Zobrazeno 1 - 10
of 333
pro vyhledávání: '"Robert S Dipaola"'
Autor:
David J Foran, Wenjin Chen, Huiqi Chu, Evita Sadimin, Doreen Loh, Gregory Riedlinger, Lauri A Goodell, Shridar Ganesan, Kim Hirshfield, Lorna Rodriguez, Robert S DiPaola
Publikováno v:
Cancer Informatics, Vol 16 (2017)
Leading institutions throughout the country have established Precision Medicine programs to support personalized treatment of patients. A cornerstone for these programs is the establishment of enterprise-wide Clinical Data Warehouses. Working shoulde
Externí odkaz:
https://doaj.org/article/85a2e577daa248819b7810112e4bbac6
Autor:
Raghav K Padmanabhan, Vinay H Somasundar, Sandra D Griffith, Jianliang Zhu, Drew Samoyedny, Kay See Tan, Jiahao Hu, Xuejun Liao, Lawrence Carin, Sam S Yoon, Keith T Flaherty, Robert S Dipaola, Daniel F Heitjan, Priti Lal, Michael D Feldman, Badrinath Roysam, William M F Lee
Publikováno v:
PLoS ONE, Vol 9, Iss 3, p e90495 (2014)
Currently, no available pathological or molecular measures of tumor angiogenesis predict response to antiangiogenic therapies used in clinical practice. Recognizing that tumor endothelial cells (EC) and EC activation and survival signaling are the di
Externí odkaz:
https://doaj.org/article/b8e0757015ca4903a861212a86e9581e
Autor:
Kevin Bray, Robin Mathew, Alexandria Lau, Jurre J Kamphorst, Jing Fan, Jim Chen, Hsin-Yi Chen, Anahita Ghavami, Mark Stein, Robert S DiPaola, Donna Zhang, Joshua D Rabinowitz, Eileen White
Publikováno v:
PLoS ONE, Vol 7, Iss 7, p e41831 (2012)
mTOR inhibitors are used clinically to treat renal cancer but are not curative. Here we show that autophagy is a resistance mechanism of human renal cell carcinoma (RCC) cell lines to mTOR inhibitors. RCC cell lines have high basal autophagy that is
Externí odkaz:
https://doaj.org/article/6ba4d2c1b1124f52914b4f6ce3ca12ad
Autor:
Hilary L. Surratt, Janet K. Otachi, Emily Slade, Philip A. Kern, Victoria King, Thomas H. Kelly, Robert S. DiPaola
Publikováno v:
Journal of Clinical and Translational Science, Vol 7 (2023)
Abstract Introduction: Optimizing the effectiveness of a team-based approach to unite multiple disciplines in advancing specific translational areas of research is foundational to improving clinical practice. The current study was undertaken to exam
Externí odkaz:
https://doaj.org/article/0b3594d11285482cbe8d782ceee48f0d
Autor:
Emily Slade, Philip A. Kern, Robert L. Kegebein, Chang Liu, Joel C. Thompson, Thomas H. Kelly, Victoria L. King, Robert S. DiPaola, Hilary L. Surratt
Publikováno v:
Journal of Clinical and Translational Science, Vol 7 (2023)
Abstract Introduction: Impactful, transdisciplinary scientific discoveries are created by teams of researchers spanning multiple disciplines, but collaboration across disciplines can be challenging. We examined how team dynamics and collaboration ar
Externí odkaz:
https://doaj.org/article/6a2d7c8b9af9458f9c83fe8dc3b46107
Autor:
Zin W. Myint, William H. St. Clair, Stephen E. Strup, Donglin Yan, Ning Li, Derek B. Allison, Laurie E. McLouth, Carleton S. Ellis, Peng Wang, Andrew C. James, Patrick J. Hensley, Danielle E. Otto, Susanne M. Arnold, Robert S. DiPaola, Jill M. Kolesar
Publikováno v:
Cancers; Volume 15; Issue 9; Pages: 2505
Purpose: Cannabinoids (CBD) have anti-tumor activity against prostate cancer (PCa). Preclinical studies have demonstrated a significant decrease in prostate specific antigen (PSA) protein expression and reduced tumor growth in xenografts of LNCaP and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc4ddbeb8b4a4ea8be873fa6375fab57
Autor:
Karam El-Bayoumy, Robert S. DiPaola, Susan Goodin, Matthew G. Kaag, Aaron Baker, Amy Ciccarella, Terryl J. Hartman, Arthur Berg, Eugene J. Lengerich, Jiangang Liao, Wanda Neidig, Raghu Sinha, Ana M. Calcagnotto, Arun Das, John P. Richie
Epidemiologic and laboratory studies indicate that dietary selenium protects against prostate cancer. Results from clinical trials suggest that selenium-enriched yeast (SY) but not selenomethionine (SeMet) may be effective at reducing prostate cancer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1fe14fd45d7d95f2d3aaec50088795f1
https://doi.org/10.1158/1940-6207.c.6544832
https://doi.org/10.1158/1940-6207.c.6544832
Autor:
Eileen White, Robert S. DiPaola, Vassiliki Karantza-Wadsworth, Shridar Ganesan, Michael May, Cristina M. Karp, Hsin-Yi Chen, Kevin Bray
Supplementary Data from Bcl-2 Modulation to Activate Apoptosis in Prostate Cancer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ee1b95696173bcb6703299a413291b6
https://doi.org/10.1158/1541-7786.22518924.v1
https://doi.org/10.1158/1541-7786.22518924.v1
Autor:
Eileen White, Robert S. DiPaola, Vassiliki Karantza-Wadsworth, Shridar Ganesan, Michael May, Cristina M. Karp, Hsin-Yi Chen, Kevin Bray
Apoptosis resistance is a hallmark of cancer linked to disease progression and treatment resistance, which has led to the development of anticancer therapeutics that restore apoptotic function. Antiapoptotic Bcl-2 is frequently overexpressed in refra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::708f06bbee332ef052a40e1fa7a3a7c0
https://doi.org/10.1158/1541-7786.c.6542181
https://doi.org/10.1158/1541-7786.c.6542181
Autor:
Alicia K, Morgans, Yu-Hui, Chen, David F, Jarrard, Michael, Carducci, Glenn, Liu, Mario, Eisenberger, Elizabeth R, Plimack, Alan, Bryce, Jorge A, Garcia, Robert, Dreicer, Nicholas J, Vogelzang, Joel, Picus, Daniel, Shevrin, Maha, Hussain, Robert S, DiPaola, David, Cella, Christopher J, Sweeney
Publikováno v:
The Prostate. 82:1176-1185
E3805 (CHAARTED) is a phase 3 trial demonstrating improved survival for men with metastatic hormone-sensitive prostate cancer (mHSPC) randomized to treatment with docetaxel (D) and androgen-deprivation therapy (ADT) versus ADT alone. We assessed the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6888e81ae01f259e2d26d59b01bed4b9
https://doi.org/10.1002/pros.24369
https://doi.org/10.1002/pros.24369