Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Robert Reddick"'
Autor:
Darpan I Patel, Kira Abuchowski, Roble Bedolla, Paul Rivas, Nicolas Musi, Robert Reddick, A Pratap Kumar
Publikováno v:
PLoS ONE, Vol 14, Iss 12, p e0226187 (2019)
The purpose of this investigation was to compare the antitumorigenic effects of the natural product Nexrutine to voluntary wheel running (VWR) in the transgenic adenocarcinoma of the mouse prostate (TRAMP) model. Forty-five, 10-week old TRAMP mice we
Externí odkaz:
https://doaj.org/article/d87e753d41974e38b4498fa6b0969a4c
Autor:
Addanki P. Kumar, Susan M. Fischer, Huamin Wang, Amanda Peterson, Scott Kopetz, Robert Reddick, James W. Freeman, Divya Chakravarthy, Paul Rivas, Roble Bedolla, Jianping Xie, Jingjing Gong
PDF file - 1727KB, Nx treatment reduces protein levels of p65, p50 and pStta3 in Ras transformed cells and lower exposure blot of data presented in Fig 2.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15945d8035ed074562ae847c16d7a2f0
https://doi.org/10.1158/1078-0432.22451874.v1
https://doi.org/10.1158/1078-0432.22451874.v1
Autor:
Addanki P. Kumar, Susan M. Fischer, Huamin Wang, Amanda Peterson, Scott Kopetz, Robert Reddick, James W. Freeman, Divya Chakravarthy, Paul Rivas, Roble Bedolla, Jianping Xie, Jingjing Gong
PDF file - 1241KB, Nx treatment inhibits Cox-2 levels and activity.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06ac27ca45d10d032605f223e8527366
https://doi.org/10.1158/1078-0432.22451868
https://doi.org/10.1158/1078-0432.22451868
Autor:
Addanki P. Kumar, Susan M. Fischer, Huamin Wang, Amanda Peterson, Scott Kopetz, Robert Reddick, James W. Freeman, Divya Chakravarthy, Paul Rivas, Roble Bedolla, Jianping Xie, Jingjing Gong
PDF file - 1144KB, Histograms of FITC-Annexin staining.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e1ffc015fdc8e9eb628aa685595ed40
https://doi.org/10.1158/1078-0432.22451877
https://doi.org/10.1158/1078-0432.22451877
Autor:
Addanki P. Kumar, Susan M. Fischer, Huamin Wang, Amanda Peterson, Scott Kopetz, Robert Reddick, James W. Freeman, Divya Chakravarthy, Paul Rivas, Roble Bedolla, Jianping Xie, Jingjing Gong
PDF file - 1660KB, Effects of Stat3 knockdown on Nx-induced proliferation inhibition.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::58c02981e9bd2ae28f40cbd32a19b07b
https://doi.org/10.1158/1078-0432.22451871.v1
https://doi.org/10.1158/1078-0432.22451871.v1
Autor:
Addanki P. Kumar, Susan M. Fischer, Huamin Wang, Amanda Peterson, Scott Kopetz, Robert Reddick, James W. Freeman, Divya Chakravarthy, Paul Rivas, Roble Bedolla, Jianping Xie, Jingjing Gong
Purpose: Near equal rates of incidence and mortality emphasize the need for novel targeted approaches for better management of patients with pancreatic cancer. Inflammatory molecules NF-κB and STAT3 are overexpressed in pancreatic tumors. Inhibition
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::630449e5b65e4b990d96e24d878812ef
https://doi.org/10.1158/1078-0432.c.6522312.v1
https://doi.org/10.1158/1078-0432.c.6522312.v1
Publikováno v:
Cell Immunol
For over 70 years experimental autoimmune encephalomyelitis (EAE) has been induced with myelin autoantigens emulsified in complete Freund’s adjuvant (CFA) which has significant side effects such as pain, inflammation, and tissue necrosis at the inj
Autor:
Addanki P. Kumar, Shih-Bo Huang, Sridharan Jayamohan, Jianping Xie, Roble Bedolla, Izhar Singh Batth, Robert Reddick, Pawel A. Osmulski, Hiroshi Miyamoto, Rita Ghosh, I-Tien Yeh, Michelle R. Villarreal, Jingjing Gong, Brian Keppler, Divya Chakravarthy, Michael A. Liss, Paul Rivas
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 1852, p 1852 (2021)
International Journal of Molecular Sciences
Volume 22
Issue 4
International Journal of Molecular Sciences
Volume 22
Issue 4
2-Methoxyestradiol (2-ME2) possesses anti-tumorigenic activities in multiple tumor models with acceptable tolerability profile in humans. Incomplete understanding of the mechanism has hindered its development as an anti-tumorigenic compound. We have
Autor:
Roble Bedolla, Li-Ju Wang, Zhao Lai, Yu-Chiao Chiu, Pawel A. Osmulski, Yi Chen, Xiaoyu Yang, Addanki P. Kumar, Shih-Bo Huang, Maria Gaczynska, Dinesh Thapa, Paul Rivas, Rita Ghosh, Robert Reddick, C. Shudde, Suleman S. Hussain, Hiroshi Miyamoto, Amanda R. Muñoz
Publikováno v:
Cancer letters. 505
The NAD+-dependent deacetylase, Sirtuin 1 (SIRT1) is involved in prostate cancer pathogenesis. However, the actual contribution is unclear as some reports propose a protective role while others suggest it is harmful. We provide evidence for a context
Autor:
Roble Bedolla, Shih-Bo Huang, Hiroshi Miyamoto, Tim H M Huang, Brad H. Pollock, I-Tien Yeh, Paul Rivas, Suleman S. Hussain, Addanki P. Kumar, Gregory P. Swanson, Nikos Papanikolaou, Ganesh Narayanasamy, Rita Ghosh, Robert Reddick, Joseph W. Basler
Publikováno v:
Cancer Letters. 433:232-241
Radiation therapy (XRT) is a standard treatment for prostate cancer (PCa). Although dose escalation increases local control, toxicity hampers further escalation. Broader improvement will be possible by the addition of adjuvant therapies, which can sy