Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Robert S. Robison"'
Autor:
Jeffrey M. Howell, Amit Banerjee, Ramesh N. Patel, Laszlo J. Szarka, Robert S. Robison, Clyde G. McNamee
Publikováno v:
Enzyme and Microbial Technology. 14:731-738
A key chiral intermediate S (−)-4-chloro-3-hydroxybutanoic acid, methyl ester 2 was made in high optical purity by the stereoselective reduction of 4-chloro-3-oxobutanoic acid methyl ester 1 by cell suspensions of Geotrichum candidum SC 5469. A rea
Autor:
Robert S. Robison, John Kloss, Ramesh N. Patel, John K. Thottathil, Richard H. Mueller, Laszo J. Szarka
Publikováno v:
Enzyme and microbial technology. 13(11)
A key intermediate, (3R-cis)-1,3,4,5-tetrahydro-3-hydroxy-4-(4-methoxyphenyl)-6-(trifluorome thyl)- 2H-1-benzazepin-2-one (compound II or SQ32191), with high optical purity was made by the stereoselective microbial reduction of the parent ketone 1. S
Publikováno v:
Applied Microbiology and Biotechnology. 34
A key intermediate (S(−) 2-cyclohexyl-1,3-propanediol monoacetate) was made with high optical purity for the total synthesis of a new angiotensin converting enzyme inhibitor, Fosinopril. The stereoselective hydrolysis of 2-cyclohexyl-1,3-propanedio
Publikováno v:
Biochimica et Biophysica Acta. 77:73-86
A keratinolytic enzyme secreted by Streptomyces fradiae is shown to have the property of solubilizing more than one-third the weight of unaltered wool. As elaborated by the organism, the protease is conjugated to an acidic polymer; this form of the e
Autor:
Robert S. Robison
Publikováno v:
Soil Science Society of America Journal. 10:206-210
Publikováno v:
The Journal of Antibiotics. 21:611-615
Trienine, a new antitumor antibiotic, was isolated from the fermentation broth of Streptomyces SC3725. The substance, which contains three conjugated double bonds in a molecule weighing approximately 1, 400, is active in vitro against gram-positive b
Autor:
Henry R. Roberts, Robert S. Robison
Publikováno v:
Nature. 194
THE Δ1 dehydrogenation of 12α-fluoro,llβ-hydroxytestosterone by C. simplex is an extremely fast reaction. Peak conversion to product may occur within 1 hr. after addition of the substrate. Furthermore, the product is quickly degraded after the rea