Zobrazeno 1 - 10
of 72
pro vyhledávání: '"Robert S Stephenson"'
Autor:
Theodora Nikolaidou, Xue J Cai, Robert S Stephenson, Joseph Yanni, Tristan Lowe, Andrew J Atkinson, Caroline B Jones, Rida Sardar, Antonio F Corno, Halina Dobrzynski, Philip J Withers, Jonathan C Jarvis, George Hart, Mark R Boyett
Publikováno v:
PLoS ONE, Vol 10, Iss 10, p e0141452 (2015)
Heart failure is a major killer worldwide. Atrioventricular conduction block is common in heart failure; it is associated with worse outcomes and can lead to syncope and bradycardic death. We examine the effect of heart failure on anatomical and ion
Externí odkaz:
https://doaj.org/article/d33c3f6f1d1b40f3a4dd15ab952a257b
Autor:
Robert S Stephenson, Mark R Boyett, George Hart, Theodora Nikolaidou, Xue Cai, Antonio F Corno, Nelson Alphonso, Nathan Jeffery, Jonathan C Jarvis
Publikováno v:
PLoS ONE, Vol 7, Iss 4, p e35299 (2012)
The general anatomy of the cardiac conduction system (CCS) has been known for 100 years, but its complex and irregular three-dimensional (3D) geometry is not so well understood. This is largely because the conducting tissue is not distinct from the s
Externí odkaz:
https://doaj.org/article/c912c3e77a0f44caba463f2d0f33bd96
Autor:
Sunil Jit R.J. Logantha, James O. Tellez, Mark R. Boyett, Eman S.H. Abd Allah, Cali Anderson, P. Mesirca, Natalie Chandler, Matthew K. Lancaster, Matteo E. Mangoni, Joseph Yanni, George Hart, Jonathan P. Ariyaratnam, Matthew Smith, Henggui Zhang, Robert S. Stephenson, Luke Stuart, Gwilym M. Morris, Claire Wilson, Xue Cai, Rudi Billeter, Alicia D'Souza, Annalisa Bucchi, Sandra C. Jones, Oliver J. Monfredi, Carol T. Bussey, Shu Nakao
Publikováno v:
Progress in Biophysics and Molecular Biology
Progress in Biophysics and Molecular Biology, Elsevier, 2021, 166, pp.61-85. ⟨10.1016/j.pbiomolbio.2021.06.008⟩
PROGRESS IN BIOPHYSICS & MOLECULAR BIOLOGY
Boyett, M, Yanni Gerges, J, Tellez, J O, Bucchi, A, Mesirca, P, Cai, X, Logantha, S J R J, Wilson, C, Anderson, C, Ariyaratnam, J, Stuart, L, Nakao, S, Allah, E A, Jones, S A, Lancaster, M, Stephenson, R S, Chandler, N, Smith, M, Bussey, C, Monfredi, O, Morris, G, Billeter, R, Mangoni, M E, Zhang, H, Hart, G & D'Souza, A 2021, ' Regulation of sinus node pacemaking and atrioventricular node conduction by HCN channels in health and disease ', Progress in biophysics and molecular biology, vol. 166, pp. 61-85 . https://doi.org/10.1016/j.pbiomolbio.2021.06.008
Progress in Biophysics and Molecular Biology, Elsevier, 2021, 166, pp.61-85. ⟨10.1016/j.pbiomolbio.2021.06.008⟩
PROGRESS IN BIOPHYSICS & MOLECULAR BIOLOGY
Boyett, M, Yanni Gerges, J, Tellez, J O, Bucchi, A, Mesirca, P, Cai, X, Logantha, S J R J, Wilson, C, Anderson, C, Ariyaratnam, J, Stuart, L, Nakao, S, Allah, E A, Jones, S A, Lancaster, M, Stephenson, R S, Chandler, N, Smith, M, Bussey, C, Monfredi, O, Morris, G, Billeter, R, Mangoni, M E, Zhang, H, Hart, G & D'Souza, A 2021, ' Regulation of sinus node pacemaking and atrioventricular node conduction by HCN channels in health and disease ', Progress in biophysics and molecular biology, vol. 166, pp. 61-85 . https://doi.org/10.1016/j.pbiomolbio.2021.06.008
The funny current, I f, was first recorded in the heart 40 or more years ago by Dario DiFrancesco and others. Since then, we have learnt that I f plays an important role in pacemaking in the sinus node, the innate pacemaker of the heart, and more rec
Autor:
Jakob Lindhardt, Nikolaj Bøgh, Robert S. Stephenson, Per Mose Nielsen, Peter Agger, Esben Søvsø Szocska Hansen, Camilla Omann, Vibeke E. Hjortdal, Christoffer Laustsen
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-9 (2020)
Scientific Reports
Bøgh, N, Søvsø Szocska Hansen, E, Omann, C, Lindhardt, J L, Nielsen, P M, Stephenson, R S, Laustsen, C, Hjortdal, V E & Agger, P 2020, ' Increasing carbohydrate oxidation improves contractile reserves and prevents hypertrophy in porcine right heart failure ', Scientific Reports, vol. 10, 8158 . https://doi.org/10.1038/s41598-020-65098-7
Scientific Reports
Bøgh, N, Søvsø Szocska Hansen, E, Omann, C, Lindhardt, J L, Nielsen, P M, Stephenson, R S, Laustsen, C, Hjortdal, V E & Agger, P 2020, ' Increasing carbohydrate oxidation improves contractile reserves and prevents hypertrophy in porcine right heart failure ', Scientific Reports, vol. 10, 8158 . https://doi.org/10.1038/s41598-020-65098-7
