Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Robert Schmalzigaug"'
Autor:
Amanda C Martyn, Krisztian Toth, Robert Schmalzigaug, Nathan G Hedrick, Ramona M Rodriguiz, Ryohei Yasuda, William C Wetsel, Richard T Premont
Publikováno v:
PLoS ONE, Vol 13, Iss 3, p e0194350 (2018)
The signaling scaffold protein GIT1 is expressed widely throughout the brain, but its function in vivo remains elusive. Mice lacking GIT1 have been proposed as a model for attention deficit-hyperactivity disorder, due to alterations in basal locomoto
Externí odkaz:
https://doaj.org/article/40a0aacba1ec4d478275acafdc3fda0d
Microcephaly with altered cortical layering in GIT1 deficiency revealed by quantitative neuroimaging
Autor:
G. Allan Johnson, Woojoo Kim, Gary P. Cofer, Alexandra Badea, Cristian T. Badea, Robert Schmalzigaug, Richard T. Premont, Umer Ahmed, Pamela E. Bonner, Mark Foster, Robert J. Anderson
Publikováno v:
Magn Reson Imaging
G Protein-Coupled Receptor Kinase-Interacting Protein-1 (GIT1) regulates neuronal functions, including cell and axon migration and synapse formation and maintenance, and GIT1 knockout (KO) mice exhibit learning and memory deficits. We noted that male
Autor:
Richard T. Premont, Bastrikova N, Robert Schmalzigaug, William C. Wetsel, Ahmed U, Kim W, Ramona M. Rodriguiz, Krisztián Tóth, Amanda C. Martyn, Serena M. Dudek
G protein-coupled receptor kinase-interacting protein 2 (GIT2) and GIT1 are highly similar, sharing the same domain structure and many binding partners. The most important GIT partners are the p21-activated protein kinase-interacting exchange factor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f23e77a8b58c81d889fd4864f076b2d6
https://doi.org/10.1101/538223
https://doi.org/10.1101/538223
Autor:
Huanyao Gao, Richard T. Premont, Manish K. Singh, Zhiquan Song, Robert Schmalzigaug, Qisheng Zhang, Wei Sun
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 25:4838-4842
Both the Wnt/β-catenin signaling pathway and small GTPases of the ADP-ribosylation factors (ARF) family play important roles in regulating cell development, homeostasis and fate. The previous report of QS11, a small molecule Wnt synergist that binds
Autor:
Manikandan Paramasivam, Richard T. Premont, Sung-Soo Park, Huan Cai, Daoyuan Lu, Michael M. Seidman, Arya Biragyn, Robert Schmalzigaug, Bronwen Martin, Ionoa Bodogai, Sana Siddiqui, Stuart Maudsley, Caitlin M. Daimon
Publikováno v:
Molecular and cellular biology
Insults to nuclear DNA induce multiple response pathways to mitigate the deleterious effects of damage and mediate effective DNA repair. G-protein-coupled receptor kinase-interacting protein 2 (GIT2) regulates receptor internalization, focal adhesion
Autor:
Robert Schmalzigaug, Ryohei Yasuda, Richard T. Premont, Amanda C. Martyn, William C. Wetsel, Krisztián Tóth, Nathan G. Hedrick, Ramona M. Rodriguiz
Publikováno v:
PLoS ONE
PLoS ONE, Vol 13, Iss 3, p e0194350 (2018)
PLoS ONE, Vol 13, Iss 3, p e0194350 (2018)
The signaling scaffold protein GIT1 is expressed widely throughout the brain, but its function in vivo remains elusive. Mice lacking GIT1 have been proposed as a model for attention deficit-hyperactivity disorder, due to alterations in basal locomoto
Autor:
Manikandan Paramasivam, Sung-Soo Park, Richard T. Premont, Ionoa Bodogai, Caitlin M. Daimon, Robert Schmalzigaug, Michael M. Seidman, Stuart Maudsley, Sana Siddiqui, Huan Cai, Daoyuan Lu, Bronwen Martin, Arya Biragyn
Publikováno v:
Molecular and cellular biology. 37(17)
Insults to nuclear DNA induce multiple response pathways to mitigate the deleterious effects of damage and mediate effective DNA repair. G-protein-coupled receptor kinase-interacting protein 2 (GIT2) regulates receptor internalization, focal adhesion
Publikováno v:
Journal of Histochemistry & Cytochemistry. 55:1039-1048
SUMMARY GIT1 and GIT2 belong to the family of ADP-ribosylation factor GTPase-activating proteins (ARF-GAP) and have been implicated in the regulation of G protein-coupled receptor sequestration, cell migration, T-cell activation, neuronal spine forma
Autor:
Robert Schmalzigaug, Yanghui Xing, Marie-Line Garron, Stefan T. Arold, J. Tyler Roseman, Collin E. Davidson, Richard T. Premont
Publikováno v:
Cellular Signalling. 19:1733-1744
The GIT proteins, GIT1 and GIT2, are GTPase-activating proteins for the ADP-ribosylation factor family of small GTP-binding proteins, but also serve as adaptors to link signaling proteins to distinct cellular locations. One role for GIT proteins is t
Publikováno v:
Immunology. 103:332-342
Calmodulin (CaM) is the main intracellular Ca2+ sensor protein responsible for mediating Ca2+ triggered processes. Chicken DT40 lymphoma B cells express CaM from the two genes, CaMI and CaMII. Here we report the phenotypes of DT40 cells with the CaMI