Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Robert Rissman"'
Autor:
Michiyo Iba, Changyoun Kim, Jazmin Florio, Michael Mante, Anthony Adame, Edward Rockenstein, Somin Kwon, Robert Rissman, Eliezer Masliah
Publikováno v:
Frontiers in Neuroscience, Vol 14 (2020)
Progressive accumulation of the pre-synaptic protein α-synuclein (α-syn) has been strongly associated with the pathogenesis of neurodegenerative disorders of the aging population such as Alzheimer’s disease (AD), Parkinson’s disease (PD), demen
Externí odkaz:
https://doaj.org/article/5d7cc973243a43d7b92a119b6bac5e9a
Autor:
Jacqueline Kulbe, Alexandra Anh Le, Michael Mante, Jazmin Florio, Anna Eizabeth Laird, Mary Swinton, Robert Rissman, Jerel Fields
Central nervous system (CNS) dysfunction remains prevalent in people with HIV (PWH) despite effective antiretroviral therapy (ART). There is evidence that low-level HIV infection and ART drugs may contribute to CNS damage in the brain of PWH with sup
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3efbb99691ceb7b14a404b37794204a5
https://doi.org/10.21203/rs.3.rs-2652625/v1
https://doi.org/10.21203/rs.3.rs-2652625/v1
Autor:
Jacqueline Kulbe, Mary Swinton, Anh Le, Anna Laird, Nicholas Scrivens, Michael Mante, Jazmin Florio, Robert Rissman, Jerel Adam Fields
Publikováno v:
Biological Psychiatry. 93:S186-S187
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::386236ad11ec70513cb76999484d9958
https://doi.org/10.1016/j.biopsych.2023.02.471
https://doi.org/10.1016/j.biopsych.2023.02.471
Autor:
Michiyo Iba, Changyoun Kim, Michelle Sallin, Somin Kwon, Anjali Verma, Cassia Overk, Robert Rissman, Ranjan Sen, Jyoti Sen, Eliezer Masliah
Background: ɑ-synuclein (ɑ-syn) is a presynaptic protein which progressively accumulates in neuronal and non-neuronal cells in neurodegenerative diseases such as Parkinson’s disease (PD), dementia with Lewy bodies (DLB), and multiple system atrop
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0bff778797990ca786fc1c745e2c6cab
https://doi.org/10.21203/rs.3.rs-21922/v1
https://doi.org/10.21203/rs.3.rs-21922/v1
Autor:
Wouter tenVoorde, Chika Akinseye, Ismahaan Abdisalaam, Selinde Wind, Naomi Klarenbeek, Menthe Bergmans, Martijn vanDoorn, Robert Rissmann, Rejbinder Kaur, Sarah Hotee, Katie Foster, Arati Nair, Lea Fortunato, Colin Macphee, Sarah Mole, Katrine Baumann, Richard Brigandi
Publikováno v:
Clinical and Translational Science, Vol 16, Iss 10, Pp 1856-1865 (2023)
Abstract Pharmacological challenge models are deployed to evaluate drug effects during clinical development. Intradermal injection of Substance P (SP) neuropeptide, a potential challenge agent for investigating local mediators, is associated with whe
Externí odkaz:
https://doaj.org/article/08287e6b2cc64b848f3fdbb071032292
Autor:
Stefan J. Jodl, Wouter tenVoorde, Stefan Klein, Andrea Wagenfeld, Frank S. Zollmann, Maximilian Feldmüller, Naomi B. Klarenbeek, Digna T. deBruin, Manon A. A. Jansen, Robert Rissmann, Beate Rohde, Matthijs Moerland
Publikováno v:
Clinical and Translational Science, Vol 17, Iss 3, Pp n/a-n/a (2024)
Abstract This study evaluated and characterized the pharmacological activity of the orally administered interleukin‐1 receptor‐associated kinase 4 (IRAK4) inhibitors BAY1834845 (zabedosertib) and BAY1830839 in healthy male volunteers. Participant
Externí odkaz:
https://doaj.org/article/89d49a01219946438e0011ce97dc1147
Autor:
Diane M. Thiboutot, Noah Craft, Robert Rissmann, Ewa Gatlik, Malika Souquières, Julie Jones, Christian Loesche
Publikováno v:
Journal of Dermatological Treatment, Vol 34, Iss 1 (2023)
Background CJM112 is a potent anti-IL-17A monoclonal antibody, whose clinical efficacy in psoriasis was recently documented. This study aimed to assess the effect of IL-17A blockade, using CJM112, in patients with moderate to severe acne. Methods A r
Externí odkaz:
https://doaj.org/article/be401d9604254640b0c64a21d10b9147
Autor:
Lisa Pagan, Bertine W. Huisman, Michelle van der Wurff, Rosanne G. C. Naafs, Frank H. J. Schuren, Ingrid M. J. G. Sanders, Wiep Klaas Smits, Romy D. Zwittink, Jacobus Burggraaf, Robert Rissmann, Jurgen M. J. Piek, Jannie G. E. Henderickx, Mariëtte I. E. van Poelgeest
Publikováno v:
Frontiers in Microbiology, Vol 14 (2023)
BackgroundThe role of the vulvar microbiome in the development of (pre)malignant vulvar disease is scarcely investigated. The aim of this exploratory study was to analyze vulvar microbiome composition in lichen sclerosus (LS) and vulvar high-grade sq
Externí odkaz:
https://doaj.org/article/2b7bddac6cb54f87b3c2c8152822db06
Autor:
Andreea Nădăban, Jannik Rousel, Dounia El Yachioui, Gerrit S. Gooris, Charlotte M. Beddoes, Robert M. Dalgliesh, Marc Malfois, Robert Rissmann, Joke A. Bouwstra
Publikováno v:
Journal of Lipid Research, Vol 64, Iss 8, Pp 100400- (2023)
The lipids in the uppermost layer of the skin, the stratum corneum (SC), play an important role in the skin barrier function. The three main subclasses in the SC lipid matrix are ceramides (CER), cholesterol, and free fatty acids. In inflammatory ski
Externí odkaz:
https://doaj.org/article/76325d43d081451c8bc876cc2b41ec5b
Autor:
Salma Assil, Thomas P. Buters, Pieter W. Hameeteman, Charlie Hallard, Nicoline Treijtel, Tessa Niemeyer – Van der Kolk, Marieke L. de Kam, Edwin F. I. I. I. Florencia, Errol P. Prens, Martijn B. A. van Doorn, Robert Rissmann, Naomi B. Klarenbeek, Manon A. A. Jansen, Matthijs Moerland
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Imiquimod (IMQ) is a topical agent that induces local inflammation via the Toll-like receptor 7 pathway. Recently, an IMQ-driven skin inflammation model was developed in healthy volunteers for proof-of-pharmacology trials. The aim of this study was t
Externí odkaz:
https://doaj.org/article/f03a8555dda44e0c8f9b4a37d47243ce