Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Robert Silbajoris"'
Autor:
Phillip A. Wages, Robert Silbajoris, Adam Speen, Luisa Brighton, Andres Henriquez, Haiyan Tong, Philip A. Bromberg, Steven O. Simmons, James M. Samet
Publikováno v:
Redox Biology, Vol 3, Iss C, Pp 47-55 (2014)
Human exposure to particulate matter (PM) is a global environmental health concern. Zinc (Zn2+) is a ubiquitous respiratory toxicant that has been associated with PM health effects. However, the molecular mechanism of Zn2+ toxicity is not fully under
Externí odkaz:
https://doaj.org/article/5267f6d5c3674fb59fe29b71a7d8fcbe
Autor:
Philip A. Bromberg, James M. Samet, Huan-Cheng Chang, Nicholas Nunn, William P. Linak, Robert Silbajoris, Christopher K. Winterrowd, Olga Shenderova, Jay L. Zweier, Lisa A. Dailey, Anirudh Kota
Publikováno v:
Diamond and Related Materials. 58:16-23
Detonation nanodiamonds (DNDs), a nanomaterial with an increasing range of industrial and biomedical applications, have previously been shown to induce a pro-inflammatory response in cultured human airway epithelial cells (HAECs). We now show that su
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2e93e5bc8421738ee252910cece79335
https://doi.org/10.1016/j.diamond.2015.05.007
https://doi.org/10.1016/j.diamond.2015.05.007
Autor:
Robert Silbajoris, James M. Samet, Luisa E. Brighton, Haiyan Tong, Andres R. Henriquez, Steven O. Simmons, Adam M. Speen, Phillip A. Wages, Philip A. Bromberg
Publikováno v:
Redox Biology, Vol 3, Iss C, Pp 47-55 (2014)
Redox Biology
Redox Biology
Human exposure to particulate matter (PM) is a global environmental health concern. Zinc (Zn2+) is a ubiquitous respiratory toxicant that has been associated with PM health effects. However, the molecular mechanism of Zn2+ toxicity is not fully under
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a77e02be2b3f535758650edbaf3bccd8
http://www.sciencedirect.com/science/article/pii/S2213231714001116
http://www.sciencedirect.com/science/article/pii/S2213231714001116
Autor:
Seung-Hyun Cho, William P. Linak, Ram Ramabhadran, Robert Silbajoris, Tamara Tal, Lisa A. Dailey, Philip A. Bromberg, Steven O. Simmons, James M. Samet, William Reed
Publikováno v:
Toxicology and Applied Pharmacology. 243:46-54
Exposure to diesel exhaust particles (DEP) induces inflammatory signaling characterized by MAP kinase-mediated activation of NFkB and AP-1 in vitro and in bronchial biopsies obtained from human subjects exposed to DEP. NFkB and AP-1 activation result
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4653a7b163d8009a256f5b3d3a16a585
https://doi.org/10.1016/j.taap.2009.11.011
https://doi.org/10.1016/j.taap.2009.11.011
Autor:
Philip A. Bromberg, Jason Mingyi Huang, Robert Silbajoris, Ilona Jaspers, Wan-Yun Cheng, Lisa A. Dailey, Andrew J. Ghio, Tamara Tal, James M. Samet
Publikováno v:
Nanotoxicology. 3:152-160
Nanodiamond particles (NDP) prepared by detonational processes have a number of industrial and analytical applications. Previous in vitro studies have reported NDP to be biologically inert with negligible cytotoxicity, implying that they are potentia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::933fde966bcfb3f9bc80b0343763983d
https://doi.org/10.1080/17435390902725948
https://doi.org/10.1080/17435390902725948
Publikováno v:
Toxicology and Applied Pharmacology. 214:16-23
Epidemiological studies have implicated zinc (Zn2+) in the toxicity of ambient particulate matter (PM) inhalation. We previously showed that exposure to metal-laden PM inhibits protein tyrosine phosphatase (PTP) activity in human primary bronchial ep
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::184f211ffe590a825e0eded2cf045c17
https://doi.org/10.1016/j.taap.2005.11.011
https://doi.org/10.1016/j.taap.2005.11.011
Publikováno v:
European Respiratory Journal. 24:238-246
Lung overstretch involves mechanical factors, including large tidal volumes (VT), which induce inflammatory responses. The current authors hypothesised that inspiratory flow contributes to ventilator-induced inflammation. Buffer-perfused rabbit lungs
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e442969f060edfa297e96d287f0e1b4
https://doi.org/10.1183/09031936.04.00128703
https://doi.org/10.1183/09031936.04.00128703
Autor:
Dean Sheppard, Robert Silbajoris, Philip A. Bromberg, Weidong Wu, Lisa A. Dailey, James M. Samet, Lee M. Graves
Publikováno v:
American Journal of Respiratory Cell and Molecular Biology. 30:540-547
We have previously shown that exposure to zinc ions can activate epidermal growth factor (EGF) receptor (EGFR) signaling in murine fibroblasts and A431 cells through a mechanism involving Src kinase. While studying the effects of zinc ions in normal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f96a61fc42f67832e6a7d004b094f102
https://doi.org/10.1165/rcmb.2003-0233oc
https://doi.org/10.1165/rcmb.2003-0233oc
Autor:
Funmei Yang, Robert Silbajoris, Michael D. Garrick, Claude A. Piantadosi, Xinchao Wang, Andrew J. Ghio
Publikováno v:
American Journal of Physiology-Lung Cellular and Molecular Physiology. 284:L938-L944
Despite a lack of transferrin, hypotransferrinemic (Hp) mice demonstrate an accumulation of iron in peripheral organs including the lungs. One potential candidate for such transferrin-independent uptake of iron is divalent metal transporter-1 (DMT1),
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::61b03b999ef11ad5b49ad917fb692ecc
https://doi.org/10.1152/ajplung.00225.2002
https://doi.org/10.1152/ajplung.00225.2002
Publikováno v:
Environmental Health Perspectives
Metallic constituents contained in ambient particulate matter have been associated with adverse effects in a number of epidemiologic, in vitro, and in vivo studies. Residual oil fly ash (ROFA) is a metallic by-product of the combustion of fossil fuel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b0512fe366a41081eba0581fa425ce0
https://doi.org/10.1289/ehp.02110985
https://doi.org/10.1289/ehp.02110985