Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Robert S. Negm"'
Publikováno v:
Trends in Molecular Medicine. 8:288-293
Despite the recent decline in the incidence of cancer, long-term mortality rates remain unchanged. One of the most important factors in the survival of cancer is detection at an early stage. Clinical assays that detect the early events of cancer offe
Autor:
Robert T. Woodland, Robert S. Negm, Laura A. Solt, William D. Hastings, Thomas L. Rothstein, Thomas J. Schneider, Joseph R. Tumang, Thomas P. Colarusso
Publikováno v:
The Journal of Immunology. 168:2712-2719
B cell susceptibility to Fas-mediated apoptosis is regulated in a receptor-specific fashion. CD40 engagement produces marked sensitivity to Fas killing, whereas surface Ig (sIg) engagement blocks Fas signaling for cell death in otherwise sensitive, C
Autor:
Thomas L. Rothstein, Robert S. Negm, Xuemei Zhong, Macarena Irigoyen, Thomas J. Schneider, Takuya Mizuno
Publikováno v:
Molecular Immunology. 38:861-866
B cells stimulated by the combination of CD40L plus anti-Ig were screened for upregulated gene expression in an unbiased fashion through differential display. An inducible transcript was obtained that corresponds to a sequence previously isolated fro
Autor:
D. S. Cabral, Xuemei Zhong, Linda C. Foote, Robert S. Negm, Brian R. Schram, Terrence J. Donohoe, Thomas L. Rothstein, Thomas J. Schneider
Publikováno v:
Immunological Reviews. 176:116-133
The susceptibility of primary B cells to Fas (APO-1, CD95)-mediated apoptosis is modulated by signals derived from additional surface receptors: CD40 engagement produces upregulation of Fas expression and marked sensitivity to Fas-induced cell death,
Autor:
Thomas G. Pistole, Robert S Negm
Publikováno v:
Canadian Journal of Microbiology. 45:658-669
Macrophages recognize, adhere to, and phagocytose Salmonella typhimurium. The major outer membrane protein OmpC is a candidate ligand for macrophage recognition. To confirm this we used transposon mutagenesis to develop an ompC-deficient mutant in a
Autor:
Robert S. Negm, Thomas G. Pistole
Publikováno v:
Canadian Journal of Microbiology. 45:658-669
Autor:
Thomas G. Pistole, Robert S Negm
Publikováno v:
FEMS immunology and medical microbiology. 20(3)
Murine peritoneal macrophages bind to Salmonella typhimurium in vitro in the absence of exogenous opsonins. We have identified an outer membrane protein of S. typhimurium that mediates this adhesion. Biotin-labeled macrophages were used to probe elec