Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Robert Snoecks"'
Autor:
Graciella Andrei, Yosuke Demizu, Tokumi Maruyama, Christophe Pannecouque, Myriam Witvrouw, Jan Balzarini, Shigetada Kozai, Robert Snoecks, Erik De Clercq
Publikováno v:
Nucleosides, Nucleotides and Nucleic Acids. 26:1553-1558
Antiviral activity of 1,3-disubstituted uracil derivatives was evaluated against HIV-1 and HCMV. It appears that the nitrogen of the 1-cyanomethyl group is important for anti-HIV-1 activity, suggesting interaction with the amino acid residues of HIV-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3e76dfd6df77bc71cab0d5509383477
https://doi.org/10.1080/15257770701545424
https://doi.org/10.1080/15257770701545424
Autor:
Graciella Andrei, Myriam Witvrouw, Robert Snoecks, Tokumi Maruyama, Yosuke Demizu, Jan Balzarini, Shigetada Kozai, Christophe Pannecouque, Erik De Clercq
Publikováno v:
ChemInform. 39
Antiviral activity of 1,3-disubstituted uracil derivatives was evaluated against HIV-1 and HCMV. It appears that the nitrogen of the 1-cyanomethyl group is important for anti-HIV-1 activity, suggesting interaction with the amino acid residues of HIV-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::83a9ad03e338b411700346270ce004da
https://doi.org/10.1002/chin.200813255
https://doi.org/10.1002/chin.200813255
Autor:
Yosuke Demizu, Robert Snoecks, Graciella Andrei, Tokumi Maruyama, Myriam Witvrouw, Christophe Pannecouque, Jan Balzarini, Shigetada Kozai, Erik De Clercq
Publikováno v:
ChemInform. 37
3-(3,5-Dimethylbenzyl)uracil (3) was treated with alkyl halides in the presence of alkali to give 1-substituted congeners. Condensation of 3 with alcohols using the Mitsunobu reaction was also employed as an alternative method. The anti-HIV-1 activit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::96fd0b4884acbde6225f21e1a2af84b1
https://doi.org/10.1002/chin.200634151
https://doi.org/10.1002/chin.200634151