Zobrazeno 1 - 10
of 41
pro vyhledávání: '"Robert S. Balderas"'
Autor:
Banumathi Tamilselvan, Zachary Jackson, Susan Pereira Ribeiro, Jill S. Barnholtz-Sloan, Jaroslaw P. Maciejewski, David N. Wald, Kalpana Gupta, Ashish Sharma, Xuan Xu, Rafick-Pierre Sekaly, Robert Schauner, Anne Roe, Samuel Li, Robert S. Balderas, Tae Hyun Hwang, Lindsay Stetson, Slim Fourati, Marcos de Lima, Thomas LaFramboise, Dheepa Balasubramanian, Yogen Saunthararajah, Tammy Stefan
Publikováno v:
Leukemia
The prognosis of most patients with AML is poor due to frequent disease relapse. The cause of relapse is thought to be from the persistence of leukemia initiating cells (LIC's) following treatment. Here we assessed RNA based changes in LICs from matc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a5a602a1f29de6b5360b3e7daf3b3d7d
https://doi.org/10.1038/s41375-021-01338-7
https://doi.org/10.1038/s41375-021-01338-7
Autor:
Susan Pereira Ribeiro, Daniel Lamarre, Peter W. Hunt, Carey L. Shive, Andrey Loboda, Aarthi Talla, Jeffery Ahlers, Xuan Xu, Benigno Rodriguez, Deanna A. Kulpa, Razvan Cristescu, Khader Ghneim, Slim Fourati, Robert S. Balderas, Steven G. Deeks, Rafick Pierre Sekaly, I-Ming Wang, Ashish Sharma, Michael M. Lederman, Daria J. Hazuda, Jessica H. Brehm, Daniel C. Douek
Current therapeutic interventions to eradicate latent HIV (“reservoir”) and restore immune function in ART-treated HIV infection have yet to show efficacy. To explore mechanisms of HIV persistence, we apply an integrated systems biology approach
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a3b19b525a9f69b5f7c68117fcbf2b19
https://doi.org/10.21203/rs.3.rs-923015/v1
https://doi.org/10.21203/rs.3.rs-923015/v1
Autor:
Steven G. Deeks, Razvan Cristescu, Peter W. Hunt, Khader Ghneim, I-Ming Wang, Robert S. Balderas, Susan Pereira Ribeiro, Samuel Darko, Sahaana Arumugam, Ali Filali-Mouhim, Rafick-Pierre Sekaly, Daniel Lamarre, Aarthi Talla, Michael M. Lederman, Ashish Sharma, Xuan Xu, Benigno Rodriguez, Daniel C. Douek, Daria J. Hazuda, Jessica H. Brehm, Deanna A. Kulpa, Jeffery Ahlers, Carey L. Shive, Andrey Loboda, Slim Fourati
Publikováno v:
SSRN Electronic Journal.
Therapeutic interventions to eradicate latent HIV in ART-treated infection have yet to show efficacy. We used a systems biology approach to identify a subset of ART-treated individuals with immune-dysfunction that had the highest frequencies of cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::be86938b4d65c93bcb04d60eabdbcdb0
https://doi.org/10.2139/ssrn.3822732
https://doi.org/10.2139/ssrn.3822732
Autor:
Steven G. Deeks, Ashish Sharma, Jeffrey D. Ahlers, Xuan Xu, I-Ming Wang, Susan Pereira Ribeiro, Robert S. Balderas, Daria J. Hazuda, Sahaana Arumugam, Jessica H. Brehm, Slim Fourati, Daniel Lamarre, Peter W. Hunt, Rafick-Pierre Sekaly, Benigno Rodriguez, Carey L. Shive, Deanna A. Kulpa, Andrey Loboda, Samuel Darko, Aarthi Talla, Michael M. Lederman, Razvan Cristescu, Daniel C. Douek, Khader Ghneim
SummaryCurrent therapeutic interventions to eradicate latent HIV (“reservoir”) and restore immune function in ART-treated HIV infection have yet to show efficacy. To explore mechanisms of HIV persistence, we apply an integrated systems biology ap
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::715c4ad54f766f272222dd67fc1de346
https://doi.org/10.1101/2020.12.15.422949
https://doi.org/10.1101/2020.12.15.422949
Publikováno v:
PLoS ONE, Vol 6, Iss 4, p e19038 (2011)
Signaling events affecting thymic selection of un-manipulated polyclonal natural CD25(+)foxp3(+) regulatory T cells (nTreg) have not been established ex vivo. Here, we report a higher frequency of phosphorylated STAT-5 (pSTAT-5) in nTreg cells in the
Externí odkaz:
https://doaj.org/article/0ee26b5c1bb64925ae201424d7e118cd
Autor:
Virginia O. Volpe, Rafael Bejar, Rami S. Komrokji, Maria E. Balasis, Traci Kruer, Meghan C. Ferrall-Fairbanks, Philipp M. Altrock, Anthony M. Hunter, Hannah Newman, Eric Padron, Jodi Kroeger, David A. Sallman, Christopher Letson, Brian J. Johnson, Robert S. Balderas, Abhishek Dhawan
Publikováno v:
Blood. 138:319-319
Myeloblasts are associated with adverse outcomes and define transformation to acute myeloid leukemia in all chronic myeloid neoplasms. Myeloblasts represent hematopoietic stem and progenitor cells (HSPCs) that express CD34, but are never resolved int
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d512d0c7126d38e02ce0125931f6652c
https://doi.org/10.1182/blood-2021-151348
https://doi.org/10.1182/blood-2021-151348
Autor:
Peiqing Shi, Yoichiro Ohne, Capucine Picard, Priya Narayanan, Jean-Laurent Casanova, Jean-Pierre Gorvel, Sangkon Oh, Wei Xu, Ning Kang, Marie Cecile Herve, Robert S. Balderas, Sandra Clayton, Jacques Banchereau, Virginia Pascual
Publikováno v:
European Journal of Immunology. 44:275-284
While studying the plasma cell (PC) compartment in human tonsils, we identified that immunoglobulin kappa or lambda chain-expressing PCs are the main cells expressing granzyme B (GrzB). In vitro studies revealed that activated B cells differentiated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::101c2182f78790664e48b1d5aa963c5a
https://doi.org/10.1002/eji.201343711
https://doi.org/10.1002/eji.201343711
Autor:
Janice M. Moser, Rama Akondy, Elias A. Said, Bader Yassine-Diab, Rafick Pierre Sekaly, Aline Rinfret, Peter Wilkinson, Mark J. Cameron, Robert S. Balderas, Denis Gaucher, Nadia Kettaf, David J. Kelvin, Jim Tartaglia, Geneviève Boucher, Robert Clum, Elias K. Haddad, Bastian R. Angermann, Abdelali Filali-Mouhim, Giuseppe Pantaleo, René Therrien, Riyaz Mehta, Donald Drake, Roland Somogyi, Erika Castro, Larry D. Greller, Younes Chouikh
Publikováno v:
Journal of Experimental Medicine, vol. 205, no. 13, pp. 3119-3131
The Journal of Experimental Medicine
The Journal of Experimental Medicine
Correlates of immune-mediated protection to most viral and cancer vaccines are still unknown. This impedes the development of novel vaccines to incurable diseases such as HIV and cancer. In this study, we have used functional genomics and polychromat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::34dbe2aaa023407cc208320d2ccd99cc
https://doi.org/10.1084/jem.20082292
https://doi.org/10.1084/jem.20082292
Autor:
Julien van Grevenynghe, Mark J. Cameron, Robert S. Balderas, Yu Shi, Roberto Campos-Gonzalez, Peter Wilkinson, Catherine Riou, Larry D. Greller, Rafick-Pierre Sekaly, Bader Yassine-Diab, Elias K. Haddad, Roland Somogyi, David J. Kelvin, Dominic Gagnon, Sylvain Gimmig
Publikováno v:
The Journal of Experimental Medicine
The molecular events involved in the establishment and maintenance of CD4+ central memory and effector memory T cells (TCM and TEM, respectively) are poorly understood. In this study, we demonstrate that ex vivo isolated TCM are more resistant to bot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dcce46e73ed109dd8b9fd98b46370d1a
http://europepmc.org/articles/PMC2118424
http://europepmc.org/articles/PMC2118424
Autor:
Vaclav Horejsi, F. Mortari, Georgina J. Clark, Robert S. Balderas, Hannes Stockinger, Armand Bensussan, Fabio Malavasi, Reinhard Schwartz-Albiez, Heddy Zola, Laurence Boumsell, Pablo Engel, Valter Gattei, Menno C. van Zelm, Bo Quan Jin
CD (cluster of differentiation) Ags are cell surface molecules expressed on leukocytes and other cells relevant for the immune system. CD nomenclature has been universally adopted by the scientific community and is officially approved by the Internat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::58cfcbc76471261fe3ed9608e9d4410f
http://hdl.handle.net/2318/1573452
http://hdl.handle.net/2318/1573452