Zobrazeno 1 - 10
of 79
pro vyhledávání: '"Robert S. Sloviter"'
Autor:
Raafat P Fares, Amor Belmeguenai, Pascal E Sanchez, Hayet Y Kouchi, Jacques Bodennec, Anne Morales, Béatrice Georges, Chantal Bonnet, Sandrine Bouvard, Robert S Sloviter, Laurent Bezin
Publikováno v:
PLoS ONE, Vol 8, Iss 1, p e53888 (2013)
Environmental enrichment of laboratory animals influences brain plasticity, stimulates neurogenesis, increases neurotrophic factor expression, and protects against the effects of brain insult. However, these positive effects are not constantly observ
Externí odkaz:
https://doaj.org/article/1dedcdb77bc14201b83f9e1a917e1cf2
Autor:
Robert S Sloviter, Terje eLømo
Publikováno v:
Frontiers in Neural Circuits, Vol 6 (2012)
In 1971, Andersen and colleagues proposed that excitatory activity in the entorhinal cortex propagates topographically to the dentate gyrus, and on through a trisynaptic circuit lying within transverse hippocampal slices or lamellae [Andersen, Bliss,
Externí odkaz:
https://doaj.org/article/2129537a559b4efb9b316b424d04251f
Autor:
Robert S. Sloviter
Publikováno v:
Current Opinion in Pharmacology. 35:105-110
Pharmacological treatment to prevent brain injury-induced temporal lobe epileptogenesis has been generally unsuccessful, raising the issues of exactly when the conversion process to an epileptic brain state occurs and reaches completion, and which ce
Publikováno v:
Epilepsia. 60
Cryptogenic temporal lobe epilepsy develops in the absence of identified brain injuries, infections, or structural malformations, and in these cases, an unidentified pre-existing abnormality may initiate febrile seizures, hippocampal sclerosis, and e
Publikováno v:
Epilepsia. 59(11)
Objective To determine when spontaneous granule cell epileptiform discharges first occur after hippocampal injury, and to identify the postinjury "latent" period as either a "silent" gestational state of epileptogenesis or a subtle epileptic state in
Autor:
Robert S. Sloviter, Morris Benveniste, Edyta K. Bichler, Matthew Smith, Ezekiel Carpenter-Hyland
Publikováno v:
Physiological Reports
Hippocampal neuron plasticity is strongly associated with learning, memory, and cognition. In addition to modification of synaptic function and connectivity, the capacity of hippocampal neurons to undergo plasticity involves the ability to change non
Autor:
Avtar Roopra, Claude G. Wasterlain, Michael A. Rogawski, Wytse J. Wadman, Douglas A. Coulter, Nadia Lelutiu, Pate Skene, Brita Fritsch, J. Victor Nadler, Yu Wang, Jan A. Gorter, James O. McNamara, Raymond Dingledine, Robert S. Sloviter, Asla Pitkänen
Publikováno v:
Scientific data, vol 4, iss 1
Scientific Data, 4:170061. Nature Publishing Group
Scientific Data, 4:170061. Nature Publishing Group
Global expression profiling of neurologic or psychiatric disorders has been confounded by variability among laboratories, animal models, tissues sampled, and experimental platforms, with the result being that few genes demonstrate consistent expressi
Publikováno v:
Neuropharmacology. 69:3-15
The "latent period" between brain injury and clinical epilepsy is widely regarded to be a seizure-free, pre-epileptic state during which a time-consuming cascade of molecular events and structural changes gradually mediates the process of "epileptoge
Autor:
Robert S. Sloviter, Braxton A. Norwood, Sven Wegner, Wolfgang H. Oertel, Hajo M. Hamer, Felix Rosenow, Sebastian Bauer
Publikováno v:
Epilepsia. 52:e109-e112
SUMMARY Perforant pathway stimulation (PPS) is used to study temporal lobe epilepsy in rodents. High-frequency PPS induces acute seizures, which can lead to neuron death and spontaneous epilepsy. However, the minimum duration of PPS that induces neur
Publikováno v:
The Journal of Comparative Neurology. 515:181-196
Prolonged dentate granule cell discharges produce hippocampal injury and chronic epilepsy in rats. In preparing to study this epileptogenic process in genetically altered mice, we determined whether the background strain used to generate most genetic