In heart failure, myocardial overload causes vast metabolic changes that impair cardiac energy production and contribute to deterioration of contractile function. However, metabolic therapy is not used in heart failure care. We aimed to investigate t
Autor:
Robert H. Anderson, Marios Loukas, Vera Demarchi Aiello, Marcos C. de Almeida, Luiz Alberto Benvenuti, Robert S. Stephenson
Publikováno v:
Heart Rhythm. 17:123-130
Background The right ventricular outflow tract is the most common source of ventricular arrhythmias in nonstructural heart disease. Most of these arrhythmias are of endocardial origin, but their morphologic substrate is mostly unknown. Objective The
Autor:
Sunil Jit R. J. Logantha, Joseph Yanni, Ashraf Kitmitto, Oliver J. Monfredi, Luke Stuart, Akbar Vohra, Shu Nakao, R Hutcheon, Tobias Starborg, Caroline Jones, GM Quigley, George Hart, Robert S. Stephenson, Jonathan C. Jarvis, X. Cai, Antonio F. Corno, Il Young Oh, Halina Dobrzynski, Mark R. Boyett
Publikováno v:
Circulation. Heart Failure
Logantha, S J R J, Cai, X J, Yanni, J, Jones, C B, Stephenson, R S, Stuart, L, Quigley, G, Monfredi, O, Nakao, S, Oh, I Y, Starborg, T, Kitmitto, A, Vohra, A, Hutcheon, R C, Corno, A F, Jarvis, J C, Dobrzynski, H, Boyett, M R & Hart, G 2021, ' Remodeling of the Purkinje Network in Congestive Heart Failure in the Rabbit ', Circulation. Heart Failure, vol. 14, no. 7, pp. 800-816 . https://doi.org/10.1161/CIRCHEARTFAILURE.120.007505
Logantha, S J R J, Cai, X J, Yanni, J, Jones, C B, Stephenson, R S, Stuart, L, Quigley, G, Monfredi, O, Nakao, S, Oh, I Y, Starborg, T, Kitmitto, A, Vohra, A, Hutcheon, R C, Corno, A F, Jarvis, J C, Dobrzynski, H, Boyett, M R & Hart, G 2021, ' Remodeling of the Purkinje Network in Congestive Heart Failure in the Rabbit ', Circulation. Heart Failure, vol. 14, no. 7, pp. 800-816 . https://doi.org/10.1161/CIRCHEARTFAILURE.120.007505
Supplemental Digital Content is available in the text.
Background: Purkinje fibers (PFs) control timing of ventricular conduction and play a key role in arrhythmogenesis in heart failure (HF) patients. We investigated the effects of HF on PFs. M
Background: Purkinje fibers (PFs) control timing of ventricular conduction and play a key role in arrhythmogenesis in heart failure (HF) patients. We investigated the effects of HF on PFs. M
Autor:
Robert H. Anderson, Damián Sánchez-Quintana, Peter F. Niederer, Peter Agger, Robert S. Stephenson
Publikováno v:
Anderson, R H, Niederer, P F, Sanchez-Quintana, D, Stephenson, R S & Agger, P 2019, ' How are the cardiomyocytes aggregated together within the walls of the left ventricular cone? ', Journal of Anatomy, vol. 235, no. 4, pp. 697-705 . https://doi.org/10.1111/joa.13027
J Anat
J Anat
The manner of packing together of the cardiomyocytes within the walls of the cardiac ventricles has now been investigated for over half a millennium. In 1669, Lower dissected the ventricular mass, likening the arrangement to skeletal musculature, in
Publikováno v:
BMJ Open, Vol 11, Iss 2 (2021)
BMJ Open
BMJ Open
IntroductionChronic spinal pain (CSP) is the most common musculoskeletal disorder and is a leading cause of disability as per the Global Burden of Diseases. Previous reviews of microscopic changes in the spinal extensor muscles of people with CSP hav
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce4383194ade8709b499a65be28284ce
https://e-space.mmu.ac.uk/627664/
https://e-space.mmu.ac.uk/627664/
Autor:
Robert S. Stephenson, Mark R. Boyett, George Hart, Theodora Nikolaidou, Xue Cai, Antonio F. Corno, Nelson Alphonso, Nathan Jeffery, Jonathan C. Jarvis
Publikováno v:
PLoS ONE, Vol 7, Iss 4 (2012)
Externí odkaz:
https://doaj.org/article/734bf6493fc94d07ad438b69ef31cf3b
Publikováno v:
Agger, P, Omann, C, Laustsen, C, Stephenson, R S & Anderson, R H 2020, ' Anatomically correct assessment of the orientation of the cardiomyocytes using diffusion tensor imaging ', NMR in Biomedicine, vol. 33, no. 3, e4205 . https://doi.org/10.1002/nbm.4205
Diffusion tensor imaging has been used for assessing the orientation of cardiac myocytes for decades. Striking methodological differences exist between studies when quantifying these orientations. This limits the comparability between studies, and im