Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Robert S. Rew"'
Publikováno v:
Experimental Parasitology. 55:159-167
Short-term (1-3 hr) incubations in vitro of immature and adult Fasciola hepatica with 10(-4) to 10(-5) M free amine of diamfenetide (DPT-FA) demonstrated a time/dose-dependent, irreversible paralysis that involved an increase in muscular tension and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b68857dd21db144d9f0aff50bea9abc
https://doi.org/10.1016/0014-4894(83)90010-3
https://doi.org/10.1016/0014-4894(83)90010-3
Autor:
Robert S. Rew, Howard J. Saz
Publikováno v:
The Journal of Cell Biology
Mitochondria from the muscle of the parasitic nematode Ascaris lumbricoides var. suum function anaerobically in electron transport-associated phosphorylations under physiological conditions. These helminth organelles have been fractionated into inner
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75bb67b0fd2b9fab41b3ea8934bc6202
http://europepmc.org/articles/PMC2109336
http://europepmc.org/articles/PMC2109336
Autor:
Robert S. Rew, R. H. Fetterer
Publikováno v:
Journal of Veterinary Pharmacology and Therapeutics. 7:113-118
Adult Fasciola hepatica recovered from sheep 12 and 24 h after a single oral dose of albendazole (20 mg/kg) contained significant amounts of two oxidized metabolites of albendazole (ABZ), a sulphoxide (SX) and a sulphone (SO), but not ABZ. Flukes inc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::652998433aff44b22806e8872ebe0fa4
https://doi.org/10.1111/j.1365-2885.1984.tb00886.x
https://doi.org/10.1111/j.1365-2885.1984.tb00886.x
Publikováno v:
Experimental Parasitology. 55:179-187
Larval stages of Oesophagostomum radiatum grown in vitro and adults grown in vivo were incubated in complex media or in a simple salt solution containing radioactive glucose. Glucose disappearance and end product accumulation of third-stage larvae in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d37c5dd894c875570e2c172fdc007af
https://doi.org/10.1016/0014-4894(83)90012-7
https://doi.org/10.1016/0014-4894(83)90012-7
Autor:
Robert S. Rew
Publikováno v:
Journal of Veterinary Pharmacology and Therapeutics. 1:183-197
The primary physiological mode of action of nearly all drugs used to control helminth parasites is not well understood. Examination of the general modes of action in terms of parasite requirements for survival may, however, provide guidelines to cont
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bb7a70cfd294d62890cfaf95fb2d4bce
https://doi.org/10.1111/j.1365-2885.1978.tb00326.x
https://doi.org/10.1111/j.1365-2885.1978.tb00326.x
Autor:
Robert S. Rew
Publikováno v:
Chemotherapy of Parasitic Diseases ISBN: 9781468412352
Human sleeping sickness is caused by one of two subspecies of Trypanosoma brucei: T. b. gambiense the causative agent of Gambian sleeping sickness and T. b. rhodesiense the causative agent of Rhodesian sleeping sickness. Gambian sleeping sickness is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3538d7907e0499373a42d579f6737562
https://doi.org/10.1007/978-1-4684-1233-8_5
https://doi.org/10.1007/978-1-4684-1233-8_5
Autor:
Robert S. Rew
Publikováno v:
Comparative Biochemistry of Parasitic Helminths ISBN: 9789401068611
There are times when in vitro efficacy is not translated into in vivo activity and vice versa. In very few instances have these lack of correlations been adequately explained, yet pharmaceutical house files are filled with candidate compounds which d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b216b96cac39da6bdb908e8efd681b59
https://doi.org/10.1007/978-94-009-0833-8_10
https://doi.org/10.1007/978-94-009-0833-8_10
Autor:
William C. Campbell, Robert S. Rew
Publikováno v:
Chemotherapy of Parasitic Diseases
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a63a72873ab628945e2eea20051e2dc1
https://doi.org/10.1007/978-1-4684-1233-8
https://doi.org/10.1007/978-1-4684-1233-8
Autor:
R. H. Fetterer, Robert S. Rew
Publikováno v:
Chemotherapy of Parasitic Diseases ISBN: 9781468412352
The purpose of this chapter is to describe biochemical or physiological events observed in nematodes exposed to an anthelmintic. Whether these pharmacologically mediated events truly represent a mode of action is difficult to prove, and the action de
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::82be81aa4d4f72af22025615036d7e46
https://doi.org/10.1007/978-1-4684-1233-8_16
https://doi.org/10.1007/978-1-4684-1233-8_16
Publikováno v:
Veterinary parasitology. 11(4)
Calves were given albendazole (ABZ) daily in feed at levels of 0,3 or 5 mg kg-1 day-1. None of the ABZ treatment levels was significantly effective in reducing Fasciola hepatica burdens. A dose rate of 5 mg kd-1 day-1 did significantly reduce the fec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::510753af8d5442dc1dca2806442c6c75
https://pubmed.ncbi.nlm.nih.gov/6892175
https://pubmed.ncbi.nlm.nih.gov/6892175