Zobrazeno 1 - 10
of 39
pro vyhledávání: '"Robert S. Goodwin"'
Autor:
Wendy M Bosker, Erin L Karschner, Dayong Lee, Robert S Goodwin, Jussi Hirvonen, Robert B Innis, Eef L Theunissen, Kim P C Kuypers, Marilyn A Huestis, Johannes G Ramaekers
Publikováno v:
PLoS ONE, Vol 8, Iss 1, p e53127 (2013)
The present study assessed psychomotor function in chronic, daily cannabis smokers during 3 weeks continuously monitored abstinence on a secure research unit. We hypothesized that psychomotor performance would improve during abstinence of chronic, da
Externí odkaz:
https://doaj.org/article/e5c24cdfb6ed4b8cbf760f9e300aa6be
Autor:
Madeleine J. Swortwood, Erin L. Karschner, Wendy M. Bosker, Marilyn A. Huestis, Johannes G. Ramaekers, Jussi Hirvonen, Robert S. Goodwin
Publikováno v:
Drug Testing and Analysis. 8:682-689
Cannabis smoking increases motor vehicle accident risk. Empirically defined cannabinoid detection windows are important to drugged driving legislation. Our aims were to establish plasma cannabinoid detection windows in frequent cannabis smokers and t
Autor:
Robert S. Goodwin, Dayong Lee, Jussi Hirvonen, David A. Gorelick, Erin L. Karschner, Jennifer R. Schroeder, Marilyn A. Huestis
Publikováno v:
The American Journal on Addictions. 23:234-242
Objectives: Chronic, frequent cannabis smokers may experience residual and offset effects, withdrawal, and craving when abstaining from the drug. We characterized the prevalence, duration, and intensity of these effects in chronic frequent cannabis s
Autor:
Karl B. Scheidweiler, Erin A. Kolbrich-Spargo, Marilyn A. Huestis, Keming Yun, Rebecca L. Hartman, Robert S. Goodwin, Nathalie A. Desrosiers, Allan J. Barnes, David A. Gorelick
Publikováno v:
Analytical and Bioanalytical Chemistry. 406:587-599
3,4-Methylenedioxymethamphetamine (MDMA) is an illicit phenethylamine ingested for entactogenic and euphoric effects. Although blood is more commonly submitted for forensic analysis, previous human MDMA pharmacokinetics research focused on plasma dat
Autor:
Deanna L. Kelly, Jennifer R. Schroeder, Denis Bonnet, Eugene W. Schwilke, Marilyn A. Huestis, Catherine Ortemann-Renon, David A. Gorelick, David M. Schwope, Robert S. Goodwin
Publikováno v:
The American Journal on Addictions. 22:510-514
Background and Objectives Δ9-tetrahydrocannabinol (THC) promotes sleep in animals; clinical use of THC is associated with somnolence. Human laboratory studies of oral THC have not shown consistent effects on sleep. We prospectively evaluated self-re
Autor:
Robert S. Goodwin, Garry Milman, Marilyn A. Huestis, Dayong Lee, Allan J. Barnes, Erin L. Karschner
Publikováno v:
Drug and Alcohol Dependence. 130:68-76
a b s t r a c t Objectives: We characterize cannabinoid disposition in oral fluid (OF) after dronabinol, synthetic oral � 9 - tetrahydrocannabinol (THC), and Sativex, a cannabis-extract oromucosal spray, and evaluate whether smoked cannabis relapse
Autor:
Allan J. Barnes, Marilyn A. Huestis, Erin A. Kolbrich-Spargo, Robert S. Goodwin, David A. Gorelick, Karl B. Scheidweiler, Rebecca L. Hartman, Nathalie A. Desrosiers
Publikováno v:
Analytical and Bioanalytical Chemistry. 405:4067-4076
Oral fluid (OF) offers a noninvasive sample collection for drug testing. However, 3,4-methylenedioxymethamphetamine (MDMA, ecstasy) in OF has not been adequately characterized in comparison to plasma. We administered oral low-dose (1.0 mg/kg) and hig
Autor:
Robert S. Goodwin, Jussi Hirvonen, Erin L. Karschner, Regina Helena Costa Queiroz, Marilyn A. Huestis, Karl B. Scheidweiler, Mateus M. Bergamaschi
Publikováno v:
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Universidade de São Paulo (USP)
instacron:USP
BACKGROUND Cannabis is the illicit drug most frequently reported with impaired driving and motor vehicle accidents. Some “per se” laws make it illegal to drive with any amount of drug in the body, while others establish blood, saliva, or urine co
Autor:
Eugene W. Schwilke, Marilyn A. Huestis, Deanna L. Kelly, David A. Gorelick, David M. Schwope, Erin L. Karschner, Robert S. Goodwin
Publikováno v:
Drug and Alcohol Dependence. 125:313-319
Determining time since last cannabis/Δ9-tetrahydrocannabinol (THC) exposure is important in clinical, workplace, and forensic settings. Mathematical models calculating time of last exposure from whole blood concentrations typically employ a theoreti
Autor:
Colleen Rock, Rolley E. Johnson, Diana G. Wilkins, Sarah K. Himes, Marilyn A. Huestis, Hendrée E. Jones, Robert S. Goodwin
Publikováno v:
Therapeutic Drug Monitoring. 34:337-344
Methadone is the recommended pharmacotherapy for opioid-dependent pregnant women. The primary aims of this study were to determine whether a dose-concentration relationship exists between cumulative maternal methadone dose, methadone and metabolite c