Zobrazeno 1 - 10
of 92
pro vyhledávání: '"Robert S, Mittler"'
Autor:
Arata Itoh, Lorenzo Ortiz, Kritika Kachapati, Yuehong Wu, David Adams, Kyle Bednar, Shibabrata Mukherjee, Claire Chougnet, Robert S. Mittler, Yi-Guang Chen, Laurence Dolan, William M. Ridgway
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
We show here that soluble CD137 (sCD137), the alternately spliced gene product of Tnfsfr9, effectively treats acute type 1 diabetes (T1D) in nonobese diabetic (NOD) mice. sCD137 significantly delayed development of end-stage disease, preserved insuli
Externí odkaz:
https://doaj.org/article/a1f4bc23defc4c90872138307eddea17
Autor:
Caitlin Bohannon, Ryan Powers, Lakshmipriyadarshini Satyabhama, Ang Cui, Christopher Tipton, Miri Michaeli, Ioanna Skountzou, Robert S. Mittler, Steven H. Kleinstein, Ramit Mehr, Frances Eun-Yun Lee, Ignacio Sanz, Joshy Jacob
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-13 (2016)
Long-lived IgG plasma cells develop in germinal centres and then home to the bone marrow and persist for a lifetime. Here the authors identify long-lived IgM plasma cells in the murine spleen, which carry IgH mutations but can develop independently o
Externí odkaz:
https://doaj.org/article/cac2164087834241a0295662d5889fe7
Chemotherapy can precondition for immunotherapy by creating an environment for homeostatic lymphoproliferation and eliminating some of the suppressive immune networks. We found that combination therapy with anti-4-1BB and cyclophosphamide (CTX) produ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d12346b4a30f682a46b5e9341068d5c
https://doi.org/10.1158/1535-7163.c.6531951.v1
https://doi.org/10.1158/1535-7163.c.6531951.v1
Supplementary Fig. from Mechanisms involved in synergistic anticancer effects of anti-4-1BB and cyclophosphamide therapy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a93fd39bdff9aa54fd2333aca832ad3c
https://doi.org/10.1158/1535-7163.22485462
https://doi.org/10.1158/1535-7163.22485462
Autor:
Caitlin Bohannon, Ryan Powers, Lakshmipriyadarshini Satyabhama, Ang Cui, Christopher Tipton, Miri Michaeli, Ioanna Skountzou, Robert S. Mittler, Steven H. Kleinstein, Ramit Mehr, Frances Eun-Hyung Lee, Ignacio Sanz, Joshy Jacob
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-1 (2016)
Nature Communications 7: Article number: 11826 (2016); Published: 7 June 2016; Updated: 16 August 2016 The original version of this Article contained an error in the spelling of the author Frances Eun-Hyung Lee that was incorrectly given as Francis E
Externí odkaz:
https://doaj.org/article/659655c3437d43719b63075ee67a5eb1
Publikováno v:
Monoclonal Antibodies and T Cell Products ISBN: 9780429277115
Monoclonal Antibodies and T Cell Products
Monoclonal Antibodies and T Cell Products
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3da7fa1f75d784d36b8b54e9c1fde610
https://doi.org/10.1201/9780429277115-4
https://doi.org/10.1201/9780429277115-4
Autor:
Gregory A. Poland, Nina Marano, Han Li, Carol L. K. Sabourin, Vera A. Semenova, Scott D. Parker, Wendy A. Keitel, Janiine Babcock, Nancy A. Niemuth, April M. Brys, Thomas L. Rudge, Jennifer G. Wright, Robert M. Jacobson, Rafi Ahmed, Brian D. Plikaytis, Harry L. Keyserling, Conrad P. Quinn, Jens Wrammert, Chris C. Ibegbu, Jarad Schiffer, Robert S. Mittler, Hana M. El Sahly
Publikováno v:
Clinical and Vaccine Immunology. 23:326-338
Protective antigen (PA)-specific antibody and cell-mediated immune (CMI) responses to annual and alternate booster schedules of anthrax vaccine adsorbed (AVA; BioThrax) were characterized in humans over 43 months. Study participants received 1 of 6 v
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27a732d0ac4ac4cffaedb25fccac7d53
https://doi.org/10.1128/cvi.00696-15
https://doi.org/10.1128/cvi.00696-15
Autor:
Kyle J. Bednar, William M. Ridgway, Andrew B. Herr, Jennifer M. Hinerman, Kritika Kachapati, Yuehong Wu, David E. Adams, Robert S. Mittler, Michael B. Jordan
Publikováno v:
Journal of Autoimmunity. 47:94-103
Nonobese diabetic (NOD) mice are genetically programmed to spontaneously develop type one diabetes (T1D). Multiple Insulin dependent diabetes (Idd) genetic loci have been identified but their functional effects are mostly poorly understood. TnfsfR9,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c7521a88bfecd0c7d05f3840ce03be5
https://doi.org/10.1016/j.jaut.2013.09.002
https://doi.org/10.1016/j.jaut.2013.09.002
Autor:
Jae-A Han, Jong S. Lee, Byoung S. Kwon, Hong R. Cho, Hye Jin Kim, Kyung Min Kim, Hee J. Cha, Robert S. Mittler, Ahra Kim, Yoonkyung Do, Sumi Koo, Byungsuk Kwon
Publikováno v:
The Journal of Immunology. 191:2657-2664
Damage-associated molecular patterns released from damaged kidney cells initiate postischemic inflammation, an essential step in the progression of kidney ischemia–reperfusion injury (IRI). However, the mechanism that coordinates this highly specif
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7349f33a5acf30926500cdac4cf64543
https://doi.org/10.4049/jimmunol.1300358
https://doi.org/10.4049/jimmunol.1300358
Autor:
Miri Michaeli, Joshy Jacob, Lakshmipriyadarshini Satyabhama, Ignacio Sanz, Caitlin Bohannon, Ang Cui, Ramit Mehr, Ioanna Skountzou, Steven H. Kleinstein, Robert S. Mittler, Frances Eun-Hyung Lee, Christopher M. Tipton, Ryan Powers
Publikováno v:
Nature Communications
Nature Communications, Vol 7, Iss 1, Pp 1-13 (2016)
Nature Communications, Vol 7, Iss 1, Pp 1-13 (2016)
Long-lived plasma cells are critical to humoral immunity as a lifelong source of protective antibodies. Antigen-activated B cells—with T-cell help—undergo affinity maturation within germinal centres and persist as long-lived IgG plasma cells in t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e18e1582233725f8efb5879e0fef0219
https://pubmed.ncbi.nlm.nih.gov/27527920
https://pubmed.ncbi.nlm.nih.gov/27527920