Zobrazeno 1 - 10
of 48
pro vyhledávání: '"Robert S. Papay"'
Publikováno v:
Current Research in Pharmacology and Drug Discovery, Vol 5, Iss , Pp 100160- (2023)
α1-Adrenergic Receptors (ARs) regulate the sympathetic nervous system by the binding of norepinephrine (NE) and epinephrine (Epi) through different subtypes (α1A, α1B, α1D). α1A-AR activation is hypothesized to be memory forming and cognitive en
Externí odkaz:
https://doaj.org/article/18c9eff23abc4bf8ad501881a7cf8f6c
Publikováno v:
Current Research in Pharmacology and Drug Discovery, Vol 4, Iss , Pp 100142- (2023)
α1-Adrenergic Receptors (ARs) are G-protein Coupled Receptors (GPCRs) that regulate the sympathetic nervous system via the binding and activation of norepinephrine (NE) and epinephrine (Epi). α1-ARs control various aspects of neurotransmission, cog
Externí odkaz:
https://doaj.org/article/ed111377c7e54e59be19c295e0b2513b
Publikováno v:
Current research in pharmacology and drug discovery. 4
α
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::8def8f88f7bdb9656686b91d7e47447b
https://pubmed.ncbi.nlm.nih.gov/36544813
https://pubmed.ncbi.nlm.nih.gov/36544813
Autor:
Dianne M. Perez, Robert S. Papay
Publikováno v:
Journal of Receptors and Signal Transduction. 41:138-144
The role of catecholamine receptors in cardiac energy metabolism is unknown. α1-adrenergic receptors (α1-ARs) have been identified to play a role in whole body metabolism but its role in cardiac en...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0da6ef7cb62636d6d33a39e9dc7e50b1
https://doi.org/10.1080/10799893.2020.1799291
https://doi.org/10.1080/10799893.2020.1799291
Autor:
Sathyamangla V. Naga Prasad, Robert S. Papay, Yu Sun, Conner P Witherow, Kate Stenson, Maradumane L. Mohan
Publikováno v:
Circulation Research. 129
Genetic deletion of Phosphoinositide 3-kinase (PI3Kγ) in mice (PI3Kγ -/- ) results in increased cAMP levels and enhanced ventricular rate/contractility. We investigated whether PI3Kγ plays a role in cardiac contractility by altering intracellular
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9d030f4d20d7675b0d775b0928b53f56
https://doi.org/10.1161/res.129.suppl_1.mp236
https://doi.org/10.1161/res.129.suppl_1.mp236
Autor:
Robert S, Papay, Dianne M, Perez
Publikováno v:
J Recept Signal Transduct Res
The role of catecholamine receptors in cardiac energy metabolism is unknown. α(1)-adrenergic receptors (α(1)-ARs) have been identified to play a role in whole body metabolism but its role in cardiac energy metabolism has not been explored. We used
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b4791905e7aa37216dcdba6dd34a8e0e
https://pubmed.ncbi.nlm.nih.gov/32757689
https://pubmed.ncbi.nlm.nih.gov/32757689
Publikováno v:
Circulation Research. 127
Genetic deletion of Phosphoinositide 3-kinase (PI3Kγ) in mice (PI3Kγ -/- ) results in increased cAMP levels and enhanced ventricular contractility. We investigated whether the lack of PI3Kγ plays a role in cardiac contractility by altering intrace
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::21b74ff86cc30ff1aef10f0493aed5aa
https://doi.org/10.1161/res.127.suppl_1.mp135
https://doi.org/10.1161/res.127.suppl_1.mp135
Autor:
Anita Sahu, Mitchell A. Olman, Maradumane L. Mohan, Lisa M. Grove, Robert S. Papay, Sathyamangla V. Naga Prasad
Publikováno v:
Circulation Research. 125
Phosphoinositide 3 Kinase γ (PI3Kγ) is an anti-apoptotic molecule acting through Akt pathway. Even though, role of PI3Kγ in cardiac fibrosis has been established, the mechanistic details by which PI3Kγ regulates cardiac myofibroblast differentiat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b7a27a15b79c52dd523b98704348ec7f
https://doi.org/10.1161/res.125.suppl_1.254
https://doi.org/10.1161/res.125.suppl_1.254
Publikováno v:
Journal of Receptors and Signal Transduction. 37:124-132
The role of α1-adrenergic receptors (α1-ARs) and their subtypes in metabolism is not well known. Most previous studies were performed before the advent of transgenic mouse models and utilized transformed cell lines and poorly selective antagonists.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fa6e213caa051d51d7dba583cc2101d6
https://doi.org/10.1080/10799893.2016.1193522
https://doi.org/10.1080/10799893.2016.1193522
Autor:
Lisa M. Grove, Mitchell A. Olman, Maradumane L. Mohan, Robert S. Papay, Sathyamangla V. Naga Prasad
Publikováno v:
Circulation Research. 123
Phosphoinositide 3 Kinase γ (PI3Kγ) regulates anti-apoptotic Akt signaling. Previous studies have established a role for PI3Kγ in cardiac fibrosis, a key underlying cause of heart failure. However, less is known about the mechanism by which PI3Kγ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d363a1925efcedd6d6ebd0547fa152dc
https://doi.org/10.1161/res.123.suppl_1.528
https://doi.org/10.1161/res.123.suppl_1.528