Zobrazeno 1 - 10
of 163
pro vyhledávání: '"Robert S. McCuskey"'
Autor:
Alessandra Warren, Victoria C. Cogger, Robin Fraser, Laurie D. DeLeve, Robert S. McCuskey, David G. Le Couteur
Publikováno v:
Current Gerontology and Geriatrics Research, Vol 2011 (2011)
Aging is associated with marked changes in the hepatic sinusoid, yet the effect of old age on hepatic stellate cells (HSC) has not been well described. Transmission electron microscopy and immunohistochemistry were used to study the effects of aging
Externí odkaz:
https://doaj.org/article/80a7c13c5fbe4e048ec335e15a910ee3
Publikováno v:
Comprehensive Toxicology
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::922b743ac25e9e11ba16d401e79c5c78
https://doi.org/10.1016/b978-0-12-801238-3.95659-9
https://doi.org/10.1016/b978-0-12-801238-3.95659-9
Publikováno v:
Comprehensive Physiology
The liver sinusoidal endothelial cell (LSEC) forms the fenestrated wall of the hepatic sinusoid and functions as a control post regulating and surveying the trafficking of molecules and cells between the liver parenchyma and the blood. The cell acts
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4154702212150bc5829a34b8645410cc
https://doi.org/10.1002/cphy.c140078
https://doi.org/10.1002/cphy.c140078
Autor:
Narcissus Teoh, Derrick M. Van Rooyen, Mark E. Koina, Lay T. Gan, Robert S. McCuskey, Geoffrey C. Farrell
Publikováno v:
Journal of Hepatology. 61:1376-1384
Free cholesterol (FC) accumulates in non-alcoholic steatohepatitis (NASH) but not in simple steatosis. We sought to establish how FC causes hepatocyte injury.In NASH-affected livers from diabetic mice, subcellular FC distribution (filipin fluorescenc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01ce9f3b596e0f607bcc96101bf860ae
https://doi.org/10.1016/j.jhep.2014.07.024
https://doi.org/10.1016/j.jhep.2014.07.024
Autor:
Peter McCourt, Svetlana N. Zykova, Karen Kristine Sørensen, Bård Smedsrød, Andrew J. McLachlan, Ana Oteiza, Dmitri Svistounov, Robert S. McCuskey
Publikováno v:
Experimental Gerontology. 48:549-556
Aging is characterized by progressive loss of metabolic and biochemical functions and accumulation of metabolic by-products, including advanced glycation end products (AGEs), which are observed in several pathological conditions. A number of waste ma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::45b585bdec20be9648bcba70b15d0036
https://doi.org/10.1016/j.exger.2013.03.005
https://doi.org/10.1016/j.exger.2013.03.005
Autor:
David G. Le Couteur, Robin Fraser, Robert S. McCuskey, Victoria C. Cogger, Alessandra Warren, Laurie D. DeLeve
Publikováno v:
Current Gerontology and Geriatrics Research
Current Gerontology and Geriatrics Research, Vol 2011 (2011)
Current Gerontology and Geriatrics Research, Vol 2011 (2011)
Aging is associated with marked changes in the hepatic sinusoid, yet the effect of old age on hepatic stellate cells (HSC) has not been well described. Transmission electron microscopy and immunohistochemistry were used to study the effects of aging
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a0ecbad6aa174a292ca02b46f28ef930
https://doi.org/10.1155/2011/439835
https://doi.org/10.1155/2011/439835
Autor:
Irwin M. Arias, Robert S. McCuskey, Victoria C. Cogger, Alessandra Warren, David G. Le Couteur
Publikováno v:
Microcirculation. 17:32-38
Microcirculation (2010) 17, 32–38. doi: 10.1111/j.1549-8719.2009.00004.x Abstract Objective: Fenestrations are pores in the liver sinusoidal endothelium that facilitate the transfer of particulate substrates between the sinusoidal lumen and hepatoc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99b6ea75cfceda8479768d5f4084ca0a
https://doi.org/10.1111/j.1549-8719.2009.00004.x
https://doi.org/10.1111/j.1549-8719.2009.00004.x
Autor:
Robert S. McCuskey, Marian L. Miller
Publikováno v:
Scandinavian Journal of Haematology. 10:17-23
The tibias of fetal, neonatal and mature New Zealand albino rabbits were investigated histochemically to elucidate the development of innervation of the blood vessels and parenchyma in the marrow cavity. The neurovascular complex in the marrow was de
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e3411a66f150f090c8c8618b0e056b6
https://doi.org/10.1111/j.1600-0609.1973.tb00033.x
https://doi.org/10.1111/j.1600-0609.1973.tb00033.x
Autor:
Niel C. Hoglen, Scott A. Mobley, Glenn Sipes, John Michael Sauer, R. Clark Lantz, David L. Earnest, Robert S. McCuskey, Edward A. Abril
Publikováno v:
Liver. 17:157-165
Previous studies have shown that large doses of vitamin A potentiate chemical-induced liver injury and that the Kupffer cell is directly involved in this potentiation. Therefore, these studies were designed to determine if Kupffer cells isolated from
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d8bb7e77b238bb2ff0f43b9b08419f9d
https://doi.org/10.1111/j.1600-0676.1997.tb00799.x
https://doi.org/10.1111/j.1600-0676.1997.tb00799.x
Publikováno v:
The Anatomical Record: Advances in Integrative Anatomy and Evolutionary Biology. 291:684-692
Nonalcoholic fatty liver disease (NAFLD), the most common cause of steatosis, is associated with visceral obesity and insulin resistance. With more severe risk factors (obesity, type 2 diabetes [T2D], metabolic syndrome), steatosis may be complicated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6332b21b5aa7681b1d396c3e4581dcd7
https://doi.org/10.1002/ar.20715
https://doi.org/10.1002/ar.20715