Zobrazeno 1 - 10
of 227
pro vyhledávání: '"Robert S, Paton"'
Autor:
Thomas Ward, Martyn Fyles, Alex Glaser, Robert S. Paton, William Ferguson, Christopher E. Overton
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-16 (2024)
Abstract The COVID-19 pandemic led to 231,841 deaths and 940,243 hospitalisations in England, by the end of March 2023. This paper calculates the real-time infection hospitalisation risk (IHR) and infection fatality risk (IFR) using the Office for Na
Externí odkaz:
https://doaj.org/article/a784305234dd411a88410410ab07595e
Autor:
Stefan Wiesler, Goh Sennari, Mihai V. Popescu, Kristen E. Gardner, Kazuhiro Aida, Robert S. Paton, Richmond Sarpong
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-8 (2024)
Abstract Skeletal modifications enable elegant and rapid access to various derivatives of a compound that would otherwise be difficult to prepare. They are therefore a powerful tool, especially in the synthesis of natural products or drug discovery,
Externí odkaz:
https://doaj.org/article/47526fae09bf4a7f99b8d039039389f0
Autor:
Thomas Ward, Christopher E. Overton, Robert S. Paton, Rachel Christie, Fergus Cumming, Martyn Fyles
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-12 (2024)
Abstract In May 2022, individuals infected with the monkeypox virus were detected in the UK without clear travel links to endemic areas. Understanding the clinical characteristics and infection severity of mpox is necessary for effective public healt
Externí odkaz:
https://doaj.org/article/3b1c7049921c4113a259617b27ceaabf
Autor:
Guilian Luchini, Robert S. Paton
Publikováno v:
ACS Physical Chemistry Au, Vol 4, Iss 3, Pp 259-267 (2024)
Externí odkaz:
https://doaj.org/article/e8e0928abad9484f9f2db7b72d99aec9
Autor:
Jonathon Mellor, Rachel Christie, Christopher E. Overton, Robert S. Paton, Rhianna Leslie, Maria Tang, Sarah Deeny, Thomas Ward
Publikováno v:
Communications Medicine, Vol 3, Iss 1, Pp 1-12 (2023)
Abstract Background Seasonal influenza places a substantial burden annually on healthcare services. Policies during the COVID-19 pandemic limited the transmission of seasonal influenza, making the timing and magnitude of a potential resurgence diffic
Externí odkaz:
https://doaj.org/article/a598b2dabf744195ab09cd260b975e9d
Autor:
Jonathon Mellor, Rachel Christie, Christopher E. Overton, Robert S. Paton, Rhianna Leslie, Maria Tang, Sarah Deeny, Thomas Ward
Publikováno v:
Communications Medicine, Vol 4, Iss 1, Pp 1-2 (2024)
Externí odkaz:
https://doaj.org/article/a108e8db00084b5babc55fd0b023200b
Autor:
Luke J. Dowman, Sameer S. Kulkarni, Juan V. Alegre-Requena, Andrew M. Giltrap, Alexander R. Norman, Ashish Sharma, Liliana C. Gallegos, Angus S. Mackay, Adarshi P. Welegedara, Emma E. Watson, Damian van Raad, Gerhard Niederacher, Susanne Huhmann, Nicholas Proschogo, Karishma Patel, Mark Larance, Christian F. W. Becker, Joel P. Mackay, Girish Lakhwani, Thomas Huber, Robert S. Paton, Richard J. Payne
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-12 (2022)
The modification of peptides and proteins for application in drug discovery and chemical biology is currently a rapidly growing field of research. Here, the authors report a photocatalytic diselenide contraction method for the dimerization and site-s
Externí odkaz:
https://doaj.org/article/ada06c11e046408eba2e63c6b196deda
Autor:
Sudip Maiti, Yingzi Li, Sheuli Sasmal, Srimanta Guin, Trisha Bhattacharya, Goutam Kumar Lahiri, Robert S. Paton, Debabrata Maiti
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-5 (2022)
Externí odkaz:
https://doaj.org/article/91da22b2c2454f56aff187aba6a048a2
Autor:
Sudip Maiti, Yingzi Li, Sheuli Sasmal, Srimanta Guin, Trisha Bhattacharya, Goutam Kumar Lahiri, Robert S. Paton, Debabrata Maiti
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-10 (2022)
Biaryls are privileged structural motif used in the discovery and design of therapeutics with high affinity and specificity for a broad range of protein targets. Herein, the authors develop a robust strategy for para-C–H arylation of arenes with a
Externí odkaz:
https://doaj.org/article/fef7d57b5c184bbd9e86f67bf2b923d7
Autor:
Roman Belle, Jos J. A. G. Kamps, Jordi Poater, Kiran Kumar, Bas J. G. E. Pieters, Eidarus Salah, Timothy D. W. Claridge, Robert S. Paton, F. Matthias Bickelhaupt, Akane Kawamura, Christopher J. Schofield, Jasmin Mecinović
Publikováno v:
Communications Chemistry, Vol 5, Iss 1, Pp 1-11 (2022)
N ε-methylation of lysine residues in histones plays an essential role in the regulation of eukaryotic transcription, and understanding the extent to which histone N ε-methyllysine readers and erasers can manifest selectivity is of fundamental and
Externí odkaz:
https://doaj.org/article/099bbfd2e1894d158c026e859ca05b14