal of Radiation Biology. :1-12
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0deb023d4f3f12e6da2900022494f1d2
https://doi.org/10.1080/09553002.2023.2181998
https://doi.org/10.1080/09553002.2023.2181998
Autor:
Robert Stainforth, Ngoc Vuong, Nadine Adam, Byron Kuo, Ruth C. Wilkins, Carole Yauk, Afshin Beheshti, Vinita Chauhan
Publikováno v:
International Journal of Radiation Biology. 98:1832-1844
Benchmark dose (BMD) modeling is a method commonly used in chemical toxicology to identify the point of departure (POD) from a dose-response curve linked to a health-related outcome. Recently, its application in the analysis of transcriptional data f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::92583fe7bb692fa088b2d701c142a7b5
https://doi.org/10.1080/09553002.2022.2110300
https://doi.org/10.1080/09553002.2022.2110300
Publikováno v:
Int J Radiat Biol
Purpose Adverse outcome pathways (AOPs) provide a modular framework for describing sequences of biological key events (KEs) and key event relationships (KERs) across levels of biological organization. Empirical evidence across KERs can support constr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d979e9ac745056b91b4acf685e01ad3
https://pubmed.ncbi.nlm.nih.gov/32909875
https://pubmed.ncbi.nlm.nih.gov/32909875
Autor:
Thomas J. Cahill, Sylvain V. Costes, Jack M. Miller, Robert Meller, Komal S. Rathi, Gary Hardiman, Afshin Beheshti, Vinita Chauhan, J. Tyson McDonald, Willian A. da Silveira, Robert Stainforth, Deanne Taylor
Publikováno v:
Cancers
Volume 12
Issue 2
McDonald, J T, Stainforth, R, Miller, J, Cahill, T, da Silveira, W A, Rathi, K S, Hardiman, G, Taylor, D, Costes, S V, Chauhan, V, Meller, R & Beheshti, A 2020, ' NASA GeneLab Platform Utilized for Biological Response to Space Radiation in Animal Models ', Cancers, vol. 12, no. 2, 381 . https://doi.org/10.3390/cancers12020381
Cancers, Vol 12, Iss 2, p 381 (2020)
Volume 12
Issue 2
McDonald, J T, Stainforth, R, Miller, J, Cahill, T, da Silveira, W A, Rathi, K S, Hardiman, G, Taylor, D, Costes, S V, Chauhan, V, Meller, R & Beheshti, A 2020, ' NASA GeneLab Platform Utilized for Biological Response to Space Radiation in Animal Models ', Cancers, vol. 12, no. 2, 381 . https://doi.org/10.3390/cancers12020381
Cancers, Vol 12, Iss 2, p 381 (2020)
Background: Ionizing radiation from galactic cosmic rays (GCR) is one of the major risk factors that will impact the health of astronauts on extended missions outside the protective effects of the Earth&rsquo
s magnetic field. The NASA GeneLab p
s magnetic field. The NASA GeneLab p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a6bd69f49170975ec15d53b27ff77ae6
Publikováno v:
International journal of radiation biology. 97(1)
Adverse outcome pathways (AOPs) describe how a measurable sequence of key events, beginning from a molecular initiator, can lead to an adverse outcome of relevance to risk assessment. An AOP is modular by design, comprised of four main components: (1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9fceba3d9231bf47d6887c30ed62544d
https://pubmed.ncbi.nlm.nih.gov/31846388
https://pubmed.ncbi.nlm.nih.gov/31846388