Zobrazeno 1 - 10
of 69
pro vyhledávání: '"Robert Ranaldi"'
Autor:
Ewa Galaj, Eddy D Barrera, Olivia L Lynch, Rachel Diodati, Ashley Thomas, Piper Schneider, Hayley Lenhard, Apoorva Vashisht, Robert Ranaldi
Publikováno v:
The international journal of neuropsychopharmacology.
Background Reward-related learning, where animals form associations between rewards and stimuli (i.e., conditioned stimuli [CS]) that predict or accompany those rewards, is an essential adaptive function for survival. Methods In this study, we invest
Autor:
Ewa Galaj, Robert Ranaldi
Publikováno v:
Neurosci Biobehav Rev
A major goal in psychology is to understand how environmental stimuli associated with primary rewards come to function as conditioned stimuli, acquiring the capacity to elicit similar responses to those elicited by primary rewards. Our neurobiologica
Autor:
Robert Ranaldi, Patrick Timken, Daleya Parasram, Tasmia Ali, Sixue Zhang, Omar Moukha-Chafiq, Corinne Augelli-Szafran, John M. Streicher
Publikováno v:
Neuroscience Letters. 806:137237
Publikováno v:
Addict Biol
Chemical compounds that target dopamine (DA) D1 or D3 receptors have shown promise as potential interventions in animal models of cue-induced relapse. However, undesirable side effects or pharmacodynamic profiles have limited the advancement of new c
Autor:
Scott Ewing, Stephen Greenberger, Eddy D. Barrera, Priscila Hachimine, Lacey Loughlin, Robert Ranaldi
Publikováno v:
Drug Alcohol Depend
Background Contemporary treatments for heroin use disorder demonstrate only limited efficacy when the goals are long term abstinence and prevention of relapse. We have demonstrated that environmental enrichment (EE) reduces cue-induced heroin reinsta
Publikováno v:
Neurosci Lett
The purpose of this study was to investigate the effects of (−)-stepholidine (SPD), a compound with dopamine D1 partial agonist and D2/D3 antagonist properties, on the development and expression of cocaine conditioned place preference (CPP). Subjec
Publikováno v:
Neurobiol Learn Mem
This study investigated the role of calcium2+/calmodulin-dependent protein kinase II (CaMKII), a protein in the second messenger pathway of NMDA receptors, in the ventral tegmental area (VTA) in the acquisition and performance of conditioned approach
Publikováno v:
Alcohol Clin Exp Res
BACKGROUND AND PURPOSE: Binge drinking is a serious problem among adolescents and young adults despite its adverse consequences on the brain and behavior. One area that remains poorly understood concerns the impact of chronic intermittent ethanol (CI
Autor:
Robert Ranaldi, Ewa Galaj
Publikováno v:
Behavioural Brain Research. 348:65-73
We tested whether (1) the capacity of a reward-associated conditioned stimulus (CS) to cause conditioned activation of ventral tegmental area (VTA) dopamine (DA) neurons is associated with its capacity to elicit conditioned approach responses and (2)
Publikováno v:
Neuroscience & Biobehavioral Reviews. 89:13-28
In the search for efficacious pharmacotherapies to treat cocaine addiction much attention has been given to agents targeting dopamine D1 or D3 receptors because of the involvement of these receptors in drug-related behaviors. D1-like and D3 receptor